{"id":"https://openalex.org/W2435926399","doi":"https://doi.org/10.1109/isbi.2016.7493509","title":"Classification of multiple sclerosis lesion evolution patterns a study based on unsupervised clustering of asynchronous time-series","display_name":"Classification of multiple sclerosis lesion evolution patterns a study based on unsupervised clustering of asynchronous time-series","publication_year":2016,"publication_date":"2016-04-01","ids":{"openalex":"https://openalex.org/W2435926399","doi":"https://doi.org/10.1109/isbi.2016.7493509","mag":"2435926399"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2016.7493509","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2016.7493509","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057288130","display_name":"Simon Mure","orcid":null},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Simon Mure","raw_affiliation_strings":["Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, France","Images et Mod\u00e8les (France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"Images et Mod\u00e8les (France)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028473809","display_name":"Thomas Grenier","orcid":"https://orcid.org/0000-0002-3630-5856"},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Thomas Grenier","raw_affiliation_strings":["Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, France","Images et Mod\u00e8les (France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"Images et Mod\u00e8les (France)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080553234","display_name":"Charles R.G. Guttmann","orcid":"https://orcid.org/0000-0002-7006-9762"},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210166946","display_name":"Imaging Center","ror":"https://ror.org/05hsqsk33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210166946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles R. G. Guttmann","raw_affiliation_strings":["Harvard Medical School, Boston, MA, US","Center for Neurological Imaging (Center for Neurological Imaging, Departments of Radiology and Neurology, Brigham & Women\u2019s Hospital, Harvard Medical School, Boston, MA, U.S.A - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA, US","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Center for Neurological Imaging (Center for Neurological Imaging, Departments of Radiology and Neurology, Brigham & Women\u2019s Hospital, Harvard Medical School, Boston, MA, U.S.A - France)","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210166946","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007107044","display_name":"Fran\u00e7ois Cotton","orcid":"https://orcid.org/0000-0003-0046-2478"},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210137504","display_name":"Chimie et Biologie des Membranes et des Nanoobjects","ror":"https://ror.org/03jtzcc30","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I15057530","https://openalex.org/I4210091158","https://openalex.org/I4210128300","https://openalex.org/I4210137504","https://openalex.org/I4210160189"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Francois Cotton","raw_affiliation_strings":["Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, France","RMN et optique : De la mesure au biomarqueur (France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"RMN et optique : De la mesure au biomarqueur (France)","institution_ids":["https://openalex.org/I4210137504"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5104272651","display_name":"Hugues Benoit-Cattin","orcid":null},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Universit\u00e9 Claude Bernard Lyon 1","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Hugues Benoit-Cattin","raw_affiliation_strings":["Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, France","Images et Mod\u00e8les (France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, France","institution_ids":["https://openalex.org/I100532134"]},{"raw_affiliation_string":"Images et Mod\u00e8les (France)","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.06535209,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"3","issue":null,"first_page":"1315","last_page":"1319"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.9240000247955322,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dynamic-time-warping","display_name":"Dynamic time warping","score":0.8229552507400513},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6895886063575745},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6655012369155884},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.6281505823135376},{"id":"https://openalex.org/keywords/asynchronous-communication","display_name":"Asynchronous communication","score":0.6169788837432861},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5715552568435669},{"id":"https://openalex.org/keywords/series","display_name":"Series (stratigraphy)","score":0.4940040707588196},{"id":"https://openalex.org/keywords/lesion","display_name":"Lesion","score":0.445911705493927},{"id":"https://openalex.org/keywords/time-series","display_name":"Time series","score":0.4456864595413208},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.34170007705688477},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.21693822741508484},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.11287921667098999}],"concepts":[{"id":"https://openalex.org/C88516994","wikidata":"https://www.wikidata.org/wiki/Q1268863","display_name":"Dynamic time warping","level":2,"score":0.8229552507400513},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6895886063575745},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6655012369155884},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.6281505823135376},{"id":"https://openalex.org/C151319957","wikidata":"https://www.wikidata.org/wiki/Q752739","display_name":"Asynchronous communication","level":2,"score":0.6169788837432861},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5715552568435669},{"id":"https://openalex.org/C143724316","wikidata":"https://www.wikidata.org/wiki/Q312468","display_name":"Series (stratigraphy)","level":2,"score":0.4940040707588196},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.445911705493927},{"id":"https://openalex.org/C151406439","wikidata":"https://www.wikidata.org/wiki/Q186588","display_name":"Time series","level":2,"score":0.4456864595413208},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.34170007705688477},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.21693822741508484},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11287921667098999},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/isbi.2016.7493509","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2016.7493509","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmh:oai:HAL:hal-01432982v1","is_oa":false,"landing_page_url":"https://hal.science/hal-01432982","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE 13th International Symposium on Biomedical Imaging (ISBI 2016), Apr 2016, Prague, Czech Republic. ⟨10.1109/ISBI.2016.7493509⟩","raw_type":"Conference papers"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W54230203","https://openalex.org/W947982744","https://openalex.org/W1270085290","https://openalex.org/W2052644075","https://openalex.org/W2066319437","https://openalex.org/W2071881327","https://openalex.org/W2073916552","https://openalex.org/W2080901431","https://openalex.org/W2084534504","https://openalex.org/W2098344611","https://openalex.org/W2100782146","https://openalex.org/W2107092366","https://openalex.org/W2128160875","https://openalex.org/W2148726987","https://openalex.org/W4211254511","https://openalex.org/W4235770099","https://openalex.org/W6602235367","https://openalex.org/W6675218147"],"related_works":["https://openalex.org/W2341338763","https://openalex.org/W2950183183","https://openalex.org/W2030799363","https://openalex.org/W2032415964","https://openalex.org/W2288425735","https://openalex.org/W2349923317","https://openalex.org/W2609942398","https://openalex.org/W2764033112","https://openalex.org/W4380451100","https://openalex.org/W2772616816"],"abstract_inverted_index":{"Based":[0],"on":[1,36],"weekly":[2],"up":[3],"to":[4,24,44],"monthly":[5],"follow-up":[6],"of":[7,62],"MS":[8],"patients":[9],"over":[10],"one":[11],"year":[12],"with":[13],"T2-weighted":[14],"magnetic":[15],"resonance":[16],"images,":[17],"a":[18,56],"new":[19],"clustering":[20],"scheme":[21],"is":[22],"proposed":[23,33],"automatically":[25],"identify":[26],"lesions":[27],"sharing":[28],"similar":[29],"temporal":[30],"behaviors.":[31],"The":[32],"method,":[34],"based":[35],"spatiotemporal":[37],"mean-shift":[38],"and":[39,47],"dynamic":[40],"time":[41],"warping,":[42],"allows":[43],"detect":[45],"intra":[46],"inter-patient":[48],"similarities":[49],"in":[50],"lesion":[51,63],"evolution":[52,64],"patterns,":[53],"which":[54],"provides":[55],"quantitative":[57],"approach":[58],"towards":[59],"the":[60],"understanding":[61],"heterogeneity.":[65]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}