{"id":"https://openalex.org/W2056218412","doi":"https://doi.org/10.1109/isbi.2012.6235764","title":"Segmentation of serial MRI of TBI patients using personalized atlas construction and topological change estimation","display_name":"Segmentation of serial MRI of TBI patients using personalized atlas construction and topological change estimation","publication_year":2012,"publication_date":"2012-05-01","ids":{"openalex":"https://openalex.org/W2056218412","doi":"https://doi.org/10.1109/isbi.2012.6235764","mag":"2056218412","pmid":"https://pubmed.ncbi.nlm.nih.gov/23999192"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2012.6235764","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2012.6235764","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100408128","display_name":"Bo Wang","orcid":"https://orcid.org/0000-0002-7233-0477"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210090176","display_name":"Institute of Computing Technology","ror":"https://ror.org/0090r4d87","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210090176"]},{"id":"https://openalex.org/I4210145671","display_name":"Advanced Imaging Research (United States)","ror":"https://ror.org/047c3xe48","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145671"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Bo Wang","raw_affiliation_strings":["Scientific Computing and Imaging Institute, University of Utah ; School of Computing, University of Utah","[Scientific Computing and Imaging Institute, University of Utah]"],"affiliations":[{"raw_affiliation_string":"Scientific Computing and Imaging Institute, University of Utah ; School of Computing, University of Utah","institution_ids":["https://openalex.org/I4210090176"]},{"raw_affiliation_string":"[Scientific Computing and Imaging Institute, University of Utah]","institution_ids":["https://openalex.org/I4210145671","https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071251239","display_name":"Marcel Prastawa","orcid":"https://orcid.org/0000-0002-0278-9637"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210145671","display_name":"Advanced Imaging Research (United States)","ror":"https://ror.org/047c3xe48","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marcel Prastawa","raw_affiliation_strings":["Scientific Computing and Imaging Institute, School of Computing, University of Utah, USA","[Scientific Computing and Imaging Institute, University of Utah]"],"affiliations":[{"raw_affiliation_string":"Scientific Computing and Imaging Institute, School of Computing, University of Utah, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"[Scientific Computing and Imaging Institute, University of Utah]","institution_ids":["https://openalex.org/I4210145671","https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017642893","display_name":"Suyash P. Awate","orcid":"https://orcid.org/0000-0002-4945-9539"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210145671","display_name":"Advanced Imaging Research (United States)","ror":"https://ror.org/047c3xe48","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suyash P. Awate","raw_affiliation_strings":["Scientific Computing and Imaging Institute, School of Computing, University of Utah, USA","[Scientific Computing and Imaging Institute, University of Utah]"],"affiliations":[{"raw_affiliation_string":"Scientific Computing and Imaging Institute, School of Computing, University of Utah, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"[Scientific Computing and Imaging Institute, University of Utah]","institution_ids":["https://openalex.org/I4210145671","https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059896728","display_name":"Andrei Irimia","orcid":null},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrei Irimia","raw_affiliation_strings":["Laboratory of Neuro Imaging, University of California, Los Angeles, USA","Laboratory of Neuro Imaging, University of California at Los Angeles"],"affiliations":[{"raw_affiliation_string":"Laboratory of Neuro Imaging, University of California, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Laboratory of Neuro Imaging, University of California at Los Angeles","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083570938","display_name":"Micah C. Chambers","orcid":null},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Micah C Chambers","raw_affiliation_strings":["Laboratory of Neuro Imaging, University of California, Los Angeles, USA","Laboratory of Neuro Imaging, University of California at Los Angeles"],"affiliations":[{"raw_affiliation_string":"Laboratory of Neuro Imaging, University of California, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Laboratory of Neuro Imaging, University of California at Los Angeles","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063250341","display_name":"Paul Vespa","orcid":"https://orcid.org/0000-0003-0936-9501"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul M. Vespa","raw_affiliation_strings":["Brain Injury Research Center, University of California, Los Angeles, USA","Brain Injury Research Center, University of California at Los Angeles"],"affiliations":[{"raw_affiliation_string":"Brain Injury Research Center, University of California, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Brain Injury Research Center, University of California at Los Angeles","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085358934","display_name":"John D. Van Horn","orcid":"https://orcid.org/0000-0003-1537-0816"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John D. van Horn","raw_affiliation_strings":["Laboratory of Neuro Imaging, University of California, Los Angeles, USA","Laboratory of Neuro Imaging, University of California at Los Angeles"],"affiliations":[{"raw_affiliation_string":"Laboratory of Neuro Imaging, University of California, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Laboratory of Neuro Imaging, University of California at Los Angeles","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010769610","display_name":"Guido Gerig","orcid":"https://orcid.org/0000-0002-9547-6233"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210145671","display_name":"Advanced Imaging Research (United States)","ror":"https://ror.org/047c3xe48","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guido Gerig","raw_affiliation_strings":["Scientific Computing and Imaging Institute, School of Computing, University of Utah, USA","[Scientific Computing and Imaging Institute, University of Utah]"],"affiliations":[{"raw_affiliation_string":"Scientific Computing and Imaging