{"id":"https://openalex.org/W2107779001","doi":"https://doi.org/10.1109/isbi.2008.4540932","title":"A novel learning based segmentation method for rodent brain structures using MRI","display_name":"A novel learning based segmentation method for rodent brain structures using MRI","publication_year":2008,"publication_date":"2008-05-01","ids":{"openalex":"https://openalex.org/W2107779001","doi":"https://doi.org/10.1109/isbi.2008.4540932","mag":"2107779001"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2008.4540932","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2008.4540932","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026395073","display_name":"Jinghao Zhou","orcid":"https://orcid.org/0000-0002-7744-0405"},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jinghao Zhou","raw_affiliation_strings":["CBIM, Rutgers, State University of New Jersey, Piscataway, NJ, USA"],"affiliations":[{"raw_affiliation_string":"CBIM, Rutgers, State University of New Jersey, Piscataway, NJ, USA","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113944166","display_name":"Sukmoon Chang","orcid":null},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sukmoon Chang","raw_affiliation_strings":["CBIM, Rutgers, State University of New Jersey, Piscataway, NJ, USA","Computer Science, Capital College, Pennslyvania State University, Middletown, PA, USA"],"affiliations":[{"raw_affiliation_string":"CBIM, Rutgers, State University of New Jersey, Piscataway, NJ, USA","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Computer Science, Capital College, Pennslyvania State University, Middletown, PA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100404959","display_name":"Qingshan Liu","orcid":"https://orcid.org/0000-0002-5512-6984"},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qingshan Liu","raw_affiliation_strings":["CBIM, Rutgers, State University of New Jersey, Piscataway, NJ, USA"],"affiliations":[{"raw_affiliation_string":"CBIM, Rutgers, State University of New Jersey, Piscataway, NJ, USA","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008386954","display_name":"George D. Pappas","orcid":"https://orcid.org/0000-0003-1762-4963"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George Pappas","raw_affiliation_strings":["Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA"],"affiliations":[{"raw_affiliation_string":"Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098329451","display_name":"Vasilios Boronikolas","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vasilios Boronikolas","raw_affiliation_strings":["Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA"],"affiliations":[{"raw_affiliation_string":"Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086522965","display_name":"Michael Michaelides","orcid":"https://orcid.org/0000-0003-0398-4917"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Michaelides","raw_affiliation_strings":["Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA"],"affiliations":[{"raw_affiliation_string":"Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002969658","display_name":"Nora D. Volkow","orcid":"https://orcid.org/0000-0001-6668-0908"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nora D. Volkow","raw_affiliation_strings":["Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA"],"affiliations":[{"raw_affiliation_string":"Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112101927","display_name":"Panayotis K. Thanos","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Panayotis K. Thanos","raw_affiliation_strings":["Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA"],"affiliations":[{"raw_affiliation_string":"Behavior Neuropharmacology and Neuroimaging Lab, Medical Department, Brockhaven National Laboratory, Upton, NY, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064437234","display_name":"Dimitris Metaxas","orcid":"https://orcid.org/0000-0001-7142-7640"},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dimitris Metaxas","raw_affiliation_strings":["CBIM, Rutgers, State University of New Jersey, Piscataway, NJ, USA"],"affiliations":[{"raw_affiliation_string":"CBIM, Rutgers, State University of New Jersey, Piscataway, NJ, USA","institution_ids":["https://openalex.org/I102322142"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5026395073"],"corresponding_institution_ids":["https://openalex.org/I102322142"],"apc_list":null,"apc_paid":null,"fwci":1.0535,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.79721908,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"61","last_page":"64"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10824","display_name":"Image Retrieval and Classification Techniques","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10627","display_name":"Advanced Image and Video Retrieval Techniques","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7558354139328003},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6448882222175598},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6361418962478638},{"id":"https://openalex.org/keywords/initialization","display_name":"Initialization","score":0.5787123441696167},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5299331545829773},{"id":"https://openalex.org/keywords/active-shape-model","display_name":"Active shape model","score":0.4872209131717682},{"id":"https://openalex.org/keywords/internal-capsule","display_name":"Internal