{"id":"https://openalex.org/W2133419089","doi":"https://doi.org/10.1109/isbi.2006.1624941","title":"Lateral Asymmetry in the Shape of Brain Ventricles in Control and Schizophrenia Groups","display_name":"Lateral Asymmetry in the Shape of Brain Ventricles in Control and Schizophrenia Groups","publication_year":2006,"publication_date":"2006-05-25","ids":{"openalex":"https://openalex.org/W2133419089","doi":"https://doi.org/10.1109/isbi.2006.1624941","mag":"2133419089"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2006.1624941","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2006.1624941","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"3rd IEEE International Symposium on Biomedical Imaging: Macro to Nano, 2006.","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080105817","display_name":"J Graham","orcid":null},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"J. Graham","raw_affiliation_strings":["University of Manchester, Institute of Science and Technology, UK","Manchester Univ.#TAB#"],"affiliations":[{"raw_affiliation_string":"University of Manchester, Institute of Science and Technology, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Manchester Univ.#TAB#","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033286621","display_name":"Kola Babalola","orcid":"https://orcid.org/0000-0003-1384-8433"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K.O. Babalola","raw_affiliation_strings":["University of Manchester, Institute of Science and Technology, UK","Manchester Univ.#TAB#"],"affiliations":[{"raw_affiliation_string":"University of Manchester, Institute of Science and Technology, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Manchester Univ.#TAB#","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033183852","display_name":"William G. Honer","orcid":"https://orcid.org/0000-0002-7628-5108"},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"W.G. Honer","raw_affiliation_strings":["University of British Columbia, Canada","University of British Columbia, Canada ,"],"affiliations":[{"raw_affiliation_string":"University of British Columbia, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"University of British Columbia, Canada ,","institution_ids":["https://openalex.org/I141945490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054968193","display_name":"Donna J. Lang","orcid":"https://orcid.org/0000-0001-9373-1555"},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"D. Lang","raw_affiliation_strings":["University of British Columbia, Canada","University of British Columbia, Canada ,"],"affiliations":[{"raw_affiliation_string":"University of British Columbia, Canada","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"University of British Columbia, Canada ,","institution_ids":["https://openalex.org/I141945490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046854632","display_name":"Lili C. Kopala","orcid":null},"institutions":[{"id":"https://openalex.org/I129902397","display_name":"Dalhousie University","ror":"https://ror.org/01e6qks80","country_code":"CA","type":"education","lineage":["https://openalex.org/I129902397"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"L. Kopala","raw_affiliation_strings":["Dalhousie University, Canada","Dalhousie University (Canada )"],"affiliations":[{"raw_affiliation_string":"Dalhousie University, Canada","institution_ids":["https://openalex.org/I129902397"]},{"raw_affiliation_string":"Dalhousie University (Canada )","institution_ids":["https://openalex.org/I129902397"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032130924","display_name":"Robert Vandorpe","orcid":null},"institutions":[{"id":"https://openalex.org/I129902397","display_name":"Dalhousie University","ror":"https://ror.org/01e6qks80","country_code":"CA","type":"education","lineage":["https://openalex.org/I129902397"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"R. Vandorpe","raw_affiliation_strings":["Dalhousie University, Canada","Dalhousie University (Canada )"],"affiliations":[{"raw_affiliation_string":"Dalhousie University, Canada","institution_ids":["https://openalex.org/I129902397"]},{"raw_affiliation_string":"Dalhousie University (Canada )","institution_ids":["https://openalex.org/I129902397"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5080105817"],"corresponding_institution_ids":["https://openalex.org/I28407311"],"apc_list":null,"apc_paid":null,"fwci":0.417,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.62331986,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"414","last_page":"417"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12417","display_name":"Morphological variations and asymmetry","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2608","display_name":"Geometry and Topology"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12417","display_name":"Morphological variations and asymmetry","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2608","display_name":"Geometry and Topology"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11830","display_name":"Point processes and geometric inequalities","score":0.9847999811172485,"subfield":{"id":"https://openalex.org/subfields/2604","display_name":"Applied Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10421","display_name":"Pleistocene-Era Hominins and Archaeology","score":0.934499979019165,"subfield":{"id":"https://openalex.org/subfields/3314","display_name":"Anthropology"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asymmetry","display_name":"Asymmetry","score":0.8069076538085938},{"id":"https://openalex.org/keywords/ventricle","display_name":"Ventricle","score":0.7000648379325867},{"id":"https://openalex.org/keywords/lateral-ventricles","display_name":"Lateral ventricles","score":0.6063134074211121},{"id":"https://openalex.org/keywords/projection","display_name":"Projection (relational algebra)","score":0.5075089335441589},{"id":"https://openalex.org/keywords/brain-asymmetry","display_name":"Brain asymmetry","score":0.46652278304100037},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.41567695140838623},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"Linear discriminant