{"id":"https://openalex.org/W2129429995","doi":"https://doi.org/10.1109/isbi.2011.5872422","title":"Integrating structural and diffusion MR information for optic radiation localisation in focal epilepsy patients","display_name":"Integrating structural and diffusion MR information for optic radiation localisation in focal epilepsy patients","publication_year":2011,"publication_date":"2011-03-01","ids":{"openalex":"https://openalex.org/W2129429995","doi":"https://doi.org/10.1109/isbi.2011.5872422","mag":"2129429995"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2011.5872422","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2011.5872422","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011685816","display_name":"Pankaj Daga","orcid":"https://orcid.org/0000-0002-2508-0903"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pankaj Daga","raw_affiliation_strings":["Centre for Medical Image Computing, University College London, London, UK","Centre for Medical Image Computing, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034206577","display_name":"Gavin P. Winston","orcid":"https://orcid.org/0000-0001-9395-1478"},"institutions":[{"id":"https://openalex.org/I3086613782","display_name":"Epilepsy Research UK","ror":"https://ror.org/01gycsq30","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I3086613782"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Gavin Winston","raw_affiliation_strings":["Department of Clinical and Experimental Epilepsy,Institute of Neurology, University College London, London, UK","Department of Clinical and Experimental Epilepsy, UCL, Institute of Neurology, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Epilepsy,Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Clinical and Experimental Epilepsy, UCL, Institute of Neurology, London, UK","institution_ids":["https://openalex.org/I45129253","https://openalex.org/I3086613782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018652821","display_name":"Marc Modat","orcid":"https://orcid.org/0000-0002-5277-8530"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Marc Modat","raw_affiliation_strings":["Centre for Medical Image Computing, University College London, London, UK","Centre for Medical Image Computing, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077080413","display_name":"M. Jorge Cardoso","orcid":"https://orcid.org/0000-0003-1284-2558"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M. Jorge Cardoso","raw_affiliation_strings":["Centre for Medical Image Computing, University College London, London, UK","Centre for Medical Image Computing, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013216468","display_name":"Jason Stretton","orcid":"https://orcid.org/0000-0002-9819-4733"},"institutions":[{"id":"https://openalex.org/I3086613782","display_name":"Epilepsy Research UK","ror":"https://ror.org/01gycsq30","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I3086613782"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jason Stretton","raw_affiliation_strings":["Department of Clinical and Experimental Epilepsy,Institute of Neurology, University College London, London, UK","Department of Clinical and Experimental Epilepsy, UCL, Institute of Neurology, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Epilepsy,Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Clinical and Experimental Epilepsy, UCL, Institute of Neurology, London, UK","institution_ids":["https://openalex.org/I45129253","https://openalex.org/I3086613782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108558508","display_name":"Mark R. Symms","orcid":null},"institutions":[{"id":"https://openalex.org/I3086613782","display_name":"Epilepsy Research UK","ror":"https://ror.org/01gycsq30","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I3086613782"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark Symms","raw_affiliation_strings":["Department of Clinical and Experimental Epilepsy,Institute of Neurology, University College London, London, UK","Department of Clinical and Experimental Epilepsy, UCL, Institute of Neurology, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Epilepsy,Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Clinical and Experimental Epilepsy, UCL, Institute of Neurology, London, UK","institution_ids":["https://openalex.org/I45129253","https://openalex.org/I3086613782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109342021","display_name":"Andrew W. McEvoy","orcid":"https://orcid.org/0000-0002-1078-3761"},"institutions":[{"id":"https://openalex.org/I4210151618","display_name":"National Hospital for Neurology and Neurosurgery","ror":"https://ror.org/048b34d51","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210151618"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew W. McEvoy","raw_affiliation_strings":["National Hospital for Neurology and Neurosurgery, London, UK","National Hospital for Neurology and Neurosurgery London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Hospital for Neurology and Neurosurgery, London, UK","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253"]},{"raw_affiliation_string":"National Hospital for Neurology and Neurosurgery London UK","institution_ids":["https://openalex.org/I4210151618","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113676136","display_name":"David J. Hawkes","orcid":null},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Hawkes","raw_affiliation_strings":["Centre for Medical Image Computing, University College London, London, UK","Centre for Medical Image Computing, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002881267","display_name":"John S. Duncan","orcid":"https://orcid.org/0000-0002-1373-0681"},"institutions":[{"id":"https://openalex.org/I3086613782","display_name":"Epilepsy Research UK","ror":"https://ror.org/01gycsq30","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I3086613782"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John Duncan","raw_affiliation_strings":["Department of Clinical and Experimental Epilepsy,Institute of Neurology, University College London, London, UK","Department of Clinical and Experimental Epilepsy, UCL, Institute of Neurology, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Epilepsy,Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Department of Clinical and Experimental Epilepsy, UCL, Institute of Neurology, London, UK","institution_ids":["https://openalex.org/I45129253","https://openalex.org/I3086613782"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082106258","display_name":"S\u00e9bastien