{"id":"https://openalex.org/W2046624527","doi":"https://doi.org/10.1109/isbi.2010.5490230","title":"A detection-based framework for the analysis of recycling in TIRF microscopy","display_name":"A detection-based framework for the analysis of recycling in TIRF microscopy","publication_year":2010,"publication_date":"2010-04-01","ids":{"openalex":"https://openalex.org/W2046624527","doi":"https://doi.org/10.1109/isbi.2010.5490230","mag":"2046624527"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2010.5490230","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2010.5490230","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023449502","display_name":"Anatole Chessel","orcid":"https://orcid.org/0000-0002-1326-6305"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210161403","display_name":"Biologie cellulaire et Cancer","ror":"https://ror.org/04w11tv37","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210161403","https://openalex.org/I80043"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"A. Chessel","raw_affiliation_strings":["Institut Curie, Cell and Tissue Imaging Facility, IBIS Associates, Inc., Paris, France","Institut Curie, UMR 144 CNRS, Paris, France"],"affiliations":[{"raw_affiliation_string":"Institut Curie, Cell and Tissue Imaging Facility, IBIS Associates, Inc., Paris, France","institution_ids":["https://openalex.org/I80043"]},{"raw_affiliation_string":"Institut Curie, UMR 144 CNRS, Paris, France","institution_ids":["https://openalex.org/I80043","https://openalex.org/I1294671590","https://openalex.org/I4210161403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028388452","display_name":"Bertrand Cinquin","orcid":"https://orcid.org/0000-0002-1702-4354"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I2801148539","display_name":"Synchrotron soleil","ror":"https://ror.org/01ydb3330","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I2801148539","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210161403","display_name":"Biologie cellulaire et Cancer","ror":"https://ror.org/04w11tv37","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210161403","https://openalex.org/I80043"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"B. Cinquin","raw_affiliation_strings":["Institut Curie, UMR 144 CNRS, Paris, France","Soleil Synchrotron, Gif-sur-Yvette, France"],"affiliations":[{"raw_affiliation_string":"Institut Curie, UMR 144 CNRS, Paris, France","institution_ids":["https://openalex.org/I80043","https://openalex.org/I1294671590","https://openalex.org/I4210161403"]},{"raw_affiliation_string":"Soleil Synchrotron, Gif-sur-Yvette, France","institution_ids":["https://openalex.org/I2801148539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088028597","display_name":"Sabine Bardin","orcid":null},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210161403","display_name":"Biologie cellulaire et Cancer","ror":"https://ror.org/04w11tv37","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210161403","https://openalex.org/I80043"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S. Bardin","raw_affiliation_strings":["Institut Curie, UMR 144 CNRS, Paris, France"],"affiliations":[{"raw_affiliation_string":"Institut Curie, UMR 144 CNRS, Paris, France","institution_ids":["https://openalex.org/I80043","https://openalex.org/I1294671590","https://openalex.org/I4210161403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075004436","display_name":"J\u00e9r\u00f4me Boulanger","orcid":"https://orcid.org/0000-0003-0237-3743"},"institutions":[{"id":"https://openalex.org/I4210158379","display_name":"Johann Radon Institute for Computational and Applied Mathematics","ror":"https://ror.org/05a94k872","country_code":"AT","type":"facility","lineage":["https://openalex.org/I138211613","https://openalex.org/I4210158379"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["AT","FR"],"is_corresponding":false,"raw_author_name":"J. Boulanger","raw_affiliation_strings":["Institut Curie, Cell and Tissue Imaging Facility, IBIS Associates, Inc., Paris, France","RICAM, Linz, Austria"],"affiliations":[{"raw_affiliation_string":"Institut Curie, Cell and Tissue Imaging Facility, IBIS Associates, Inc., Paris, France","institution_ids":["https://openalex.org/I80043"]},{"raw_affiliation_string":"RICAM, Linz, Austria","institution_ids":["https://openalex.org/I4210158379"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079455341","display_name":"Jean Salamero","orcid":"https://orcid.org/0000-0002-2610-5826"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210161403","display_name":"Biologie cellulaire et Cancer","ror":"https://ror.org/04w11tv37","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210161403","https://openalex.org/I80043"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J. Salamero","raw_affiliation_strings":["Institut Curie, Cell and Tissue Imaging Facility, IBIS Associates, Inc., Paris, France","Institut Curie, UMR 144 CNRS, Paris, France"],"affiliations":[{"raw_affiliation_string":"Institut Curie, Cell and Tissue Imaging Facility, IBIS Associates, Inc., Paris, France","institution_ids":["https://openalex.org/I80043"]},{"raw_affiliation_string":"Institut Curie, UMR 144 CNRS, Paris, France","institution_ids":["https://openalex.org/I80043","https://openalex.org/I1294671590","https://openalex.org/I4210161403"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033807512","display_name":"Charles Kervrann","orcid":"https://orcid.org/0000-0001-6263-0452"},"institutions":[{"id":"https://openalex.org/I1326498283","display_name":"Institut national de recherche en sciences et technologies du num\u00e9rique","ror":"https://ror.org/02kvxyf05","country_code":"FR","type":"government","lineage":["https://openalex.org/I1326498283"]},{"id":"https://openalex.org/I4210133778","display_name":"Centre Inria de l'Universit\u00e9 de Rennes","ror":"https://ror.org/04040yw90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1326498283","https://openalex.org/I4210133778"]},{"id":"https://openalex.org/I4210159481","display_name":"Math\u00e9matiques et Informatique Appliqu\u00e9es du G\u00e9nome \u00e0 l'Environnement","ror":"https://ror.org/05qdnns64","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210088668","https://openalex.org/I4210159481"]},{"id":"https://openalex.org/I4387153087","display_name":"Math\u00e9matiques et Informatique