{"id":"https://openalex.org/W2806230093","doi":"https://doi.org/10.1109/isbi.2018.8363774","title":"Unsupervised analysis of mouse social behaviour reveals how hyperactivity impacts social aspects in a mouse model of autism","display_name":"Unsupervised analysis of mouse social behaviour reveals how hyperactivity impacts social aspects in a mouse model of autism","publication_year":2018,"publication_date":"2018-04-01","ids":{"openalex":"https://openalex.org/W2806230093","doi":"https://doi.org/10.1109/isbi.2018.8363774","mag":"2806230093"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2018.8363774","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2018.8363774","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007603953","display_name":"Oscar Bauer","orcid":null},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"funder","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Oscar Bauer","raw_affiliation_strings":["Institut Pasteur, Unit\u00e9 d\u2019 Analyse d'Images Biologiques, France","Institut Pasteur, Unit\u00e9 d' Analyse d'Images Biologiques, France"],"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Unit\u00e9 d\u2019 Analyse d'Images Biologiques, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Institut Pasteur, Unit\u00e9 d' Analyse d'Images Biologiques, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084411567","display_name":"Thomas Bourgeron","orcid":"https://orcid.org/0000-0001-8164-9220"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"funder","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Thomas Bourgeron","raw_affiliation_strings":["Institut Pasteur, Unit\u00e9 de G\u00e9n\u00e9tique Humaine et Fonctions Cognitives, France"],"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Unit\u00e9 de G\u00e9n\u00e9tique Humaine et Fonctions Cognitives, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003562216","display_name":"Jean\u2010Christophe Olivo\u2010Mar\u00edn","orcid":"https://orcid.org/0000-0001-6796-0696"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"funder","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Christophe Olivo-Marin","raw_affiliation_strings":["Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR"],"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Paris, \u00c3\u017dle-de-France, FR","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042991649","display_name":"Elodie Ey","orcid":"https://orcid.org/0000-0002-8202-3163"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"funder","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Elodie Ey","raw_affiliation_strings":["Institut Pasteur, Unit\u00e9 de G\u00e9n\u00e9tique Humaine et Fonctions Cognitives, France"],"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Unit\u00e9 de G\u00e9n\u00e9tique Humaine et Fonctions Cognitives, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089374942","display_name":"Fabrice de Chaumont","orcid":"https://orcid.org/0000-0001-7613-7204"},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"funder","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fabrice de Chaumont","raw_affiliation_strings":["Institut Pasteur, Unit\u00e9 d\u2019 Analyse d'Images Biologiques, France","Institut Pasteur, Unit\u00e9 d' Analyse d'Images Biologiques, France"],"affiliations":[{"raw_affiliation_string":"Institut Pasteur, Unit\u00e9 d\u2019 Analyse d'Images Biologiques, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Institut Pasteur, Unit\u00e9 d' Analyse d'Images Biologiques, France","institution_ids":["https://openalex.org/I157536573"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5007603953"],"corresponding_institution_ids":["https://openalex.org/I157536573"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05620073,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1149","last_page":"1152"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10699","display_name":"Primate Behavior and Ecology","score":0.9865000247955322,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.9825999736785889,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autism","display_name":"Autism","score":0.8697284460067749},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.6903990507125854},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.43945789337158203},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.37332212924957275},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3677014708518982},{"id":"https://openalex.org/keywords/cognitive-psychology","display_name":"Cognitive psychology","score":0.35733601450920105},{"id":"https://openalex.org/keywords/developmental-psychology","display_name":"Developmental psychology","score":0.332793653011322},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2693241238594055}],"concepts":[{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.8697284460067749},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6903990507125854},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.43945789337158203},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.37332212924957275},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3677014708518982},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.35733601450920105},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.332793653011322},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2693241238594055},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2018.8363774","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2018.8363774","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5899999737739563,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1977591411","https://openalex.org/W2031468801","https://openalex.org/W2066555189","https://openalex.org/W2121649028","https://openalex.org/W2214000971","https://openalex.org/W2412121675","https://openalex.org/W2696803193","https://openalex.org/W2739958663"],"related_works":["https://openalex.org/W4280602684","https://openalex.org/W4310092953","https://openalex.org/W2227393071","https://openalex.org/W2082102603","https://openalex.org/W2166141227","https://openalex.org/W3133980636","https://openalex.org/W4378085486","https://openalex.org/W1995350144","https://openalex.org/W4366602711","https://openalex.org/W620566831"],"abstract_inverted_index":{"Unsupervised":[0],"classification":[1],"of":[2,22,34,40,43,69],"animal":[3],"behaviour":[4,39],"triggers":[5],"growing":[6],"interest.":[7],"Tracking":[8],"algorithms":[9],"are":[10],"allowing":[11],"more":[12,14],"and":[13,17,75],"efficient":[15],"recording":[16],"thus":[18],"produce":[19],"increasing":[20],"amount":[21],"data":[23],"to":[24,36,80,88,90],"be":[25],"classified.":[26],"In":[27],"this":[28],"context,":[29],"we":[30],"propose":[31],"two":[32],"levels":[33],"analysis":[35],"describe":[37],"the":[38,67,77],"mouse":[41],"models":[42],"neuropsychiatric":[44],"disorders.":[45,58],"We":[46,59],"studied":[47],"mice":[48],"mutated":[49],"in":[50,98],"Shank2,":[51],"a":[52],"gene":[53],"associated":[54],"with":[55,62],"autism":[56],"spectrum":[57],"compared":[60],"them":[61],"their":[63],"wildtype":[64],"littermates,":[65],"regarding":[66],"proportions":[68],"behavioural":[70],"events":[71],"classified":[72],"along":[73],"time,":[74],"also":[76],"thresholds":[78],"used":[79],"define":[81],"these":[82],"events.":[83],"The":[84],"developed":[85],"algorithm":[86],"allowed":[87],"understand":[89],"what":[91],"extent":[92],"hyperactivity":[93],"could":[94],"explain":[95],"social":[96],"deficits":[97],"Shank2":[99],"mutant":[100],"mice.":[101]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}