{"id":"https://openalex.org/W2083663720","doi":"https://doi.org/10.1109/isbi.2013.6556427","title":"Morphometry for early monitoring of treatment response in rheumatoid arthritis","display_name":"Morphometry for early monitoring of treatment response in rheumatoid arthritis","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W2083663720","doi":"https://doi.org/10.1109/isbi.2013.6556427","mag":"2083663720","pmid":"https://pubmed.ncbi.nlm.nih.gov/24026194"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2013.6556427","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2013.6556427","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE 10th International Symposium on Biomedical Imaging","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048206294","display_name":"Anand A. Joshi","orcid":"https://orcid.org/0000-0002-9582-3848"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Anand A. Joshi","raw_affiliation_strings":["Signal and Image Processing Institute, University of Southern California, Los Angeles, CA 90089, USA","[Signal & Image Process. Inst., Univ. of Southern California, Los Angeles, CA, USA]"],"affiliations":[{"raw_affiliation_string":"Signal and Image Processing Institute, University of Southern California, Los Angeles, CA 90089, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"[Signal & Image Process. Inst., Univ. of Southern California, Los Angeles, CA, USA]","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054387045","display_name":"Richard M. Leahy","orcid":"https://orcid.org/0000-0002-7278-5471"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard M. Leahy","raw_affiliation_strings":["Signal and Image Processing Institute, University of Southern California, Los Angeles, CA, USA","[Signal & Image Process. Inst., Univ. of Southern California, Los Angeles, CA, USA]"],"affiliations":[{"raw_affiliation_string":"Signal and Image Processing Institute, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"[Signal & Image Process. Inst., Univ. of Southern California, Los Angeles, CA, USA]","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047816435","display_name":"Ramsey D. Badawi","orcid":"https://orcid.org/0000-0002-9769-0292"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ramsey D. Badawi","raw_affiliation_strings":["Radiology, UC Davis School of Medicine, Sacramento, CA, USA","Sch. of Med., Radiol., UC Davis, Sacramento, CA, USA"],"affiliations":[{"raw_affiliation_string":"Radiology, UC Davis School of Medicine, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Sch. of Med., Radiol., UC Davis, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041539465","display_name":"Abhijit J. Chaudhari","orcid":"https://orcid.org/0000-0002-4211-1900"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Abhijit J. Chaudhari","raw_affiliation_strings":["Radiology, UC Davis School of Medicine, Sacramento, CA, USA","Sch. of Med., Radiol., UC Davis, Sacramento, CA, USA"],"affiliations":[{"raw_affiliation_string":"Radiology, UC Davis School of Medicine, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Sch. of Med., Radiol., UC Davis, Sacramento, CA, USA","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5048206294"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":null,"apc_paid":null,"fwci":0.2521,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.62095991,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"34","issue":null,"first_page":"121","last_page":"124"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9064000248908997,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"Rheumatoid arthritis","score":0.841849684715271},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.8235690593719482},{"id":"https://openalex.org/keywords/wrist","display_name":"Wrist","score":0.666178286075592},{"id":"https://openalex.org/keywords/arthritis","display_name":"Arthritis","score":0.5305845141410828},{"id":"https://openalex.org/keywords/clinical-trial","display_name":"Clinical trial","score":0.5141521096229553},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.4493468701839447},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.34387558698654175},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.2845900058746338}],"concepts":[{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.841849684715271},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8235690593719482},{"id":"https://openalex.org/C2778216619","wikidata":"https://www.wikidata.org/wiki/Q185706","display_name":"Wrist","level":2,"score":0.666178286075592},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.5305845141410828},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5141521096229553},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4493468701839447},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34387558698654175},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2845900058746338}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi.2013.6556427","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2013.6556427","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE 10th International Symposium on Biomedical Imaging","raw_type":"proceedings-article"},{"id":"pmid:24026194","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24026194","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:europepmc.org:2759143","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3767479","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1549923931","https://openalex.org/W1933181695","https://openalex.org/W2013879982","https://openalex.org/W2021787435","https://openalex.org/W2065563091","https://openalex.org/W2113110582","https://openalex.org/W2117661333","https://openalex.org/W2144929975","https://openalex.org/W2148522252","https://openalex.org/W2335898267","https://openalex.org/W2340084730","https://openalex.org/W2485542973","https://openalex.org/W6640458814","https://openalex.org/W6703412513"],"related_works":["https://openalex.org/W2406926056","https://openalex.org/W2185550546","https://openalex.org/W110334421","https://openalex.org/W2416097977","https://openalex.org/W2048493693","https://openalex.org/W2559360246","https://openalex.org/W1996668300","https://openalex.org/W2028766184","https://openalex.org/W2993678931","https://openalex.org/W1501007924"],"abstract_inverted_index":{"New":[0],"aggressive":[1],"therapeutic":[2],"options":[3],"have":[4],"recently":[5],"become":[6],"available":[7],"to":[8,43,51,53,75,78,88,117,120,132,137],"treat":[9],"inflammatory":[10],"arthritis":[11,15,148],"(IA)":[12],"and":[13,48,59,72],"rheumatoid":[14],"in":[16,29,96,124,140],"particular.":[17],"These":[18],"treatments":[19],"not":[20],"only":[21],"control":[22],"joint":[23],"destruction,":[24],"they":[25],"may":[26],"also":[27],"aid":[28],"new":[30,134,147],"bone":[31,125],"formation":[32],"at":[33],"sites":[34],"of":[35,39,64,70,93,146],"eroded":[36],"bone.":[37],"Separation":[38],"non-responders":[40],"from":[41],"responders":[42],"these":[44],"treatments,":[45],"is":[46,49],"critical,":[47],"known":[50,74],"lead":[52],"reduced":[54],"disease":[55],"burden,":[56],"toxicity,":[57],"side-effects":[58],"overall":[60],"cost.":[61],"The":[62,101],"bones":[63,95],"the":[65,112,144],"wrist":[66,94],"are":[67,73],"early":[68,122],"targets":[69],"IA":[71,97],"show":[76],"response":[77],"therapy":[79],"early.":[80],"In":[81],"this":[82],"paper,":[83],"we":[84],"develop":[85],"a":[86],"method":[87,102,114],"quantify":[89],"point-wise":[90],"erosive":[91],"changes":[92,123],"patients":[98],"undergoing":[99],"treatment.":[100],"employs":[103],"3D":[104],"registration-based":[105],"morphometric":[106],"analysis.":[107],"Our":[108],"results":[109],"indicate":[110],"that":[111],"proposed":[113],"has":[115,130],"potential":[116,131],"improve":[118],"sensitivity":[119],"small,":[121],"erosion":[126],"status.":[127],"This":[128],"study":[129],"provide":[133],"imaging":[135],"biomarkers":[136],"be":[138],"used":[139],"clinical":[141],"trials":[142],"evaluating":[143],"efficacy":[145],"drugs.":[149]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}