{"id":"https://openalex.org/W2426225900","doi":"https://doi.org/10.1109/isbi.2016.7493476","title":"3D diffusion MRI-based CAD system for early diagnosis of acute renal rejection","display_name":"3D diffusion MRI-based CAD system for early diagnosis of acute renal rejection","publication_year":2016,"publication_date":"2016-04-01","ids":{"openalex":"https://openalex.org/W2426225900","doi":"https://doi.org/10.1109/isbi.2016.7493476","mag":"2426225900"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2016.7493476","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2016.7493476","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004006894","display_name":"Mohamed Shehata","orcid":"https://orcid.org/0000-0001-6640-6183"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohamed Shehata","raw_affiliation_strings":["Bioengineering Department, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003428654","display_name":"Fahmi Khalifa","orcid":"https://orcid.org/0000-0003-3318-2851"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fahmi Khalifa","raw_affiliation_strings":["Bioengineering Department, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013054530","display_name":"Ahmed Soliman","orcid":"https://orcid.org/0000-0002-1931-3416"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ahmed Soliman","raw_affiliation_strings":["Bioengineering Department, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032476008","display_name":"Ali E. Takieldeen","orcid":"https://orcid.org/0000-0002-6223-705X"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ali Takieldeen","raw_affiliation_strings":["Bioengineering Department, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083099298","display_name":"Mohamed Abou El\u2010Ghar","orcid":"https://orcid.org/0000-0003-2713-4394"},"institutions":[{"id":"https://openalex.org/I159247623","display_name":"Mansoura University","ror":"https://ror.org/01k8vtd75","country_code":"EG","type":"education","lineage":["https://openalex.org/I159247623"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mohamed Abou El-Ghar","raw_affiliation_strings":["Radiology Department, Mansoura University, Mansoura, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology Department, Mansoura University, Mansoura, Egypt","institution_ids":["https://openalex.org/I159247623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068000455","display_name":"Ahmed Shaffie","orcid":"https://orcid.org/0000-0002-6557-6292"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ahmed Shaffie","raw_affiliation_strings":["Bioengineering Department, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019566817","display_name":"Amy C. Dwyer","orcid":null},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy C. Dwyer","raw_affiliation_strings":["Kidney Transplantation Kidney Disease Center, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kidney Transplantation Kidney Disease Center, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066085683","display_name":"Rosemary Ouseph","orcid":null},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rosemary Ouseph","raw_affiliation_strings":["Kidney Transplantation Kidney Disease Center, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kidney Transplantation Kidney Disease Center, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075057705","display_name":"Ayman El\u2010Baz","orcid":"https://orcid.org/0000-0001-7264-1323"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ayman El-Baz","raw_affiliation_strings":["Bioengineering Department, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043602973","display_name":"Robert Keynton","orcid":"https://orcid.org/0000-0001-5581-0500"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Keynton","raw_affiliation_strings":["Bioengineering-Department, University of Louisville, Louisville, KY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering-Department, University of