{"id":"https://openalex.org/W2137676251","doi":"https://doi.org/10.1109/isbi.2004.1398770","title":"Cell-based screening for function","display_name":"Cell-based screening for function","publication_year":2005,"publication_date":"2005-04-06","ids":{"openalex":"https://openalex.org/W2137676251","doi":"https://doi.org/10.1109/isbi.2004.1398770","mag":"2137676251"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2004.1398770","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2004.1398770","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 04EX821)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004165808","display_name":"Tal Shay","orcid":"https://orcid.org/0000-0003-0755-1350"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"T. Shay","raw_affiliation_strings":["Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067902117","display_name":"Suha Naffar-Abu-Amara","orcid":null},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"S. Naffar-Abu-Amara","raw_affiliation_strings":["Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023183032","display_name":"Yael Paran","orcid":"https://orcid.org/0000-0001-9544-6213"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Y. Paran","raw_affiliation_strings":["Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001623411","display_name":"Eli Zamir","orcid":"https://orcid.org/0000-0001-8226-5480"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"E. Zamir","raw_affiliation_strings":["Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037692256","display_name":"Yuvalal Liron","orcid":"https://orcid.org/0000-0003-1509-1147"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Y. Liron","raw_affiliation_strings":["Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046264807","display_name":"Benjamin Geiger","orcid":"https://orcid.org/0000-0001-8559-6373"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"B. Geiger","raw_affiliation_strings":["Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055525128","display_name":"Zvi Kam","orcid":"https://orcid.org/0000-0003-1306-7178"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Z. Kam","raw_affiliation_strings":["Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I53964585"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":null,"first_page":"1243","last_page":"1246"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9812999963760376,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.697157084941864},{"id":"https://openalex.org/keywords/throughput","display_name":"Throughput","score":0.6292381286621094},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.48976898193359375},{"id":"https://openalex.org/keywords/image-processing","display_name":"Image processing","score":0.4845985174179077},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.45429790019989014},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.45344027876853943},{"id":"https://openalex.org/keywords/cell-function","display_name":"Cell function","score":0.4522186517715454},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.4289621114730835},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.38113588094711304},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.3456292152404785},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.29810410737991333},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.1262415647506714},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.11133632063865662},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.10899755358695984},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.06640064716339111}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.697157084941864},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.6292381286621094},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.48976898193359375},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.4845985174179077},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.45429790019989014},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.45344027876853943},{"id":"https://openalex.org/C2994604686","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell function","level":3,"score":0.4522186517715454},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.4289621114730835},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.38113588094711304},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3456292152404785},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.29810410737991333},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.1262415647506714},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.11133632063865662},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10899755358695984},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06640064716339111},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2004.1398770","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2004.1398770","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 04EX821)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1988683816","https://openalex.org/W2018952748","https://openalex.org/W2076927398","https://openalex.org/W2142111204"],"related_works":["https://openalex.org/W2136583354","https://openalex.org/W2111238207","https://openalex.org/W2760721665","https://openalex.org/W2112044895","https://openalex.org/W330130819","https://openalex.org/W2288610023","https://openalex.org/W3121416282","https://openalex.org/W2281389338","https://openalex.org/W64511347","https://openalex.org/W4200428755"],"abstract_inverted_index":{"Biological":[0],"image":[1],"analysis":[2,19,31,42],"software":[3],"packages":[4],"offer":[5],"tools":[6,16],"to":[7,52],"analyze":[8],"microscope":[9],"images":[10,45,69],"of":[11,14,32,35,43,61],"cells.":[12],"Some":[13],"these":[15],"allow":[17],"quantitative":[18],"through":[20],"interactive":[21],"processing.":[22],"High-throughput":[23],"applications":[24],"employing":[25],"microscopy":[26],"for":[27,54],"cell-based":[28],"assays":[29],"require":[30],"large":[33],"number":[34],"images.":[36],"We":[37],"describe":[38],"here":[39],"acquisition":[40],"and":[41,58,70],"cell":[44,68,72],"in":[46,56,71],"high":[47,66],"throughput":[48],"automated":[49],"mode":[50],"aiming":[51],"screen":[53],"effects":[55],"structure":[57],"molecular":[59],"organization":[60],"cellular":[62],"components":[63],"recorded":[64],"by":[65],"resolution":[67],"motility.":[73]},"counts_by_year":[],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}