{"id":"https://openalex.org/W2146358522","doi":"https://doi.org/10.1109/isbi.2011.5872538","title":"Characterization of the default mode functional connectivity in normal aging and Alzheimer's disease: An approach combining entropy-based and graph theoretical measurements","display_name":"Characterization of the default mode functional connectivity in normal aging and Alzheimer's disease: An approach combining entropy-based and graph theoretical measurements","publication_year":2011,"publication_date":"2011-03-01","ids":{"openalex":"https://openalex.org/W2146358522","doi":"https://doi.org/10.1109/isbi.2011.5872538","mag":"2146358522"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2011.5872538","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2011.5872538","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111911275","display_name":"PJ Toussaint","orcid":null},"institutions":[{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"PJ Toussaint","raw_affiliation_strings":["Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]},{"raw_affiliation_string":"Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034301360","display_name":"Sofiane Maiz","orcid":null},"institutions":[{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S Maiz","raw_affiliation_strings":["Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]},{"raw_affiliation_string":"Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050624927","display_name":"David Coynel","orcid":"https://orcid.org/0000-0001-5028-5807"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"D Coynel","raw_affiliation_strings":["Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]},{"raw_affiliation_string":"Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081095787","display_name":"Arnaud Mess\u00e9","orcid":"https://orcid.org/0000-0001-9081-3088"},"institutions":[{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A Messe","raw_affiliation_strings":["Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]},{"raw_affiliation_string":"Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035205639","display_name":"Vincent Perlbarg","orcid":"https://orcid.org/0000-0002-3438-2479"},"institutions":[{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"V Perlbarg","raw_affiliation_strings":["Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]},{"raw_affiliation_string":"Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108650651","display_name":"M.\u2010O. Habert","orcid":null},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"MO Habert","raw_affiliation_strings":["Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]},{"raw_affiliation_string":"Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090830124","display_name":"Habib Benali","orcid":"https://orcid.org/0000-0001-7158-1218"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"H Benali","raw_affiliation_strings":["Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France"],"affiliations":[{"raw_affiliation_string":"Laboratoire dImagerie Fonctionnelle and LINeM, UMR-S 678, INSERM UPMC, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]},{"raw_affiliation_string":"Laboratoire d'Imagerie Fonctionnelle and LINeM, INSERM, UPMC, UMR-S 678 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5111911275"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081"],"apc_list":null,"apc_paid":null,"fwci":0.1374,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.52210155,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"853","last_page":"856"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/precuneus","display_name":"Precuneus","score":0.9497724771499634},{"id":"https://openalex.org/keywords/default-mode-network","display_name":"Default mode network","score":0.900576114654541},{"id":"https://openalex.org/keywords/posterior-cingulate","display_name":"Posterior cingulate","score":0.8420766592025757},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6184226274490356},{"id":"https://openalex.org/keywords/resting-state-fmri","display_name":"Resting state fMRI","score":0.611504316329956},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"Functional connectivity","score":0.48184049129486084},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.4660557210445404},{"id":"https://openalex.org/keywords/clustering-coefficient","display_name":"Clustering coefficient","score":0.4590005874633789},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.33930984139442444},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.3162166476249695},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2500535845756531},{"id":"https://openalex.org/keywords/functional-magnetic-resonance-imaging","display_name":"Functional magnetic resonance imaging","score":0.1647815704345703}],"concepts":[{"id":"https://openalex.org/C2781441883","wikidata":"https://www.wikidata.org/wiki/Q1632835","display_name":"Precuneus","level":3,"score":0.9497724771499634},{"id":"https://openalex.org/C141516989","wikidata":"https://www.wikidata.org/wiki/Q1182555","display_name":"Default mode network","level":3,"score":0.900576114654541},{"id":"https://openalex.org/C2778733324","wikidata":"https://www.wikidata.org/wiki/Q2998088","display_name":"Posterior cingulate","level":3,"score":0.8420766592025757},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6184226274490356},{"id":"https://openalex.org/C66324658","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Resting state fMRI","level":2,"score":0.611504316329956},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.48184049129486084},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4660557210445404},{"id":"https://openalex.org/C22047676","wikidata":"https://www.wikidata.org/wiki/Q898680","display_name":"Clustering coefficient","level":3,"score":0.4590005874633789},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33930984139442444},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.3162166476249695},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2500535845756531},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.1647815704345703}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2011.5872538","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2011.5872538","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1971136065","https://openalex.org/W2015884452","https://openalex.org/W2026384313","https://openalex.org/W2051167879","https://openalex.org/W2054794722","https://openalex.org/W2063859734","https://openalex.org/W2090414491","https://openalex.org/W2106396500","https://openalex.org/W2116649573","https://openalex.org/W2116658855","https://openalex.org/W2118740630","https://openalex.org/W2133703021","https://openalex.org/W2133903921","https://openalex.org/W2137526583","https://openalex.org/W2138991775","https://openalex.org/W2143285014"],"related_works":["https://openalex.org/W2114319021","https://openalex.org/W2074957274","https://openalex.org/W1997326091","https://openalex.org/W2538776211","https://openalex.org/W4281625392","https://openalex.org/W2134858198","https://openalex.org/W1535355457","https://openalex.org/W2390029275","https://openalex.org/W4296798622","https://openalex.org/W2093668364"],"abstract_inverted_index":{"We":[0],"have":[1],"investigated":[2],"functional":[3],"connectivity":[4,46,137],"of":[5,136],"the":[6,43,95,125],"default":[7],"mode":[8],"network":[9],"(DMN)":[10],"in":[11,85,103,116,124],"normal":[12],"aging":[13],"and":[14,27,30,51,76,79,97,139,148],"Alzheimer's":[15],"disease":[16],"(AD)":[17],"using":[18,36,49],"resting":[19,145],"state":[20,146],"fMRI":[21],"at":[22],"3T.":[23],"Images":[24],"from":[25,54],"young":[26,107],"elderly":[28,104,121],"controls,":[29,122],"patients":[31,118],"with":[32],"AD":[33,117],"were":[34,60],"processed":[35],"spatial":[37],"independent":[38],"component":[39],"analysis":[40],"to":[41,106,120,143],"identify":[42],"DMN.":[44],"Functional":[45],"was":[47,82,113],"quantified":[48],"integration":[50,112],"indices":[52],"derived":[53],"graph":[55],"theory.":[56],"Four":[57],"DMN":[58],"sub-systems":[59,99],"identified:":[61],"Frontal":[62,96],"(medial":[63,73],"frontal,":[64],"superior":[65],"frontal),":[66],"Parietal":[67,98],"(precuneus-posterior":[68],"cingulate,":[69],"lateral":[70],"parietal),":[71],"Temporal":[72],"temporal":[74],"cortices),":[75],"Hippocampal":[77],"(left":[78],"right).":[80],"There":[81],"a":[83,133],"decrease":[84],"antero-posterior":[86,111],"interactions":[87,93],"(lower":[88],"global":[89],"efficiency),":[90],"but":[91],"increased":[92],"within":[94],"(higher":[100],"local":[101],"clustering)":[102],"compared":[105,119],"controls.":[108],"The":[109,129],"decreased":[110],"more":[114],"pronounced":[115],"particularly":[123],"precuneus-posterior":[126],"cingulate":[127],"region.":[128],"approach":[130],"allows":[131],"for":[132],"complete":[134],"characterization":[135],"changes":[138],"could":[140],"be":[141],"applied":[142],"other":[144],"networks":[147],"pathologies.":[149]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
