{"id":"https://openalex.org/W2163369027","doi":"https://doi.org/10.1109/isbi.2008.4541201","title":"Geometric alignment of 2D gel electrophoresis images using physics-based elastic registration","display_name":"Geometric alignment of 2D gel electrophoresis images using physics-based elastic registration","publication_year":2008,"publication_date":"2008-05-01","ids":{"openalex":"https://openalex.org/W2163369027","doi":"https://doi.org/10.1109/isbi.2008.4541201","mag":"2163369027"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2008.4541201","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2008.4541201","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038055772","display_name":"Stefan W\u00f6rz","orcid":null},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Worz","raw_affiliation_strings":["BIOQUANT, IPMB, and DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BIOQUANT, IPMB, and DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089009957","display_name":"Marie\u2010Luise Winz","orcid":"https://orcid.org/0000-0003-0740-8618"},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marie-Luise Winz","raw_affiliation_strings":["BIOQUANT, IPMB, and DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BIOQUANT, IPMB, and DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105166471","display_name":"Karl Rohr","orcid":null},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Karl Rohr","raw_affiliation_strings":["BIOQUANT, IPMB, and DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BIOQUANT, IPMB, and DKFZ Heidelberg, Department Bioinformatics and Functional Genomics, Biomedical Computer Vision Group, University of Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I223822909"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"1","issue":null,"first_page":"1135","last_page":"1138"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9854999780654907,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9811000227928162,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/image-registration","display_name":"Image registration","score":0.7682104110717773},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.5525210499763489},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.48971322178840637},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.47193118929862976},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4703300893306732}],"concepts":[{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.7682104110717773},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.5525210499763489},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.48971322178840637},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.47193118929862976},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4703300893306732}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2008.4541201","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2008.4541201","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1606374853","https://openalex.org/W1996999814","https://openalex.org/W2005226747","https://openalex.org/W2038753515","https://openalex.org/W2050776270","https://openalex.org/W2053943081","https://openalex.org/W2060372462","https://openalex.org/W2066505297","https://openalex.org/W2075934392","https://openalex.org/W2086277380","https://openalex.org/W2120967246","https://openalex.org/W2131938193","https://openalex.org/W2147507661","https://openalex.org/W2147555557"],"related_works":["https://openalex.org/W2058170566","https://openalex.org/W2755342338","https://openalex.org/W2772917594","https://openalex.org/W2166024367","https://openalex.org/W3116076068","https://openalex.org/W2229312674","https://openalex.org/W2951359407","https://openalex.org/W2079911747","https://openalex.org/W1969923398","https://openalex.org/W2775347418"],"abstract_inverted_index":{"A":[0],"key":[1],"technique":[2],"for":[3,24,51],"protein":[4],"analysis":[5],"is":[6,28,49],"the":[7,35,52,80],"geometric":[8],"alignment":[9],"of":[10,34,54,68,71,79],"2D":[11],"gel":[12,66],"electrophoresis":[13],"(2-DE)":[14],"images.":[15,56],"We":[16,57,82],"introduce":[17],"a":[18,76,87,90],"new":[19],"hybrid":[20,92],"elastic":[21,43,93],"registration":[22,53,94],"approach":[23,40,62],"2-DE":[25,55,65],"images,":[26],"which":[27,48],"based":[29],"on":[30],"an":[31],"analytic":[32],"solution":[33],"Navier":[36],"equation.":[37],"With":[38],"this":[39],"cross-effects":[41],"in":[42],"deformations":[44],"can":[45],"be":[46],"handled,":[47],"important":[50],"have":[58,74,83],"successfully":[59],"applied":[60],"our":[61],"to":[63],"register":[64],"images":[67],"different":[69],"levels":[70],"complexity":[72],"and":[73],"performed":[75],"quantitative":[77],"evaluation":[78],"results.":[81],"also":[84],"carried":[85],"out":[86],"comparison":[88],"with":[89],"previous":[91],"scheme.":[95]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}