analysis","score":0.41512298583984375},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.3938676118850708},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2762187719345093},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.2704322338104248},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.23889389634132385},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2073608934879303},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.14219385385513306},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.11536207795143127},{"id":"https://openalex.org/keywords/lateralization-of-brain-function","display_name":"Lateralization of brain function","score":0.10637983679771423},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.09411025047302246},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.08180102705955505}],"concepts":[{"id":"https://openalex.org/C38976095","wikidata":"https://www.wikidata.org/wiki/Q752641","display_name":"Asymmetry","level":2,"score":0.8069076538085938},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.7000648379325867},{"id":"https://openalex.org/C2780744974","wikidata":"https://www.wikidata.org/wiki/Q1929623","display_name":"Lateral ventricles","level":2,"score":0.6063134074211121},{"id":"https://openalex.org/C57493831","wikidata":"https://www.wikidata.org/wiki/Q3134666","display_name":"Projection (relational algebra)","level":2,"score":0.5075089335441589},{"id":"https://openalex.org/C195650424","wikidata":"https://www.wikidata.org/wiki/Q4955813","display_name":"Brain asymmetry","level":3,"score":0.46652278304100037},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.41567695140838623},{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.41512298583984375},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3938676118850708},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2762187719345093},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2704322338104248},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.23889389634132385},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2073608934879303},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14219385385513306},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.11536207795143127},{"id":"https://openalex.org/C79840881","wikidata":"https://www.wikidata.org/wiki/Q1080497","display_name":"Lateralization of brain function","level":2,"score":0.10637983679771423},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.09411025047302246},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.08180102705955505},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/isbi.2006.1624941","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2006.1624941","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"3rd IEEE International Symposium on Biomedical Imaging: Macro to Nano, 2006.","raw_type":"proceedings-article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/bd706181-a6c2-42b8-b972-052305dc82f2","is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/bd706181-a6c2-42b8-b972-052305dc82f2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Graham, J, Babalola, K O, Honer, W G, Lang, D, Kopala, L & Vandorpe, R 2006, Lateral asymmetry in the shape of brain ventricles in control and schizophrenia groups. in 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings|IEEE Int. Symp. Biomed. Imag. Nano Macro Proc.. vol. 2006, IEEE, pp. 414-417, 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Arlington, VA, 1/07/06. https://doi.org/10.1109/ISBI.2006.1624941","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pure.atira.dk:publications/bd706181-a6c2-42b8-b972-052305dc82f2","is_oa":false,"landing_page_url":"https://www.research.manchester.ac.uk/portal/en/publications/lateral-asymmetry-in-the-shape-of-brain-ventricles-in-control-and-schizophrenia-groups(bd706181-a6c2-42b8-b972-052305dc82f2).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Reduced inequalities","score":0.6899999976158142,"id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W13877688","https://openalex.org/W1850915977","https://openalex.org/W1970157989","https://openalex.org/W2000533601","https://openalex.org/W2038952578","https://openalex.org/W2042243471","https://openalex.org/W2071881327","https://openalex.org/W2083645773","https://openalex.org/W2086342835","https://openalex.org/W2157908245","https://openalex.org/W2398887630","https://openalex.org/W4230349253"],"related_works":["https://openalex.org/W1980563100","https://openalex.org/W1644661642","https://openalex.org/W4297670902","https://openalex.org/W3031331673","https://openalex.org/W2035154026","https://openalex.org/W2065779551","https://openalex.org/W2050217822","https://openalex.org/W3102935140","https://openalex.org/W4298144021","https://openalex.org/W2155826194"],"abstract_inverted_index":{"We":[0,83],"use":[1],"point":[2],"distribution":[3],"models":[4],"(PDMs)":[5],"to":[6],"investigate":[7],"lateral":[8],"asymmetries":[9],"in":[10,50,63,87,93,105,121],"the":[11,38,48,56,64,69,76,88,91,106],"shape":[12,51],"of":[13,58,68,75,90,108,119],"brain":[14],"ventricles":[15,62],"between":[16],"control":[17,97],"subjects":[18],"and":[19,31,60,96,111,117],"people":[20],"with":[21],"schizophrenia.":[22],"Ventricle":[23],"surfaces":[24],"were":[25],"extracted":[26],"from":[27],"T2-weighted":[28],"MR":[29],"images":[30],"PDMs":[32],"generated":[33],"using":[34],"structural":[35],"correspondences":[36],"on":[37],"individual":[39,77],"surfaces.":[40],"Using":[41],"paired":[42],"linear":[43],"discriminant":[44],"analysis":[45],"we":[46],"calculate":[47],"vector":[49],"space":[52],"that":[53],"maximally":[54],"separates":[55],"shapes":[57,79],"right":[59],"left":[61],"group.":[65],"The":[66],"magnitude":[67,89],"asymmetry":[70,92],"is":[71,100],"quantified":[72],"by":[73],"projection":[74],"ventricle":[78],"onto":[80],"this":[81],"vector.":[82],"observe":[84],"significant":[85],"differences":[86],"both":[94,122],"schizophrenia":[95],"groups.":[98],"There":[99],"also":[101],"a":[102],"clear":[103],"difference":[104],"pattern":[107],"asymmetry.":[109],"Male":[110],"female":[112],"subgroups":[113],"show":[114],"different":[115],"magnitudes":[116],"patterns":[118],"asymmetry,":[120],"groups":[123]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}