{"id":"https://openalex.org/W2426274714","doi":"https://doi.org/10.1109/isbi.2016.7493240","title":"Detection of age-related macular degeneration via deep learning","display_name":"Detection of age-related macular degeneration via deep learning","publication_year":2016,"publication_date":"2016-04-01","ids":{"openalex":"https://openalex.org/W2426274714","doi":"https://doi.org/10.1109/isbi.2016.7493240","mag":"2426274714"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2016.7493240","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2016.7493240","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078445265","display_name":"Philippe Burlina","orcid":"https://orcid.org/0000-0002-6353-0880"},"institutions":[{"id":"https://openalex.org/I2802946424","display_name":"Johns Hopkins University Applied Physics Laboratory","ror":"https://ror.org/029pp9z10","country_code":"US","type":"facility","lineage":["https://openalex.org/I145311948","https://openalex.org/I2802946424"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Burlina","raw_affiliation_strings":["Johns Hopkins University, Applied Physics Laboratory","School of Medicine Wilmer Eye Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University, Applied Physics Laboratory","institution_ids":["https://openalex.org/I2802946424"]},{"raw_affiliation_string":"School of Medicine Wilmer Eye Institute","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065516958","display_name":"David Freund","orcid":null},"institutions":[{"id":"https://openalex.org/I2802946424","display_name":"Johns Hopkins University Applied Physics Laboratory","ror":"https://ror.org/029pp9z10","country_code":"US","type":"facility","lineage":["https://openalex.org/I145311948","https://openalex.org/I2802946424"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. E. Freund","raw_affiliation_strings":["Johns Hopkins University, Applied Physics Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University, Applied Physics Laboratory","institution_ids":["https://openalex.org/I2802946424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050212922","display_name":"N. Joshi","orcid":"https://orcid.org/0009-0003-5844-9775"},"institutions":[{"id":"https://openalex.org/I2802946424","display_name":"Johns Hopkins University Applied Physics Laboratory","ror":"https://ror.org/029pp9z10","country_code":"US","type":"facility","lineage":["https://openalex.org/I145311948","https://openalex.org/I2802946424"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N. Joshi","raw_affiliation_strings":["Johns Hopkins University, Applied Physics Laboratory"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University, Applied Physics Laboratory","institution_ids":["https://openalex.org/I2802946424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053664973","display_name":"Yulia Wolfson","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Wolfson","raw_affiliation_strings":["School of Medicine Wilmer Eye Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine Wilmer Eye Institute","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108102931","display_name":"Neil M. Bressler","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. M. Bressler","raw_affiliation_strings":["School of Medicine Wilmer Eye Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine Wilmer Eye Institute","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":13.1041,"has_fulltext":false,"cited_by_count":139,"citation_normalized_percentile":{"value":0.99156274,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":null,"issue":null,"first_page":"184","last_page":"188"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12599","display_name":"Retinal and Optic Conditions","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/macular-degeneration","display_name":"Macular degeneration","score":0.8457958698272705},{"id":"https://openalex.org/keywords/blindness","display_name":"Blindness","score":0.6205872297286987},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.6193332076072693},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6193240284919739},{"id":"https://openalex.org/keywords/asymptomatic","display_name":"Asymptomatic","score":0.5794884562492371},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.49797987937927246},{"id":"https://openalex.org/keywords/optometry","display_name":"Optometry","score":0.4639906883239746},{"id":"https://openalex.org/keywords/deep-neural-networks","display_name":"Deep neural networks","score":0.4611170291900635},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4565451145172119},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.43603190779685974},{"id":"https://openalex.org/keywords/stage","display_name":"Stage (stratigraphy)","score":0.41593292355537415},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.35071080923080444},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.1537868082523346}],"concepts":[{"id":"https://openalex.org/C2776403814","wikidata":"https://www.wikidata.org/wiki/Q27429789","display_name":"Macular degeneration","level":2,"score":0.8457958698272705},{"id":"https://openalex.org/C2780929884","wikidata":"https://www.wikidata.org/wiki/Q737460","display_name":"Blindness","level":2,"score":0.6205872297286987},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.6193332076072693},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6193240284919739},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.5794884562492371},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.49797987937927246},{"id":"https://openalex.org/C119767625","wikidata":"https://www.wikidata.org/wiki/Q618211","display_name":"Optometry","level":1,"score":0.4639906883239746},{"id":"https://openalex.org/C2984842247","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep neural networks","level":3,"score":0.4611170291900635},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4565451145172119},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.43603190779685974},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.41593292355537415},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.35071080923080444},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1537868082523346},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2016.7493240","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2016.7493240","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4300000071525574,"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1901361661","https://openalex.org/W2037780881","https://openalex.org/W2068742492","https://openalex.org/W2073559780","https://openalex.org/W2085712747","https://openalex.org/W2123232376","https://openalex.org/W2124415048","https://openalex.org/W2134374023","https://openalex.org/W2151468273","https://openalex.org/W2598520882","https://openalex.org/W2963542991"],"related_works":["https://openalex.org/W2097753790","https://openalex.org/W2049776456","https://openalex.org/W1627705222","https://openalex.org/W4377865163","https://openalex.org/W3193857078","https://openalex.org/W2888956734","https://openalex.org/W3000197790","https://openalex.org/W4315865067","https://openalex.org/W2979433843","https://openalex.org/W3208304128"],"abstract_inverted_index":{"Age-related":[0],"macular":[1],"generation":[2],"(AMD)":[3],"-":[4,8],"when":[5],"left":[6],"untreated":[7],"is":[9,35],"the":[10,18,23,57,69,72,84,95],"main":[11],"cause":[12,62],"of":[13,20,55,71,74],"blindness":[14],"for":[15,105],"individuals":[16,31,45],"over":[17,28,32,91],"age":[19],"50.":[21],"With":[22],"US":[24],"population":[25],"now":[26],"counting":[27],"100":[29],"million":[30],"50,":[33],"it":[34],"imperative":[36],"to":[37,83],"develop":[38],"methods":[39],"that":[40,60],"can":[41,61],"effectively":[42],"determine":[43],"which":[44],"with":[46],"an":[47],"earlier,":[48],"often":[49],"asymptomatic":[50],"stage,":[51],"are":[52],"at":[53],"risk":[54],"developing":[56],"advanced":[58],"stage":[59],"severe":[63],"vision":[64],"loss.":[65],"This":[66],"paper":[67],"studies":[68],"appropriateness":[70],"transfer":[73],"image":[75,107],"features":[76],"computed":[77],"from":[78,94],"pre-trained":[79],"deep":[80],"neural":[81],"networks":[82],"problem":[85],"in":[86],"AMD":[87,106],"detection.":[88],"Tests":[89],"using":[90],"5600":[92],"images":[93],"NIH":[96],"AREDS":[97],"dataset":[98,101],"(the":[99],"largest":[100],"used":[102],"thus":[103],"far":[104],"analysis":[108],"studies)":[109],"show":[110],"good":[111],"preliminary":[112],"results":[113],"(between":[114],"nearly":[115],"92%":[116],"and":[117],"95%":[118],"accuracy).":[119]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":19},{"year":2019,"cited_by_count":19},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":1}],"updated_date":"2026-06-30T13:55:48.251075","created_date":"2025-10-10T00:00:00"}