Ourselin","orcid":"https://orcid.org/0000-0002-5694-5340"},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sebastien Ourselin","raw_affiliation_strings":["Centre for Medical Image Computing, University College London, London, UK","Centre for Medical Image Computing, University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Medical Image Computing, University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8055,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.7585114,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"18","issue":null,"first_page":"353","last_page":"356"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mutual-information","display_name":"Mutual information","score":0.5950474739074707},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5750262141227722},{"id":"https://openalex.org/keywords/optic-radiation","display_name":"Optic radiation","score":0.568867027759552},{"id":"https://openalex.org/keywords/fractional-anisotropy","display_name":"Fractional anisotropy","score":0.5641498565673828},{"id":"https://openalex.org/keywords/anisotropic-diffusion","display_name":"Anisotropic diffusion","score":0.5550233125686646},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.5514274835586548},{"id":"https://openalex.org/keywords/imaging-phantom","display_name":"Imaging phantom","score":0.4865516722202301},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4539404511451721},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.4262266755104065},{"id":"https://openalex.org/keywords/medical-physics","display_name":"Medical physics","score":0.36586305499076843},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.3641572594642639},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.36388152837753296},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3149126172065735},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.31137698888778687},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.1859857439994812}],"concepts":[{"id":"https://openalex.org/C152139883","wikidata":"https://www.wikidata.org/wiki/Q252973","display_name":"Mutual information","level":2,"score":0.5950474739074707},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5750262141227722},{"id":"https://openalex.org/C2780317479","wikidata":"https://www.wikidata.org/wiki/Q2511666","display_name":"Optic radiation","level":4,"score":0.568867027759552},{"id":"https://openalex.org/C89916169","wikidata":"https://www.wikidata.org/wiki/Q17014600","display_name":"Fractional anisotropy","level":4,"score":0.5641498565673828},{"id":"https://openalex.org/C203504353","wikidata":"https://www.wikidata.org/wiki/Q4765461","display_name":"Anisotropic diffusion","level":3,"score":0.5550233125686646},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.5514274835586548},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.4865516722202301},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4539404511451721},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.4262266755104065},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.36586305499076843},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.3641572594642639},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.36388152837753296},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3149126172065735},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.31137698888778687},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.1859857439994812}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/isbi.2011.5872422","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2011.5872422","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1322099","is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1322099/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"     In:   (Proceedings) 8th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro. (pp. pp. 353-356).  IEEE (2011)     ","raw_type":"Proceedings paper"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5099999904632568}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1537592854","https://openalex.org/W2021750866","https://openalex.org/W2071881327","https://openalex.org/W2076400752","https://openalex.org/W2107956652","https://openalex.org/W2109060361","https://openalex.org/W2113576511","https://openalex.org/W2157380596","https://openalex.org/W2266635106","https://openalex.org/W2317495993","https://openalex.org/W2323580262","https://openalex.org/W4285719527","https://openalex.org/W6676524165","https://openalex.org/W6693573332","https://openalex.org/W6700678830"],"related_works":["https://openalex.org/W3031573373","https://openalex.org/W2017539237","https://openalex.org/W2607776059","https://openalex.org/W2802561361","https://openalex.org/W2487470953","https://openalex.org/W2415162139","https://openalex.org/W4205593364","https://openalex.org/W2945339633","https://openalex.org/W2080220338","https://openalex.org/W3118966479"],"abstract_inverted_index":{"Current":[0],"state":[1],"of":[2,85,107],"the":[3,10,46,52,100],"art":[4],"neurosurgical":[5],"systems":[6],"do":[7],"not":[8],"exploit":[9],"complementary":[11],"information":[12,49],"provided":[13],"by":[14],"structural":[15,32],"and":[16,22,33,55,69,74,89,96,113],"diffusion":[17],"MRI":[18],"when":[19],"aligning":[20],"pre-operative":[21],"intra-operative":[23],"images.":[24],"We":[25,44],"propose":[26],"a":[27,40,66],"multivariate":[28],"registration":[29],"scheme":[30,54],"where":[31],"fractional":[34],"anisotropy":[35],"data":[36,71],"are":[37],"combined":[38],"in":[39,110],"single":[41],"similarity":[42],"measure.":[43],"formulate":[45],"normalised":[47],"mutual":[48],"expression":[50],"for":[51,83],"multichannel":[53],"compute":[56],"its":[57],"analytical":[58],"derivative.":[59],"The":[60],"method":[61],"was":[62],"validated":[63],"using":[64,72],"both":[65],"numerical":[67],"phantom":[68],"clinical":[70],"pre":[73],"post-operative":[75],"images":[76],"from":[77],"patients":[78],"who":[79],"had":[80],"undergone":[81],"surgery":[82],"treatment":[84],"refractory":[86],"focal":[87],"epilepsy":[88],"shows":[90],"correlation":[91],"between":[92],"visual":[93],"field":[94],"deficit":[95],"predicted":[97],"damage":[98],"to":[99],"optic":[101],"radiation.":[102],"This":[103],"work":[104],"could":[105],"be":[106],"significant":[108],"utility":[109],"image-guided":[111],"interventions":[112],"facilitate":[114],"effective":[115],"surgical":[116],"treatments.":[117]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}