Institute, School of Computing, University of Utah, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"[Scientific Computing and Imaging Institute, University of Utah]","institution_ids":["https://openalex.org/I4210145671","https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5100408128"],"corresponding_institution_ids":["https://openalex.org/I223532165","https://openalex.org/I4210090176","https://openalex.org/I4210145671"],"apc_list":null,"apc_paid":null,"fwci":2.0722,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.86170202,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"1152","last_page":"1155"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9919000267982483,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atlas","display_name":"Atlas (anatomy)","score":0.8072558045387268},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.7952092885971069},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6129947304725647},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.6050878167152405},{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"Traumatic brain injury","score":0.5391185283660889},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.49211257696151733},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4769022464752197},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.465564489364624},{"id":"https://openalex.org/keywords/market-segmentation","display_name":"Market segmentation","score":0.4595455527305603},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.4193729758262634},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3774149715900421},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.35124891996383667},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.34556281566619873},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.22629421949386597},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.12623366713523865},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.12010449171066284},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.10220921039581299}],"concepts":[{"id":"https://openalex.org/C2776673561","wikidata":"https://www.wikidata.org/wiki/Q655357","display_name":"Atlas (anatomy)","level":2,"score":0.8072558045387268},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.7952092885971069},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6129947304725647},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6050878167152405},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.5391185283660889},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.49211257696151733},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4769022464752197},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.465564489364624},{"id":"https://openalex.org/C125308379","wikidata":"https://www.wikidata.org/wiki/Q363057","display_name":"Market segmentation","level":2,"score":0.4595455527305603},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.4193729758262634},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3774149715900421},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.35124891996383667},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.34556281566619873},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22629421949386597},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.12623366713523865},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.12010449171066284},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.10220921039581299},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi.2012.6235764","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2012.6235764","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmid:23999192","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23999192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:europepmc.org:2747513","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3758244","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.75,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1581901784","https://openalex.org/W1980114101","https://openalex.org/W1998523279","https://openalex.org/W2013930726","https://openalex.org/W2020011602","https://openalex.org/W2022544980","https://openalex.org/W2050687114","https://openalex.org/W2076846692","https://openalex.org/W2130686832","https://openalex.org/W2139109897","https://openalex.org/W2736091234","https://openalex.org/W2914320392","https://openalex.org/W6634673315"],"related_works":["https://openalex.org/W2011187995","https://openalex.org/W2314146950","https://openalex.org/W2373521488","https://openalex.org/W2803101231","https://openalex.org/W4284509","https://openalex.org/W606911313","https://openalex.org/W4229506690","https://openalex.org/W638747717","https://openalex.org/W4243557525","https://openalex.org/W1489383734"],"abstract_inverted_index":{"Traumatic":[0],"brain":[1,44],"injury":[2],"(TBI)":[3],"due":[4,63],"to":[5,64,146],"falls,":[6],"car":[7],"accidents,":[8],"and":[9,19,74,77],"warfare":[10],"affects":[11],"millions":[12],"of":[13,21,67,97,106,118],"people":[14],"annually.":[15],"Determining":[16],"personalized":[17,50,112],"therapy":[18],"assessment":[20],"treatment":[22],"efficacy":[23],"can":[24],"substantially":[25],"benefit":[26],"from":[27],"longitudinal":[28,43],"(4D)":[29],"magnetic":[30],"resonance":[31],"imaging":[32],"(MRI).":[33],"In":[34],"this":[35,83,119],"paper,":[36],"we":[37],"propose":[38],"a":[39,87],"method":[40,101,136],"for":[41],"segmenting":[42],"MR":[45,122],"images":[46,54,123],"with":[47,55,110,124],"TBI":[48,56,125],"using":[49],"atlas":[51,89],"construction.":[52],"Longitudinal":[53],"typically":[57],"present":[58],"topological":[59,98,107],"changes":[60,108],"over":[61],"time":[62],"the":[65,68,78,95,104,111,116],"effect":[66,96],"impact":[69],"force":[70],"on":[71,121],"tissue,":[72],"skull,":[73],"blood":[75],"vessels":[76],"recovery":[79],"process.":[80],"We":[81,114],"address":[82],"issue":[84],"by":[85,131],"defining":[86],"novel":[88],"construction":[90],"scheme":[91],"that":[92,126,137],"explicitly":[93],"models":[94],"changes.":[99],"Our":[100],"automatically":[102],"estimates":[103],"probability":[105],"jointly":[109],"atlas.":[113],"demonstrate":[115],"effectiveness":[117],"approach":[120],"also":[127],"have":[128],"been":[129],"segmented":[130],"human":[132],"raters,":[133],"where":[134],"our":[135],"integrates":[138],"4D":[139],"information":[140],"yields":[141],"improved":[142],"validation":[143],"measures":[144],"compared":[145],"temporally":[147],"independent":[148],"segmentations.":[149]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}