{"id":"https://openalex.org/W1587632592","doi":"https://doi.org/10.1109/isbi.2015.7164089","title":"Direct estimation from list-mode data for reversible tracers using graphical modeling","display_name":"Direct estimation from list-mode data for reversible tracers using graphical modeling","publication_year":2015,"publication_date":"2015-04-01","ids":{"openalex":"https://openalex.org/W1587632592","doi":"https://doi.org/10.1109/isbi.2015.7164089","mag":"1587632592"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2015.7164089","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2015.7164089","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031854562","display_name":"Wentao Zhu","orcid":"https://orcid.org/0000-0001-9290-1778"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wentao Zhu","raw_affiliation_strings":["University of Southern California, Los Angeles, CA, USA","[University of Southern California Los, Angeles, CA, USA]"],"affiliations":[{"raw_affiliation_string":"University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"[University of Southern California Los, Angeles, CA, USA]","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100363340","display_name":"Ning Guo","orcid":"https://orcid.org/0000-0003-3854-0718"},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ning Guo","raw_affiliation_strings":["Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA","Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,"],"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102015401","display_name":"Bing Bai","orcid":"https://orcid.org/0009-0009-1513-0186"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bing Bai","raw_affiliation_strings":["University of Southern California, Los Angeles, CA, USA","[University of Southern California Los, Angeles, CA, USA]"],"affiliations":[{"raw_affiliation_string":"University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"[University of Southern California Los, Angeles, CA, USA]","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111367606","display_name":"Peter S. Conti","orcid":null},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter S. Conti","raw_affiliation_strings":["University of Southern California, Los Angeles, CA, USA","[University of Southern California Los, Angeles, CA, USA]"],"affiliations":[{"raw_affiliation_string":"University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"[University of Southern California Los, Angeles, CA, USA]","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054387045","display_name":"Richard M. Leahy","orcid":"https://orcid.org/0000-0002-7278-5471"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard M. Leahy","raw_affiliation_strings":["University of Southern California, Los Angeles, CA, USA","[University of Southern California Los, Angeles, CA, USA]"],"affiliations":[{"raw_affiliation_string":"University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"[University of Southern California Los, Angeles, CA, USA]","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058429770","display_name":"Quanzheng Li","orcid":"https://orcid.org/0000-0002-9651-5820"},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Quanzheng Li","raw_affiliation_strings":["Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA","Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,"],"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5031854562"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":null,"apc_paid":null,"fwci":3.1616,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.90773423,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"33","issue":null,"first_page":"1204","last_page":"1207"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11279","display_name":"Lanthanide and Transition Metal Complexes","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/monte-carlo-method","display_name":"Monte Carlo method","score":0.7097235918045044},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6749746203422546},{"id":"https://openalex.org/keywords/parametric-statistics","display_name":"Parametric statistics","score":0.6315577030181885},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.5192328095436096},{"id":"https://openalex.org/keywords/contrast","display_name":"Contrast (vision)","score":0.4995589256286621},{"id":"https://openalex.org/keywords/parametric-model","display_name":"Parametric model","score":0.4858667254447937},{"id":"https://openalex.org/keywords/mode","display_name":"Mode (computer interface)","score":0.43685266375541687},{"id":"https://openalex.org/keywords/estimation-theory","display_name":"Estimation theory","score":0.43246617913246155},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.4044072926044464},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2996084690093994},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.2777290940284729},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2567717432975769}],"concepts":[{"id":"https://openalex.org/C19499675","wikidata":"https://www.wikidata.org/wiki/Q232207","display_name":"Monte Carlo method","level":2,"score":0.7097235918045044},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6749746203422546},{"id":"https://openalex.org/C117251300","wikidata":"https://www.wikidata.org/wiki/Q1849855","display_name":"Parametric statistics","level":2,"score":0.6315577030181885},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5192328095436096},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.4995589256286621},{"id":"https://openalex.org/C24574437","wikidata":"https://www.wikidata.org/wiki/Q7135228","display_name":"Parametric model","level":3,"score":0.4858667254447937},{"id":"https://openalex.org/C48677424","wikidata":"https://www.wikidata.org/wiki/Q6888088","display_name":"Mode (computer interface)","level":2,"score":0.43685266375541687},{"id":"https://openalex.org/C167928553","wikidata":"https://www.wikidata.org/wiki/Q1376021","display_name":"Estimation theory","level":2,"score":0.43246617913246155},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.4044072926044464},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2996084690093994},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.2777290940284729},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2567717432975769},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2015.7164089","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2015.7164089","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1973172749","https://openalex.org/W1974851349","https://openalex.org/W1982039560","https://openalex.org/W1987035674","https://openalex.org/W2005277084","https://openalex.org/W2016987771","https://openalex.org/W2051228374","https://openalex.org/W2075468186","https://openalex.org/W2080951328","https://openalex.org/W2084090004","https://openalex.org/W2111352290","https://openalex.org/W2152788151","https://openalex.org/W2162905116","https://openalex.org/W6683958384"],"related_works":["https://openalex.org/W2289718384","https://openalex.org/W1995675544","https://openalex.org/W2509524819","https://openalex.org/W3127866798","https://openalex.org/W2068427817","https://openalex.org/W4294845631","https://openalex.org/W2538333368","https://openalex.org/W2952090425","https://openalex.org/W2012121796","https://openalex.org/W2043546065"],"abstract_inverted_index":{"We":[0,24],"propose":[1],"a":[2,26,89],"novel":[3],"method":[4,70],"to":[5,32,36,48,54],"directly":[6],"estimate":[7],"parametric":[8],"images":[9],"from":[10,43],"listmode":[11],"PET":[12],"data":[13],"for":[14],"reversible":[15],"tracers":[16],"based":[17,91],"on":[18],"an":[19],"inhomogeneous":[20],"Poisson":[21],"process":[22],"model.":[23],"use":[25],"relative":[27],"equilibrium":[28],"graphical":[29],"model,":[30],"similar":[31],"the":[33,38,49,56,59,72,75],"Logan":[34],"plot,":[35],"linearize":[37],"problem.":[39,61],"A":[40],"static":[41],"sinogram":[42,90],"time":[44],"of":[45,58,74],"tracer":[46],"injection":[47],"steady":[50],"state":[51],"is":[52],"incorporated":[53],"improve":[55],"ill-conditioning":[57],"estimation":[60,76,93],"Cramer-Rao":[62],"analysis":[63],"and":[64,78,83],"Monte-Carlo":[65],"simulation":[66],"demonstrate":[67],"that":[68],"our":[69],"improves":[71],"conditioning":[73],"problem":[77],"provides":[79],"higher":[80],"contrast":[81],"recovery":[82],"smaller":[84],"standard":[85],"deviation":[86],"compared":[87],"with":[88],"direct":[92],"approach.":[94]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":11}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}