capsule","score":0.468711793422699},{"id":"https://openalex.org/keywords/ground-truth","display_name":"Ground truth","score":0.4660806357860565},{"id":"https://openalex.org/keywords/corpus-callosum","display_name":"Corpus callosum","score":0.44833970069885254},{"id":"https://openalex.org/keywords/neocortex","display_name":"Neocortex","score":0.44125914573669434},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.4118937849998474},{"id":"https://openalex.org/keywords/s\u00f8rensen\u2013dice-coefficient","display_name":"S\u00f8rensen\u2013Dice coefficient","score":0.4113411009311676},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.39587998390197754},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.38351911306381226},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.38281381130218506},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1578681766986847},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1522892713546753},{"id":"https://openalex.org/keywords/white-matter","display_name":"White matter","score":0.07144883275032043}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7558354139328003},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6448882222175598},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6361418962478638},{"id":"https://openalex.org/C114466953","wikidata":"https://www.wikidata.org/wiki/Q6034165","display_name":"Initialization","level":2,"score":0.5787123441696167},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5299331545829773},{"id":"https://openalex.org/C129641003","wikidata":"https://www.wikidata.org/wiki/Q267189","display_name":"Active shape model","level":3,"score":0.4872209131717682},{"id":"https://openalex.org/C2777796809","wikidata":"https://www.wikidata.org/wiki/Q604747","display_name":"Internal capsule","level":4,"score":0.468711793422699},{"id":"https://openalex.org/C146849305","wikidata":"https://www.wikidata.org/wiki/Q370766","display_name":"Ground truth","level":2,"score":0.4660806357860565},{"id":"https://openalex.org/C2778183499","wikidata":"https://www.wikidata.org/wiki/Q223851","display_name":"Corpus callosum","level":2,"score":0.44833970069885254},{"id":"https://openalex.org/C2777222312","wikidata":"https://www.wikidata.org/wiki/Q726562","display_name":"Neocortex","level":2,"score":0.44125914573669434},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.4118937849998474},{"id":"https://openalex.org/C163892561","wikidata":"https://www.wikidata.org/wiki/Q2613728","display_name":"S\u00f8rensen\u2013Dice coefficient","level":4,"score":0.4113411009311676},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.39587998390197754},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.38351911306381226},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.38281381130218506},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1578681766986847},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1522892713546753},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.07144883275032043},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2008.4540932","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2008.4540932","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1513013675","https://openalex.org/W1522048223","https://openalex.org/W1553407966","https://openalex.org/W1995796138","https://openalex.org/W2027955893","https://openalex.org/W2038952578","https://openalex.org/W2101524669","https://openalex.org/W2116087808","https://openalex.org/W2122632052","https://openalex.org/W2137346077","https://openalex.org/W2145622106","https://openalex.org/W2147646630","https://openalex.org/W2163815564","https://openalex.org/W2167338900","https://openalex.org/W2215365459","https://openalex.org/W2616101183","https://openalex.org/W4230946174"],"related_works":["https://openalex.org/W4310571718","https://openalex.org/W2382512470","https://openalex.org/W2114740332","https://openalex.org/W3130546594","https://openalex.org/W3029648274","https://openalex.org/W4200158463","https://openalex.org/W2805741438","https://openalex.org/W1989270739","https://openalex.org/W2054553044","https://openalex.org/W2535946666"],"abstract_inverted_index":{"This":[0,29],"paper":[1],"reports":[2],"a":[3],"novel":[4],"method":[5,44,84],"for":[6,45],"fully":[7],"automated":[8],"segmentation":[9,47,100],"of":[10,48,81,102],"rodent":[11,49,110],"brain":[12,50,111],"volume":[13],"by":[14],"extending":[15],"the":[16,66,90,97,103],"robust":[17,67,104],"active":[18,68,105],"shape":[19,26,32,42,69,106],"models":[20],"to":[21,89],"incorporate":[22],"an":[23,40],"automatic":[24,30,41],"prior":[25,31],"selection":[27,33],"process.":[28],"process":[34],"using":[35],"support":[36],"vector":[37],"machines":[38],"provides":[39],"initialization":[43],"further":[46],"structures":[51],"such":[52],"as":[53],"Cerebellum,":[54],"Neocortex,":[55],"Corpus":[56],"Callosum,":[57],"External":[58],"Capsule,":[59],"Caudate":[60],"Putamen,":[61],"Hippocampus":[62],"and":[63],"Ventricles":[64],"with":[65],"model":[70,107],"framework":[71,108],"in":[72,109],"magnetic":[73],"resonance":[74],"images":[75],"(MRI).":[76],"The":[77],"mean":[78],"successful":[79],"rate":[80],"this":[82],"classification":[83],"shows":[85],"92.2%":[86],"accuracy":[87],"compared":[88],"expert-defined":[91],"ground":[92],"truth.":[93],"We":[94],"also":[95],"demonstrate":[96],"very":[98],"promising":[99],"results":[101],"volume.":[112]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}