{"id":"https://openalex.org/W2074776458","doi":"https://doi.org/10.1109/isbi.2014.6867916","title":"Multi-scale non-local means with shape prior for enhancement of cell membrane images","display_name":"Multi-scale non-local means with shape prior for enhancement of cell membrane images","publication_year":2014,"publication_date":"2014-04-01","ids":{"openalex":"https://openalex.org/W2074776458","doi":"https://doi.org/10.1109/isbi.2014.6867916","mag":"2074776458"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2014.6867916","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2014.6867916","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072118567","display_name":"Cheng\u2010Jin Du","orcid":"https://orcid.org/0000-0002-9879-9409"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Cheng-Jin Du","raw_affiliation_strings":["Warwick Systems Biology Centre, University of Warwick, Coventry, UK","Warwick Systems Biology Centre, University of Warwick, Coventry, CV4 7AL, UK, UK"],"affiliations":[{"raw_affiliation_string":"Warwick Systems Biology Centre, University of Warwick, Coventry, UK","institution_ids":["https://openalex.org/I39555362"]},{"raw_affiliation_string":"Warwick Systems Biology Centre, University of Warwick, Coventry, CV4 7AL, UK, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111864213","display_name":"Richard A. Tyson","orcid":null},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard Tyson","raw_affiliation_strings":["Warwick Systems Biology Centre, University of Warwick, Coventry, UK","Warwick Systems Biology Centre, University of Warwick, Coventry CV4 7AL, UK,"],"affiliations":[{"raw_affiliation_string":"Warwick Systems Biology Centre, University of Warwick, Coventry, UK","institution_ids":["https://openalex.org/I39555362"]},{"raw_affiliation_string":"Warwick Systems Biology Centre, University of Warwick, Coventry CV4 7AL, UK,","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063574896","display_name":"Emil Rozbicki","orcid":null},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emil Rozbicki","raw_affiliation_strings":["College of Life Sciences, University of Dundee, Dundee, UK","College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK"],"affiliations":[{"raw_affiliation_string":"College of Life Sciences, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307"]},{"raw_affiliation_string":"College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043042507","display_name":"Cornelis J. Weijer","orcid":"https://orcid.org/0000-0003-2192-8150"},"institutions":[{"id":"https://openalex.org/I177639307","display_name":"University of Dundee","ror":"https://ror.org/03h2bxq36","country_code":"GB","type":"education","lineage":["https://openalex.org/I177639307"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Cornells J. Weijer","raw_affiliation_strings":["College of Life Sciences, University of Dundee, Dundee, UK","College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK"],"affiliations":[{"raw_affiliation_string":"College of Life Sciences, University of Dundee, Dundee, UK","institution_ids":["https://openalex.org/I177639307"]},{"raw_affiliation_string":"College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK","institution_ids":["https://openalex.org/I177639307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074864006","display_name":"Till Bretschneider","orcid":"https://orcid.org/0000-0002-5317-603X"},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Till Bretschneider","raw_affiliation_strings":["Warwick Systems Biology Centre, University of Warwick, Coventry, UK","Warwick Systems Biology Centre, University of Warwick, Coventry CV4 7AL, UK,"],"affiliations":[{"raw_affiliation_string":"Warwick Systems Biology Centre, University of Warwick, Coventry, UK","institution_ids":["https://openalex.org/I39555362"]},{"raw_affiliation_string":"Warwick Systems Biology Centre, University of Warwick, Coventry CV4 7AL, UK,","institution_ids":["https://openalex.org/I39555362"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5072118567"],"corresponding_institution_ids":["https://openalex.org/I39555362"],"apc_list":null,"apc_paid":null,"fwci":0.2472,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.607043,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"493","last_page":"496"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10688","display_name":"Image and Signal Denoising Methods","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10688","display_name":"Image and Signal Denoising Methods","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anisotropic-diffusion","display_name":"Anisotropic diffusion","score":0.8471034169197083},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5680217742919922},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5668448209762573},{"id":"https://openalex.org/keywords/anisotropy","display_name":"Anisotropy","score":0.5425262451171875},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5256151556968689},{"id":"https://openalex.org/keywords/diffusion","display_name":"Diffusion","score":0.5116272568702698},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.4891069531440735},{"id":"https://openalex.org/keywords/noise-reduction","display_name":"Noise reduction","score":0.48447370529174805},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.4696240723133087},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.46645990014076233},{"id":"https://openalex.org/keywords/image-enhancement","display_name":"Image enhancement","score":0.462606281042099},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.4618702232837677},{"id":"https://openalex.org/keywords/structure-tensor","display_name":"Structure