{"id":"https://openalex.org/W2136519362","doi":"https://doi.org/10.1109/isbi.2008.4541087","title":"Tomosynthesis-based radioactive seed localization in prostate brachytherapy using modified distance map images","display_name":"Tomosynthesis-based radioactive seed localization in prostate brachytherapy using modified distance map images","publication_year":2008,"publication_date":"2008-05-01","ids":{"openalex":"https://openalex.org/W2136519362","doi":"https://doi.org/10.1109/isbi.2008.4541087","mag":"2136519362","pmid":"https://pubmed.ncbi.nlm.nih.gov/20066153"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2008.4541087","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2008.4541087","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100626269","display_name":"Junghoon Lee","orcid":"https://orcid.org/0000-0001-7633-2915"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Junghoon Lee","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, USA","Department of Electrical and Computer Engineering, Johns Hopkins University, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Johns Hopkins University, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100359288","display_name":"Xiaofeng Liu","orcid":"https://orcid.org/0000-0002-4514-2016"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaofeng Liu","raw_affiliation_strings":["Computer Science, Johns Hopkins University, Baltimore, MD, USA"],"affiliations":[{"raw_affiliation_string":"Computer Science, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103559032","display_name":"Ameet Jain","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ameet K. Jain","raw_affiliation_strings":["Computer Science, Baltimore, MD, U.S.A"],"affiliations":[{"raw_affiliation_string":"Computer Science, Baltimore, MD, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066682675","display_name":"Jerry L. Prince","orcid":"https://orcid.org/0000-0002-6553-0876"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerry L. Prince","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Johns Hopkins University, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Johns Hopkins University, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084753910","display_name":"G\u00e1bor Fichtinger","orcid":"https://orcid.org/0000-0002-6354-262X"},"institutions":[{"id":"https://openalex.org/I204722609","display_name":"Queen's University","ror":"https://ror.org/02y72wh86","country_code":"CA","type":"education","lineage":["https://openalex.org/I204722609"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Gabor Fichtinger","raw_affiliation_strings":["Computer Science, Johns Hopkins University, Baltimore, MD, USA","School of Computing, Queen's University, Canada"],"affiliations":[{"raw_affiliation_string":"Computer Science, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"School of Computing, Queen's University, Canada","institution_ids":["https://openalex.org/I204722609"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100626269"],"corresponding_institution_ids":["https://openalex.org/I145311948"],"apc_list":null,"apc_paid":null,"fwci":1.1803,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.80994043,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"32","issue":null,"first_page":"680","last_page":"683"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10481","display_name":"Computer Graphics and Visualization Techniques","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1704","display_name":"Computer Graphics and Computer-Aided Design"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brachytherapy","display_name":"Brachytherapy","score":0.758998692035675},{"id":"https://openalex.org/keywords/imaging-phantom","display_name":"Imaging phantom","score":0.7566894292831421},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.6946676969528198},{"id":"https://openalex.org/keywords/projection","display_name":"Projection (relational algebra)","score":0.6877268552780151},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.676097571849823},{"id":"https://openalex.org/keywords/tomosynthesis","display_name":"Tomosynthesis","score":0.5931122303009033},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5758975744247437},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5585729479789734},{"id":"https://openalex.org/keywords/prostate-brachytherapy","display_name":"Prostate brachytherapy","score":0.5480197072029114},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.5148721933364868},{"id":"https://openalex.org/keywords/matching","display_name":"Matching (statistics)","score":0.47389379143714905},{"id":"https://openalex.org/keywords/volume","display_name":"Volume (thermodynamics)","score":0.4115500748157501},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.35193878412246704},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.32962435483932495},{"id":"https://openalex.org/keywords/mammography","display_name":"Mammography","score":0.19272789359092712},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.148977130651474},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.14682722091674805},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.1217174232006073},{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.1151157021522522},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.11007285118103027},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.06734049320220947}],"concepts":[{"id":"https://openalex.org/C2777416452","wikidata":"https://www.wikidata.org/wiki/Q896687","display_name":"Brachytherapy","level":3,"score":0.758998692035675},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.7566894292831421},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.6946676969528198},{"id":"https://openalex.org/C57493831","wikidata":"https://www.wikidata.org/wiki/Q3134666","display_name":"Projection (relational algebra)","level":2,"score":0.6877268552780151},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.676097571849823},{"id":"https://openalex.org/C147454874","wikidata":"https://www.wikidata.org/wiki/Q7820316","display_name":"Tomosynthesis","level":5,"score":0.5931122303009033},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5758975744247437},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5585729479789734},{"id":"https://openalex.org/C2778648096","wikidata":"https://www.wikidata.org/wiki/Q17009878","display_name":"Prostate brachytherapy","level":4,"score":0.5480197072029114},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.5148721933364868},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.47389379143714905},{"id":"https://openalex.org/C20556612","wikidata":"https://www.wikidata.org/wiki/Q4469374","display_name":"Volume (thermodynamics)","level":2,"score":0.4115500748157501},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.35193878412246704},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.32962435483932495},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.19272789359092712},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.148977130651474},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.14682722091674805},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1217174232006073},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.1151157021522522},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.11007285118103027},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.06734049320220947},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1109/isbi.2008.4541087","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2008.4541087","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},{"id":"pmid:20066153","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20066153","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.717.1224","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.717.1224","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://iacl.ece.jhu.edu//proceedings/iacl/2008/LeexISBI08-Tomosynthesis-based_radioactive_seed_localization.pdf","raw_type":"text"},{"id":"pmh:oai:europepmc.org:1948174","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2802341","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1544347682","https://openalex.org/W1965734230","https://openalex.org/W1994501138","https://openalex.org/W1996192718","https://openalex.org/W2006971554","https://openalex.org/W2012809219","https://openalex.org/W2023660080","https://openalex.org/W2042660694","https://openalex.org/W2056401399","https://openalex.org/W2077697891","https://openalex.org/W2110937068","https://openalex.org/W2134375305","https://openalex.org/W2152502257","https://openalex.org/W2167740652"],"related_works":["https://openalex.org/W1968581313","https://openalex.org/W2810663015","https://openalex.org/W2102373670","https://openalex.org/W2809967836","https://openalex.org/W2807466365","https://openalex.org/W2133110153","https://openalex.org/W4256435254","https://openalex.org/W2408551504","https://openalex.org/W94890742","https://openalex.org/W1992267514"],"abstract_inverted_index":{"We":[0],"have":[1],"developed":[2],"a":[3,41,53,107],"tomosynthesis-based":[4],"radioactive":[5],"seed":[6,59,87],"localization":[7],"method":[8,21],"for":[9],"prostate":[10],"brachytherapy.":[11],"In":[12],"contrast":[13],"to":[14,51],"the":[15,64,85,99,104],"projection":[16,46],"image-based":[17],"matching":[18],"approach,":[19],"our":[20],"does":[22],"not":[23],"involve":[24],"explicit":[25],"segmentation":[26],"of":[27,44,56,101,106],"seeds":[28,70,102],"and":[29,48,67,117],"can":[30,89],"recover":[31],"hidden":[32],"seeds.":[33],"Modified":[34],"distance":[35],"map":[36],"images":[37,96],"are":[38,49,61,71],"computed":[39],"from":[40,63,92],"limited":[42],"number":[43,100],"x-ray":[45],"images,":[47],"backprojected":[50],"reconstuct":[52],"3-D":[54],"volume":[55,66],"interest.":[57],"Candidate":[58],"locations":[60,88],"extracted":[62],"reconstructed":[65],"false":[68],"positive":[69],"eliminated":[72],"by":[73],"solving":[74],"an":[75],"optimal":[76],"geometry":[77],"coverage":[78],"problem.":[79],"The":[80,111],"simulation":[81],"results":[82],"indicate":[83],"that":[84],"implanted":[86],"be":[90],"estimated":[91],"three":[93],"or":[94],"four":[95],"depending":[97],"on":[98],"if":[103],"pose":[105],"C-arm":[108],"is":[109],"known.":[110],"algorithm":[112],"was":[113],"validated":[114],"using":[115],"phantom":[116],"clinical":[118],"patient":[119],"data.":[120]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}