{"id":"https://openalex.org/W2043027488","doi":"https://doi.org/10.1109/isbi.2012.6235563","title":"Analysis of viral surfing based on fluorescence microscopy imaging and automatic tracking","display_name":"Analysis of viral surfing based on fluorescence microscopy imaging and automatic tracking","publication_year":2012,"publication_date":"2012-05-01","ids":{"openalex":"https://openalex.org/W2043027488","doi":"https://doi.org/10.1109/isbi.2012.6235563","mag":"2043027488"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2012.6235563","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2012.6235563","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065140721","display_name":"Vasil Tsimashchuk","orcid":null},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Vasil Tsimashchuk","raw_affiliation_strings":["BioQuant, IPMB, DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","University of Heidelberg, BioQuant, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioQuant, IPMB, DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]},{"raw_affiliation_string":"University of Heidelberg, BioQuant, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017717870","display_name":"William J. Godinez","orcid":"https://orcid.org/0000-0003-4753-4942"},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"William J. Godinez","raw_affiliation_strings":["BioQuant, IPMB, DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","University of Heidelberg, BioQuant, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioQuant, IPMB, DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]},{"raw_affiliation_string":"University of Heidelberg, BioQuant, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078849410","display_name":"Maik J. Lehmann","orcid":"https://orcid.org/0000-0002-5821-754X"},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Maik Lehmann","raw_affiliation_strings":["Molecular Parasitology, Humboldt University of Berlin, Berlin, Germany","Humboldt-University Berlin, Molecular Parasitology, Philippstrasse 13, 10115 Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Parasitology, Humboldt University of Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]},{"raw_affiliation_string":"Humboldt-University Berlin, Molecular Parasitology, Philippstrasse 13, 10115 Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105166471","display_name":"Karl Rohr","orcid":null},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Karl Rohr","raw_affiliation_strings":["BioQuant, IPMB, DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","University of Heidelberg, BioQuant, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioQuant, IPMB, DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]},{"raw_affiliation_string":"University of Heidelberg, BioQuant, IPMB, and DKFZ Heidelberg, Dept. Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"378","last_page":"381"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11581","display_name":"Viral Infections and Outbreaks Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11581","display_name":"Viral Infections and Outbreaks Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9943000078201294,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/filopodia","display_name":"Filopodia","score":0.815502405166626},{"id":"https://openalex.org/keywords/tracking","display_name":"Tracking (education)","score":0.6986333131790161},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.6967189311981201},{"id":"https://openalex.org/keywords/fluorescence-microscope","display_name":"Fluorescence microscope","score":0.6575025320053101},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5823529958724976},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5183426141738892},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.49020272493362427},{"id":"https://openalex.org/keywords/virus","display_name":"Virus","score":0.4780457615852356},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.4126819968223572},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3988170623779297},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.3207437992095947},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.3021129369735718},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.23683911561965942},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.1984274983406067},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.18891671299934387},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.17126601934432983},{"id":"https://openalex.org/keywords/actin","display_name":"Actin","score":0.15170106291770935},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.15151339769363403}],"concepts":[{"id":"https://openalex.org/C90301020","wikidata":"https://www.wikidata.org/wiki/Q14859810","display_name":"Filopodia","level":3,"score":0.815502405166626},{"id":"https://openalex.org/C2775936607","wikidata":"https://www.wikidata.org/wiki/Q466845","display_name":"Tracking (education)","level":2,"score":0.6986333131790161},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.6967189311981201},{"id":"https://openalex.org/C169274487","wikidata":"https://www.wikidata.org/wiki/Q840211","display_name":"Fluorescence microscope","level":3,"score":0.6575025320053101},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5823529958724976},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5183426141738892},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.49020272493362427},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4780457615852356},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4126819968223572},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3988170623779297},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.3207437992095947},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3021129369735718},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.23683911561965942},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1984274983406067},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18891671299934387},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.17126601934432983},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.15170106291770935},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.15151339769363403},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C19417346","wikidata":"https://www.wikidata.org/wiki/Q7922","display_name":"Pedagogy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2012.6235563","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2012.6235563","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Reduced inequalities","score":0.75,"id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1483307070","https://openalex.org/W1569930776","https://openalex.org/W1964764190","https://openalex.org/W1990064965","https://openalex.org/W2077251032","https://openalex.org/W2101916976","https://openalex.org/W2125636433","https://openalex.org/W2126371427","https://openalex.org/W2129140439","https://openalex.org/W2129534965","https://openalex.org/W2166524747","https://openalex.org/W6679367408"],"related_works":["https://openalex.org/W4211107619","https://openalex.org/W2894139091","https://openalex.org/W2161433272","https://openalex.org/W2315436027","https://openalex.org/W1637909","https://openalex.org/W659245948","https://openalex.org/W2094643072","https://openalex.org/W4206210906","https://openalex.org/W2793462084","https://openalex.org/W2087957833"],"abstract_inverted_index":{"Ordered":[0],"movement":[1],"of":[2,27,31,59,68],"virus":[3,52,60,77],"particles":[4,61],"along":[5],"cell":[6,9,20,69,91],"filopodia":[7,70],"before":[8],"entry":[10],"known":[11],"as":[12,87,89],"viral":[13,28],"surfing":[14,51,76],"is":[15,40,72],"an":[16,45],"important":[17],"pathway":[18],"for":[19,48,66],"infection.":[21],"To":[22],"quantitatively":[23],"analyze":[24],"the":[25],"process":[26],"surfing,":[29],"tracking":[30,49,58],"viruses":[32],"over":[33],"time":[34],"in":[35],"fluorescent":[36],"time-lapse":[37],"microscopy":[38,92],"images":[39,86],"required.":[41],"We":[42],"have":[43],"developed":[44],"automatic":[46],"approach":[47,55,65,80],"single":[50],"particles.":[53,78],"The":[54,79],"combines":[56],"probabilistic":[57],"with":[62],"a":[63],"novel":[64],"segmentation":[67],"which":[71],"used":[73],"to":[74,84],"discriminate":[75],"was":[81],"successfully":[82],"applied":[83],"synthetic":[85],"well":[88],"live":[90],"images.":[93]},"counts_by_year":[{"year":2018,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}