tensor","score":0.4561336636543274},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.44590675830841064},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4432200789451599},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4411258399486542},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.4389798939228058},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.3254740834236145},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2302461862564087},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.15545222163200378}],"concepts":[{"id":"https://openalex.org/C203504353","wikidata":"https://www.wikidata.org/wiki/Q4765461","display_name":"Anisotropic diffusion","level":3,"score":0.8471034169197083},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5680217742919922},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5668448209762573},{"id":"https://openalex.org/C85725439","wikidata":"https://www.wikidata.org/wiki/Q466686","display_name":"Anisotropy","level":2,"score":0.5425262451171875},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5256151556968689},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.5116272568702698},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.4891069531440735},{"id":"https://openalex.org/C163294075","wikidata":"https://www.wikidata.org/wiki/Q581861","display_name":"Noise reduction","level":2,"score":0.48447370529174805},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.4696240723133087},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.46645990014076233},{"id":"https://openalex.org/C3017601658","wikidata":"https://www.wikidata.org/wiki/Q545981","display_name":"Image enhancement","level":3,"score":0.462606281042099},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.4618702232837677},{"id":"https://openalex.org/C113315163","wikidata":"https://www.wikidata.org/wiki/Q7625159","display_name":"Structure tensor","level":3,"score":0.4561336636543274},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.44590675830841064},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4432200789451599},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4411258399486542},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.4389798939228058},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3254740834236145},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2302461862564087},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15545222163200378},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/isbi.2014.6867916","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2014.6867916","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmh:oai:discovery.dundee.ac.uk:openaire_cris_publications/92e784d2-0cfb-4358-bb38-ce011f9cefe4","is_oa":false,"landing_page_url":"https://discovery.dundee.ac.uk/en/publications/92e784d2-0cfb-4358-bb38-ce011f9cefe4","pdf_url":null,"source":{"id":"https://openalex.org/S4306400523","display_name":"Discovery Research Portal (University of Dundee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I177639307","host_organization_name":"University of Dundee","host_organization_lineage":["https://openalex.org/I177639307"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Du, C-J, Tyson, R, Rozbicki, E, Weijer, C J & Bretschneider, T 2014, Multi-scale non-local means with shape prior for enhancement of cell membrane images. in 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014 : Proceedings. IEEE, pp. 493-496, 2014 IEEE International Symposium on Biomedical Imaging, Beijing, China, 29/04/14. https://doi.org/10.1109/ISBI.2014.6867916","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G6582887679","display_name":null,"funder_award_id":"BB/I008209/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1562826660","https://openalex.org/W1993296994","https://openalex.org/W1993465480","https://openalex.org/W2006269342","https://openalex.org/W2108944658","https://openalex.org/W2128000934","https://openalex.org/W2136396015","https://openalex.org/W2168896212","https://openalex.org/W4213367101","https://openalex.org/W7009755511"],"related_works":["https://openalex.org/W2262332166","https://openalex.org/W2373529328","https://openalex.org/W2319782925","https://openalex.org/W2386523173","https://openalex.org/W2475096862","https://openalex.org/W1966786995","https://openalex.org/W2154534640","https://openalex.org/W2379232376","https://openalex.org/W2046976899","https://openalex.org/W2157622201"],"abstract_inverted_index":{"Light":[0],"sheet":[1],"microscopy":[2],"allows":[3],"rapid":[4],"optical":[5],"sectioning":[6],"of":[7,19,35,97],"whole":[8],"chicken":[9],"embryos":[10],"during":[11],"early":[12],"development,":[13],"visualizing":[14],"cells":[15],"through":[16],"transgenic":[17],"expression":[18],"a":[20,47],"fluorescent":[21],"cell":[22,43],"membrane":[23],"label.":[24],"Low":[25],"signal-to-noise":[26],"ratios":[27],"and":[28,69,77],"large":[29],"variability":[30],"in":[31,41],"intensity":[32],"make":[33],"segmentation":[34],"these":[36],"images":[37],"difficult,":[38],"often":[39],"resulting":[40],"discontinuous":[42],"edges.":[44],"We":[45],"propose":[46],"multi-scale":[48,86],"non-local":[49,111],"means":[50],"with":[51],"shape":[52],"prior":[53],"(MS-NLM-SP)":[54],"method":[55],"for":[56],"image":[57,112],"enhancement,":[58],"which":[59],"takes":[60],"into":[61,110],"account":[62],"cell-specific":[63,108],"characteristics,":[64],"such":[65],"as":[66],"size,":[67],"geometry,":[68],"periodicity.":[70],"Investigating":[71],"theoretical":[72],"connections":[73],"between":[74],"our":[75],"approach":[76],"anisotropic":[78,100],"diffusion":[79],"reveals":[80],"that":[81,106],"the":[82,94],"first":[83],"step,":[84],"detail-enhanced":[85],"representation,":[87],"corresponds":[88],"to":[89],"selective":[90],"backward":[91],"diffusion,":[92],"while":[93],"second":[95],"step":[96],"MS-NLM-SP":[98],"resembles":[99],"forward":[101],"diffusion.":[102],"Experimental":[103],"results":[104],"show":[105],"incorporating":[107],"features":[109],"denoising":[113],"methods":[114],"improves":[115],"subsequent":[116],"segmentation.":[117]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}