{"id":"https://openalex.org/W2036461653","doi":"https://doi.org/10.1109/isbi.2012.6235505","title":"Feature ranking based nested support vector machine ensemble for medical image classification","display_name":"Feature ranking based nested support vector machine ensemble for medical image classification","publication_year":2012,"publication_date":"2012-05-01","ids":{"openalex":"https://openalex.org/W2036461653","doi":"https://doi.org/10.1109/isbi.2012.6235505","mag":"2036461653","pmid":"https://pubmed.ncbi.nlm.nih.gov/23873289"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2012.6235505","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2012.6235505","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081027256","display_name":"Erdem Varol","orcid":"https://orcid.org/0000-0002-6128-8939"},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Erdem Varol","raw_affiliation_strings":["University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA"],"affiliations":[{"raw_affiliation_string":"University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055050544","display_name":"Bilwaj Gaonkar","orcid":"https://orcid.org/0000-0001-8827-8063"},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bilwaj Gaonkar","raw_affiliation_strings":["Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA","University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA"],"affiliations":[{"raw_affiliation_string":"Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029649151","display_name":"G\u00fcray Erus","orcid":"https://orcid.org/0000-0001-6633-4861"},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guray Erus","raw_affiliation_strings":["Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA","University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA"],"affiliations":[{"raw_affiliation_string":"Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047258772","display_name":"Robert T. Schultz","orcid":"https://orcid.org/0000-0001-9817-3425"},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Schultz","raw_affiliation_strings":["Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA","University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA"],"affiliations":[{"raw_affiliation_string":"Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034999945","display_name":"Christos Davatzikos","orcid":"https://orcid.org/0000-0002-1025-8561"},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christos Davatzikos","raw_affiliation_strings":["Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA","University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA"],"affiliations":[{"raw_affiliation_string":"Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"University of Pennsylvania, Section of Biomedical Image Analysis, Department of Radiology, 3600 Market Street, Philadelphia, PA, 19104, USA","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5081027256"],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":null,"apc_paid":null,"fwci":2.3986,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.87432894,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"146","last_page":"149"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10824","display_name":"Image Retrieval and Classification Techniques","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.8458200693130493},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7787681818008423},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.773503839969635},{"id":"https://openalex.org/keywords/voxel","display_name":"Voxel","score":0.760059118270874},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6505119204521179},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.510580837726593},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.4700067639350891},{"id":"https://openalex.org/keywords/contextual-image-classification","display_name":"Contextual image classification","score":0.45518985390663147},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.4518791735172272},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.2358756959438324}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.8458200693130493},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7787681818008423},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.773503839969635},{"id":"https://openalex.org/C54170458","wikidata":"https://www.wikidata.org/wiki/Q663554","display_name":"Voxel","level":2,"score":0.760059118270874},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6505119204521179},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.510580837726593},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.4700067639350891},{"id":"https://openalex.org/C75294576","wikidata":"https://www.wikidata.org/wiki/Q5165192","display_name":"Contextual image classification","level":3,"score":0.45518985390663147},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.4518791735172272},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.2358756959438324}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi.2012.6235505","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2012.6235505","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},{"id":"pmid:23873289","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23873289","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:europepmc.org:2710790","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3715725","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions","score":0.4300000071525574}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1854064769","https://openalex.org/W1998710995","https://openalex.org/W2071881327","https://openalex.org/W2090425484","https://openalex.org/W2096451472","https://openalex.org/W2115113626","https://openalex.org/W2123225824","https://openalex.org/W2153171432","https://openalex.org/W2155806188","https://openalex.org/W2157848968","https://openalex.org/W2166045895","https://openalex.org/W2167393047","https://openalex.org/W2171831801"],"related_works":["https://openalex.org/W3027020613","https://openalex.org/W2016533837","https://openalex.org/W3167885074","https://openalex.org/W2892386716","https://openalex.org/W4313316311","https://openalex.org/W4306164210","https://openalex.org/W2005234362","https://openalex.org/W2162970382","https://openalex.org/W1997235926","https://openalex.org/W2565656575"],"abstract_inverted_index":{"This":[0],"paper":[1],"presents":[2],"a":[3,29,67,88,102],"method":[4,106],"for":[5,27,109,142],"classification":[6],"of":[7,13,18,81,87,97,138],"structural":[8],"magnetic":[9],"resonance":[10],"images":[11],"(MRI)":[12],"the":[14,44,49,63,98,139],"brain.":[15],"An":[16],"ensemble":[17],"linear":[19],"support":[20],"vector":[21],"machine":[22],"classifiers":[23,100],"(SVMs)":[24],"is":[25,76,91,107],"used":[26],"classifying":[28,110],"subject":[30,90],"as":[31,116,133],"either":[32],"patient":[33],"or":[34],"normal":[35],"control.":[36],"Image":[37],"voxels":[38],"are":[39,59],"first":[40],"ranked":[41],"based":[42,61],"on":[43,62,78,127],"voxel":[45,50,57],"wise":[46],"t-statistics":[47],"between":[48],"intensity":[51],"values":[52],"and":[53,120],"class":[54,85],"labels.":[55],"Then":[56],"subsets":[58],"selected":[60],"rank":[64],"value":[65],"using":[66,101],"forward":[68],"feature":[69],"selection":[70],"scheme.":[71],"Finally,":[72],"an":[73],"SVM":[74,99],"classifier":[75],"trained":[77],"each":[79],"subset":[80],"image":[82,144],"voxels.":[83],"The":[84,105,125],"label":[86],"test":[89],"calculated":[92],"by":[93],"combining":[94],"individual":[95],"decisions":[96],"voting":[103],"mechanism.":[104],"applied":[108],"patients":[111],"with":[112],"neurological":[113],"diseases":[114],"such":[115],"Alzheimer's":[117],"disease":[118],"(AD)":[119],"autism":[121],"spectrum":[122],"disorder":[123],"(ASD).":[124],"results":[126],"both":[128],"datasets":[129],"demonstrate":[130],"superior":[131],"performance":[132],"compared":[134],"to":[135],"two":[136],"state":[137],"art":[140],"methods":[141],"medical":[143],"classification.":[145]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4}],"updated_date":"2026-03-10T16:38:18.471706","created_date":"2025-10-10T00:00:00"}