Appliqu\u00e9es","ror":"https://ror.org/00780az30","country_code":null,"type":"facility","lineage":["https://openalex.org/I22248866","https://openalex.org/I277688954","https://openalex.org/I277688954","https://openalex.org/I4210088668","https://openalex.org/I4387153087"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. Kervrann","raw_affiliation_strings":["INRA, UR341 Math\u00e9matiques et Informatique Appliqu\u00e9es, Jouy-en-Josas, France","INRIA Centre Rennes-Bretagne Atlantique, Rennes, France"],"affiliations":[{"raw_affiliation_string":"INRA, UR341 Math\u00e9matiques et Informatique Appliqu\u00e9es, Jouy-en-Josas, France","institution_ids":["https://openalex.org/I4210159481","https://openalex.org/I4387153087"]},{"raw_affiliation_string":"INRIA Centre Rennes-Bretagne Atlantique, Rennes, France","institution_ids":["https://openalex.org/I4210133778","https://openalex.org/I1326498283"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5023449502"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210161403","https://openalex.org/I80043"],"apc_list":null,"apc_paid":null,"fwci":0.3869,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.77897294,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"1","issue":null,"first_page":"1281","last_page":"1284"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9950000047683716,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/total-internal-reflection-fluorescence-microscope","display_name":"Total internal reflection fluorescence microscope","score":0.8466286063194275},{"id":"https://openalex.org/keywords/endocytosis","display_name":"Endocytosis","score":0.8176635503768921},{"id":"https://openalex.org/keywords/exocytosis","display_name":"Exocytosis","score":0.7753271460533142},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.5734995007514954},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.439728319644928},{"id":"https://openalex.org/keywords/membrane","display_name":"Membrane","score":0.4039227366447449},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3929067552089691},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.364146888256073},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.35976317524909973},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.3301102817058563},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.23316383361816406},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.22934049367904663},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.22264552116394043},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.15698900818824768},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.07752731442451477}],"concepts":[{"id":"https://openalex.org/C121381206","wikidata":"https://www.wikidata.org/wiki/Q902514","display_name":"Total internal reflection fluorescence microscope","level":3,"score":0.8466286063194275},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.8176635503768921},{"id":"https://openalex.org/C175969161","wikidata":"https://www.wikidata.org/wiki/Q323426","display_name":"Exocytosis","level":3,"score":0.7753271460533142},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.5734995007514954},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.439728319644928},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.4039227366447449},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3929067552089691},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.364146888256073},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35976317524909973},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3301102817058563},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23316383361816406},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.22934049367904663},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.22264552116394043},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.15698900818824768},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07752731442451477}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi.2010.5490230","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2010.5490230","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.212.5700","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.212.5700","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.irisa.fr/vista/Papers/2010_isbi_chessel.pdf","raw_type":"text"},{"id":"pmh:oai:HAL:inria-00541102v1","is_oa":false,"landing_page_url":"https://inria.hal.science/inria-00541102","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5490230&tag=1","raw_type":"Conference papers"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W125261686","https://openalex.org/W1508514374","https://openalex.org/W2001532503","https://openalex.org/W2016966047","https://openalex.org/W2029794613","https://openalex.org/W2046133662","https://openalex.org/W2110596359","https://openalex.org/W2110998393","https://openalex.org/W2121749936","https://openalex.org/W2123120886","https://openalex.org/W2160225986","https://openalex.org/W2609703245","https://openalex.org/W2913455019","https://openalex.org/W6630541305","https://openalex.org/W6736680782"],"related_works":["https://openalex.org/W2034791541","https://openalex.org/W2607082573","https://openalex.org/W2041890090","https://openalex.org/W2028888912","https://openalex.org/W1949005472","https://openalex.org/W3216596429","https://openalex.org/W2058833411","https://openalex.org/W2413150078","https://openalex.org/W2013262011","https://openalex.org/W2072572820"],"abstract_inverted_index":{"Endocytosis/recycling":[0],"and":[1,77],"exocytosis":[2],"are":[3],"mechanisms":[4],"conserved":[5],"through":[6],"evolution":[7],"allowing":[8],"cells":[9],"to":[10,18],"communicate":[11],"with":[12,45,72],"their":[13],"external":[14],"medium.":[15],"In":[16],"order":[17],"study":[19],"these":[20],"dynamic":[21],"processes,":[22],"the":[23,37,46,80],"present":[24],"work":[25],"proposes":[26],"a":[27,66],"patch-based":[28],"method":[29],"for":[30],"detecting":[31],"recycling":[32,83],"or":[33],"exocytotic":[34],"events":[35],"at":[36],"Plasma":[38],"membrane":[39,82],"in":[40],"fast":[41],"TIRF":[42,58],"microscopy":[43],"combined":[44],"computation":[47],"of":[48,52,79],"normalized":[49],"temporal":[50],"representations":[51],"those":[53],"events.":[54],"Evaluation,":[55],"performed":[56],"on":[57],"sequences":[59],"showing":[60],"Transferrin":[61],"receptor":[62],"(TfR)":[63],"recycling,":[64],"validates":[65],"high":[67],"detection":[68],"rate":[69],"fully":[70],"compatible":[71],"an":[73],"automatic":[74],"data":[75],"extraction":[76],"analysis":[78],"plasma":[81],"process.":[84]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-04-15T08:11:43.952461","created_date":"2025-10-10T00:00:00"}