Louisville, Louisville, KY, USA","institution_ids":["https://openalex.org/I142740786"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":10,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.2039,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.91076388,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"1177","last_page":"1180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cad","display_name":"CAD","score":0.8390119075775146},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5599848031997681},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.524541437625885},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5044809579849243},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.43061378598213196},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3846263587474823}],"concepts":[{"id":"https://openalex.org/C194789388","wikidata":"https://www.wikidata.org/wiki/Q17855283","display_name":"CAD","level":2,"score":0.8390119075775146},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5599848031997681},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.524541437625885},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5044809579849243},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.43061378598213196},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3846263587474823},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C199639397","wikidata":"https://www.wikidata.org/wiki/Q1788588","display_name":"Engineering drawing","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2016.7493476","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2016.7493476","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5199999809265137,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1554698203","https://openalex.org/W1875387157","https://openalex.org/W1973871881","https://openalex.org/W1976863536","https://openalex.org/W1985492558","https://openalex.org/W1993947467","https://openalex.org/W2046578038","https://openalex.org/W2048037029","https://openalex.org/W2055669260","https://openalex.org/W2115384210","https://openalex.org/W2117340355","https://openalex.org/W2131188038","https://openalex.org/W2133990480","https://openalex.org/W2159558450","https://openalex.org/W2295354706","https://openalex.org/W2525081227","https://openalex.org/W2614384051","https://openalex.org/W6639267569","https://openalex.org/W6683891766","https://openalex.org/W6737812783"],"related_works":["https://openalex.org/W2334610590","https://openalex.org/W2320366403","https://openalex.org/W3204197061","https://openalex.org/W4251350712","https://openalex.org/W637098845","https://openalex.org/W2410116073","https://openalex.org/W3044972437","https://openalex.org/W2033914206","https://openalex.org/W2042327336","https://openalex.org/W1522196789"],"abstract_inverted_index":{"This":[0,53],"paper":[1],"introduces":[2],"a":[3,73,108,159,196],"novel":[4],"computer":[5],"aided":[6],"diagnostic":[7,186,199],"(CAD)":[8],"system":[9,30,128,194],"for":[10],"early":[11],"diagnosis":[12],"of":[13,59,91,97,115,124,140,167,173,180,190],"acute":[14],"renal":[15,151],"rejection":[16,148,175],"(ARR)":[17],"from":[18,48],"3D":[19],"diffusion-weighted":[20],"MRI":[21],"(DW-MRI)":[22],"data":[23,36,144],"(2D":[24],"+":[25],"fe-value).":[26],"The":[27,94,121],"proposed":[28,126,192],"CAD":[29,127,193],"starts":[31],"with":[32],"aligning":[33],"the":[34,43,57,60,88,92,98,116,125,132,141,168,191],"DW-MRI":[35,143],"using":[37,63,158],"B-splines":[38],"based":[39],"registration":[40],"to":[41,130,145],"handle":[42],"motion":[44],"effects,":[45],"which":[46,69],"come":[47],"breathing":[49],"and":[50,87,118,149,162,177],"heart":[51],"beats.":[52],"is":[54,70,100,129],"followed":[55],"by":[56,72,102],"segmentation":[58],"kidney":[61,84,117],"tissue":[62],"geometric":[64],"(level-sets":[65],"based)":[66],"de-formable":[67],"model,":[68],"guided":[71],"new":[74],"stochastic":[75],"speed":[76],"relationship":[77],"that":[78],"takes":[79],"into":[80,107],"account":[81],"an":[82],"adaptive":[83],"shape":[85],"prior":[86],"visual":[89],"appearance":[90],"kidney.":[93],"pixel-wise":[95],"guidance":[96],"level-sets":[99],"obtained":[101],"integrating":[103],"these":[104],"image":[105],"features":[106],"joint":[109],"Markov-Gibbs":[110],"random":[111],"field":[112],"(MGRF)":[113],"model":[114],"its":[119],"background.":[120],"final":[122],"step":[123],"calculate":[131],"apparent":[133],"diffusion":[134],"coefficients":[135],"(ADCs)":[136],"between":[137,147],"different":[138],"b-values":[139],"segmented":[142],"distinguish":[146],"nonrejection":[150,182],"transplants.":[152],"Experimental":[153],"results":[154,187],"on":[155],"36":[156],"subjects,":[157],"KStar":[160],"classifier":[161],"leave-one-subject-out,":[163],"have":[164],"classified":[165],"87%":[166],"subjects":[169],"correctly":[170],"(26":[171],"out":[172,179],"30":[174],"kidneys":[176],"5":[178],"6":[181],"kidneys).":[183],"These":[184],"initial":[185],"hold":[188],"promise":[189],"as":[195],"reliable":[197],"non-invasive":[198],"tool.":[200]},"counts_by_year":[{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}