{"id":"https://openalex.org/W2096712622","doi":"https://doi.org/10.1109/isbi.2010.5490404","title":"A new framework for analyzing white matter maturation in early brain development","display_name":"A new framework for analyzing white matter maturation in early brain development","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2096712622","doi":"https://doi.org/10.1109/isbi.2010.5490404","mag":"2096712622","pmid":"https://pubmed.ncbi.nlm.nih.gov/23959442"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2010.5490404","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2010.5490404","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3744242","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071251239","display_name":"Marcel Prastawa","orcid":"https://orcid.org/0000-0002-0278-9637"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marcel Prastawa","raw_affiliation_strings":["Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah 84112","Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, 84112 USA"],"affiliations":[{"raw_affiliation_string":"Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah 84112","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, 84112 USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008608968","display_name":"Neda Sadeghi","orcid":"https://orcid.org/0000-0002-5213-1614"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neda Sadeghi","raw_affiliation_strings":["Scientific Computing and Imaging Institute, University of Utah, Salt Lake, UT, USA","Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, 84112 USA"],"affiliations":[{"raw_affiliation_string":"Scientific Computing and Imaging Institute, University of Utah, Salt Lake, UT, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, 84112 USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052698941","display_name":"John H. Gilmore","orcid":"https://orcid.org/0000-0002-0939-6764"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John H. Gilmore","raw_affiliation_strings":["Department of Psychiatry, North Carolina State University, Chapel Hill, NC, USA","Department of Psychiatry, University of North Carolina, Chapel Hill 27599, USA"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, North Carolina State University, Chapel Hill, NC, USA","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina, Chapel Hill 27599, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006302877","display_name":"Weili Lin","orcid":"https://orcid.org/0000-0002-2900-8204"},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]},{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Weili Lin","raw_affiliation_strings":["Department of Radiology, North Carolina State University, Chapel Hill, NC, USA","Department of Radiology, University of North Carolina, Chapel Hill, 27599, USA"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, North Carolina State University, Chapel Hill, NC, USA","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"Department of Radiology, University of North Carolina, Chapel Hill, 27599, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010769610","display_name":"Guido Gerig","orcid":"https://orcid.org/0000-0002-9547-6233"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guido Gerig","raw_affiliation_strings":["Scientific Computing and Imaging Institute, University of Utah, Salt Lake, UT, USA","Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, 84112 USA"],"affiliations":[{"raw_affiliation_string":"Scientific Computing and Imaging Institute, University of Utah, Salt Lake, UT, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, 84112 USA","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5071251239"],"corresponding_institution_ids":["https://openalex.org/I223532165"],"apc_list":null,"apc_paid":null,"fwci":1.2491,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.80487805,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"97","last_page":"100"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/white-matter","display_name":"White matter","score":0.8416510820388794},{"id":"https://openalex.org/keywords/modalities","display_name":"Modalities","score":0.684374213218689},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.6129748225212097},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5603151321411133},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5350790023803711},{"id":"https://openalex.org/keywords/legendre-polynomials","display_name":"Legendre polynomials","score":0.4563201069831848},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.43962258100509644},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.3359033465385437},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3301534950733185},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.26623114943504333},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.17966067790985107},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.17025092244148254},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.12643495202064514}],"concepts":[{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.8416510820388794},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.684374213218689},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.6129748225212097},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5603151321411133},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5350790023803711},{"id":"https://openalex.org/C111458787","wikidata":"https://www.wikidata.org/wiki/Q215405","display_name":"Legendre polynomials","level":2,"score":0.4563201069831848},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.43962258100509644},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.3359033465385437},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3301534950733185},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.26623114943504333},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.17966067790985107},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17025092244148254},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.12643495202064514},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1109/isbi.2010.5490404","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2010.5490404","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},{"id":"pmid:23959442","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23959442","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.164.5328","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.164.5328","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.sci.utah.edu/~prastawa/papers/ISBI2010_Prastawa_EarlyMaturationMeasures.pdf","raw_type":"text"},{"id":"pmh:oai:europepmc.org:2736125","is_oa":false,"landing_page_url":"http://europepmc.org/articles/PMC3744242","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3744242","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3744242","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"},{"id":"pmh:oai:zenodo.org:1273916","is_oa":true,"landing_page_url":"https://zenodo.org/record/1273916","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferencePaper"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3744242","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3744242","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W796515066","https://openalex.org/W1534664106","https://openalex.org/W2018077021","https://openalex.org/W2028651313","https://openalex.org/W2074976205","https://openalex.org/W2090653043","https://openalex.org/W2091464493","https://openalex.org/W2106716340","https://openalex.org/W2113576511","https://openalex.org/W2120636621","https://openalex.org/W2121014637","https://openalex.org/W4285719527","https://openalex.org/W6678007500"],"related_works":["https://openalex.org/W2736737644","https://openalex.org/W3106446297","https://openalex.org/W2385225694","https://openalex.org/W2185469136","https://openalex.org/W1607269076","https://openalex.org/W2374325362","https://openalex.org/W2024044475","https://openalex.org/W2214763494","https://openalex.org/W1913294887","https://openalex.org/W4296095749"],"abstract_inverted_index":{"The":[0,93],"trajectory":[1],"of":[2,23,32,43,86,91,99,146,157],"early":[3,71],"brain":[4],"development":[5],"is":[6],"marked":[7],"by":[8,12,16],"rapid":[9],"growth":[10,149],"presented":[11],"volume":[13,44],"but":[14],"also":[15],"tissue":[17,55],"property":[18],"changes.":[19],"Capturing":[20],"regional":[21],"characteristics":[22],"axonal":[24],"structuring":[25],"and":[26,45,62,82,88,130],"myelination":[27],"via":[28],"neuroimaging":[29],"requires":[30],"analysis":[31],"longitudinal":[33],"image":[34],"data":[35],"with":[36,117],"multiple":[37],"modalities.":[38],"Complementary":[39],"to":[40,109,153],"earlier":[41],"studies":[42],"cortical":[46],"folding":[47],"analysis,":[48],"this":[49],"paper":[50],"focuses":[51],"on":[52],"white":[53,74,147],"matter":[54,75,148],"changes":[56,101],"as":[57],"seen":[58],"in":[59,73],"multimodal":[60,111],"MRI":[61],"DTI.":[63],"We":[64,133],"propose":[65],"a":[66,78,96,110,154],"new":[67],"framework":[68],"for":[69],"analyzing":[70],"maturation":[72,137],"that":[76,120,135],"generates":[77],"normative":[79],"spatiotemporal":[80],"model":[81,98],"provides":[83],"3D":[84],"maps":[85,138],"absolute":[87],"relative":[89],"indices":[90],"maturation.":[92],"method,":[94],"using":[95,102],"continuous":[97],"intensity":[100],"modified":[103],"Legendre":[104],"polynomials,":[105],"has":[106],"been":[107,122],"applied":[108],"dataset":[112],"(T1W,":[113],"T2W,":[114],"PD,":[115],"DTI)":[116],"8":[118],"subjects":[119],"have":[121],"scanned":[123],"at":[124],"approximately":[125],"2":[126,131],"weeks,":[127],"1":[128],"year,":[129],"years.":[132],"demonstrate":[134],"spatial":[136],"generated":[139],"from":[140],"different":[141,144],"modalities":[142],"capture":[143],"properties":[145],"which":[150],"might":[151],"lead":[152],"better":[155],"understanding":[156],"the":[158],"underlying":[159],"neurobiology.":[160]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}