{"id":"https://openalex.org/W2117214399","doi":"https://doi.org/10.1109/isbi.2012.6235619","title":"Support vector machine (SVM) active learning for automated Glioblastoma segmentation","display_name":"Support vector machine (SVM) active learning for automated Glioblastoma segmentation","publication_year":2012,"publication_date":"2012-05-01","ids":{"openalex":"https://openalex.org/W2117214399","doi":"https://doi.org/10.1109/isbi.2012.6235619","mag":"2117214399"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2012.6235619","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2012.6235619","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046617410","display_name":"Po-Chyi Su","orcid":"https://orcid.org/0000-0002-7457-8409"},"institutions":[{"id":"https://openalex.org/I17145004","display_name":"Northwestern Polytechnical University","ror":"https://ror.org/01y0j0j86","country_code":"CN","type":"education","lineage":["https://openalex.org/I17145004"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210109259","display_name":"Methodist Hospital","ror":"https://ror.org/01r5p9y80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802827176","https://openalex.org/I4210109259"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Po Su","raw_affiliation_strings":["Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Medical College of Cornell University, Houston, TX, USA","School of Automation, Northwestern Polytechnical University, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Medical College of Cornell University, Houston, TX, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210109259"]},{"raw_affiliation_string":"School of Automation, Northwestern Polytechnical University, China","institution_ids":["https://openalex.org/I17145004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100768668","display_name":"Zhong Xue","orcid":"https://orcid.org/0000-0003-3207-0890"},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210109259","display_name":"Methodist Hospital","ror":"https://ror.org/01r5p9y80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802827176","https://openalex.org/I4210109259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhong Xue","raw_affiliation_strings":["Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Medical College of Cornell University, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Medical College of Cornell University, Houston, TX, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210109259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110967133","display_name":"Linda Chi","orcid":null},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linda Chi","raw_affiliation_strings":["Department of Diagnostic Radiology, M.D. Anderson Cancer Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Radiology, M.D. Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103214860","display_name":"Jianhua Yang","orcid":"https://orcid.org/0000-0001-8765-8662"},"institutions":[{"id":"https://openalex.org/I17145004","display_name":"Northwestern Polytechnical University","ror":"https://ror.org/01y0j0j86","country_code":"CN","type":"education","lineage":["https://openalex.org/I17145004"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianhua Yang","raw_affiliation_strings":["School of Automation, Northwestern Polytechnical University, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Automation, Northwestern Polytechnical University, China","institution_ids":["https://openalex.org/I17145004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015077092","display_name":"Stephen T.C. Wong","orcid":"https://orcid.org/0000-0001-9188-6502"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210109259","display_name":"Methodist Hospital","ror":"https://ror.org/01r5p9y80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802827176","https://openalex.org/I4210109259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen T. Wong","raw_affiliation_strings":["Department of Diagnostic Radiology, M.D. Anderson Cancer Center, Houston, TX, USA","Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Medical College of Cornell University, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic Radiology, M.D. Anderson Cancer Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Medical College of Cornell University, Houston, TX, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210109259"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"598","last_page":"601"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.8895242214202881},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7479961514472961},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7242547869682312},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"Glioblastoma","score":0.5816150307655334},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5411450266838074},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4694601595401764},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4504087269306183},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.06182262301445007}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.8895242214202881},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7479961514472961},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7242547869682312},{"id":"https://openalex.org/C2776194525","wikidata":"https://www.wikidata.org/wiki/Q282142","display_name":"Glioblastoma","level":2,"score":0.5816150307655334},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5411450266838074},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4694601595401764},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4504087269306183},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06182262301445007},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2012.6235619","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2012.6235619","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W2002679309","https://openalex.org/W2005814255","https://openalex.org/W2096676285","https://openalex.org/W2098056602","https://openalex.org/W2100835628","https://openalex.org/W2115862526","https://openalex.org/W2117695123","https://openalex.org/W2132358780","https://openalex.org/W2136943418","https://openalex.org/W2161289668","https://openalex.org/W2171890357","https://openalex.org/W2172000360","https://openalex.org/W2419433431","https://openalex.org/W6651135361","https://openalex.org/W6877118713"],"related_works":["https://openalex.org/W1602805286","https://openalex.org/W4225917631","https://openalex.org/W2088686453","https://openalex.org/W2090763504","https://openalex.org/W4200635075","https://openalex.org/W2954466210","https://openalex.org/W2149738946","https://openalex.org/W2326681941","https://openalex.org/W4361251389","https://openalex.org/W2149757685"],"abstract_inverted_index":{"Accurate":[0],"segmentation":[1,68,121],"of":[2,38,66],"Glioblastoma":[3],"multiforme":[4],"(GBM)":[5],"from":[6,69],"MR":[7,71],"images":[8],"is":[9,27,79,111],"important":[10],"for":[11],"sub-typing":[12],"in":[13,18,46],"diagnosis,":[14],"determining":[15],"tumor":[16],"margins":[17],"surgical":[19],"planning,":[20],"and":[21,30,41,102],"selecting":[22],"appropriate":[23],"therapies.":[24],"However,":[25],"it":[26],"a":[28,36,54,74],"challenging":[29],"time-consuming":[31],"task":[32],"because":[33],"GBM":[34,67,130],"has":[35],"variety":[37],"imaging":[39],"characteristics":[40],"often":[42],"deforms":[43],"nearby":[44],"tissues":[45,85],"the":[47,64,83,106,115,125],"brain.":[48],"In":[49],"this":[50],"paper,":[51],"we":[52],"propose":[53],"support":[55],"vector":[56],"machine":[57],"(SVM)":[58],"active":[59,108],"learning":[60,109],"approach":[61,110],"to":[62,81,113],"address":[63],"problem":[65],"multi-modal":[70],"images.":[72],"First,":[73],"knowledge-based":[75],"fuzzy":[76],"clustering":[77],"algorithm":[78,127],"performed":[80],"segment":[82,129],"brain":[84],"into":[86],"six":[87],"classes":[88],"including":[89],"white":[90],"matter":[91,94],"(WM),":[92],"grey":[93],"(GM),":[95],"cerebrospinal":[96],"fluid":[97],"(CSF),":[98],"T2-hyperintense":[99],"regions,":[100],"necrosis":[101],"enhanced":[103],"tumor.":[104],"Then,":[105],"SVM":[107],"applied":[112],"refine":[114],"segmentation.":[116],"Comparative":[117],"studies":[118],"with":[119],"other":[120],"methods":[122],"indicate":[123],"that":[124],"proposed":[126],"can":[128],"more":[131],"accurately.":[132]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}