{"id":"https://openalex.org/W1545392483","doi":"https://doi.org/10.1109/isbi.2015.7163841","title":"Symmetry-based mitosis detection in time-lapse microscopy","display_name":"Symmetry-based mitosis detection in time-lapse microscopy","publication_year":2015,"publication_date":"2015-04-01","ids":{"openalex":"https://openalex.org/W1545392483","doi":"https://doi.org/10.1109/isbi.2015.7163841","mag":"1545392483"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2015.7163841","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2015.7163841","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031303236","display_name":"Topaz Gilad","orcid":null},"institutions":[{"id":"https://openalex.org/I124227911","display_name":"Ben-Gurion University of the Negev","ror":"https://ror.org/05tkyf982","country_code":"IL","type":"education","lineage":["https://openalex.org/I124227911"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Topaz Gilad","raw_affiliation_strings":["Electrical and Computer Engineering Department, Ben-Gurion University of the Negev"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Electrical and Computer Engineering Department, Ben-Gurion University of the Negev","institution_ids":["https://openalex.org/I124227911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059045145","display_name":"Mark\u2010Anthony Bray","orcid":"https://orcid.org/0000-0002-9748-3592"},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark-Anthony Bray","raw_affiliation_strings":["Imaging Platform, The Broad Institute of Harvard and MIT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imaging Platform, The Broad Institute of Harvard and MIT","institution_ids":["https://openalex.org/I107606265"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052473265","display_name":"Anne E. Carpenter","orcid":"https://orcid.org/0000-0003-1555-8261"},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anne E. Carpenter","raw_affiliation_strings":["Imaging Platform, The Broad Institute of Harvard and MIT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imaging Platform, The Broad Institute of Harvard and MIT","institution_ids":["https://openalex.org/I107606265"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063831080","display_name":"Tammy Riklin Raviv","orcid":"https://orcid.org/0000-0003-2532-5875"},"institutions":[{"id":"https://openalex.org/I124227911","display_name":"Ben-Gurion University of the Negev","ror":"https://ror.org/05tkyf982","country_code":"IL","type":"education","lineage":["https://openalex.org/I124227911"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Tammy Riklin Raviv","raw_affiliation_strings":["Electrical and Computer Engineering Department, Ben-Gurion University of the Negev"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Electrical and Computer Engineering Department, Ben-Gurion University of the Negev","institution_ids":["https://openalex.org/I124227911"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.3028,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.97318008,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"164","last_page":"167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.6398485898971558},{"id":"https://openalex.org/keywords/symmetry","display_name":"Symmetry (geometry)","score":0.591225266456604},{"id":"https://openalex.org/keywords/mitosis","display_name":"Mitosis","score":0.56875079870224},{"id":"https://openalex.org/keywords/bilateral-symmetry","display_name":"Bilateral symmetry","score":0.4197840690612793},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3791276216506958},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.3507625162601471},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.35052841901779175},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.17120254039764404},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.15097960829734802},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.14237168431282043},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12534573674201965},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.09754514694213867}],"concepts":[{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.6398485898971558},{"id":"https://openalex.org/C2779886137","wikidata":"https://www.wikidata.org/wiki/Q21030012","display_name":"Symmetry (geometry)","level":2,"score":0.591225266456604},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.56875079870224},{"id":"https://openalex.org/C2985276286","wikidata":"https://www.wikidata.org/wiki/Q598159","display_name":"Bilateral symmetry","level":2,"score":0.4197840690612793},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3791276216506958},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3507625162601471},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.35052841901779175},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.17120254039764404},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15097960829734802},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.14237168431282043},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12534573674201965},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.09754514694213867},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2015.7163841","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2015.7163841","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7599999904632568,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W22155560","https://openalex.org/W1987869189","https://openalex.org/W2011604289","https://openalex.org/W2019607023","https://openalex.org/W2121469024","https://openalex.org/W2122502232","https://openalex.org/W2141273399","https://openalex.org/W2146777799","https://openalex.org/W2171074980","https://openalex.org/W6655193779","https://openalex.org/W6678131937"],"related_works":["https://openalex.org/W2171314435","https://openalex.org/W2073604728","https://openalex.org/W1574787199","https://openalex.org/W2164293324","https://openalex.org/W2157987945","https://openalex.org/W2077024184","https://openalex.org/W2414337799","https://openalex.org/W2005130062","https://openalex.org/W4233444611","https://openalex.org/W203882189"],"abstract_inverted_index":{"Providing":[0],"a":[1,81],"general":[2,70],"framework":[3],"for":[4,139,165],"mitosis":[5,162],"detection":[6,85,163],"is":[7,25,146],"challenging.":[8],"The":[9,44],"variability":[10],"of":[11,22,55,58,91,125,153,155,159],"the":[12,20,29,53,89,92,104,109,115,140,150],"visual":[13],"traits":[14],"and":[15,36,64,96],"temporal":[16],"features":[17,60],"which":[18,114],"classify":[19],"event":[21,84,145],"cell":[23,31,94,100],"division":[24],"huge":[26],"due":[27],"to":[28,69,76,133],"numerous":[30],"types,":[32],"perturbations,":[33],"imaging":[34,41],"techniques":[35,49],"protocols":[37],"used":[38,46],"in":[39],"microscopy":[40,169],"analysis":[42],"studies.":[43],"commonly":[45],"machine":[47],"learning":[48],"are":[50,74,119],"based":[51,129,148],"on":[52,130,149],"extraction":[54],"comprehensive":[56],"sets":[57],"discriminative":[59],"from":[61],"labeled":[62],"examples":[63],"therefore":[65],"do":[66],"not":[67],"apply":[68],"cases":[71],"as":[72],"they":[73],"restricted":[75],"trained":[77],"datasets.":[78],"We":[79],"present":[80],"robust":[82],"mitotic":[83],"algorithm":[86],"that":[87],"accommodates":[88],"difficulty":[90],"different":[93,167],"appearances":[95],"dynamics.":[97],"Addressing":[98],"symmetrical":[99],"divisions,":[101],"we":[102,137],"consider":[103],"anaphase":[105],"stage,":[106],"immediately":[107],"after":[108],"DNA":[110],"material":[111],"divides,":[112],"at":[113],"two":[116],"daughter":[117,127],"cells":[118],"approximately":[120],"identical.":[121],"Having":[122],"detected":[123,147],"pairs":[124],"candidate":[126,157],"cells,":[128,136],"their":[131],"association":[132],"potential":[134],"mother":[135],"look":[138],"respective":[141],"symmetry":[142,154],"axes.":[143],"Mitotic":[144],"calculated":[151],"measure":[152],"each":[156],"pair":[158],"cells.":[160],"Promising":[161],"results":[164],"four":[166],"time-lapse":[168],"datasets":[170],"were":[171],"obtained.":[172]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-08-06T08:24:18.245995","created_date":"2025-10-10T00:00:00"}