{"id":"https://openalex.org/W2150330984","doi":"https://doi.org/10.1109/isbi.2004.1398623","title":"Automatic quantification of microtubule dynamics","display_name":"Automatic quantification of microtubule dynamics","publication_year":2005,"publication_date":"2005-04-12","ids":{"openalex":"https://openalex.org/W2150330984","doi":"https://doi.org/10.1109/isbi.2004.1398623","mag":"2150330984"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2004.1398623","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2004.1398623","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 04EX821)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012436496","display_name":"Stathis Hadjidemetriou","orcid":"https://orcid.org/0000-0002-3205-5511"},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Hadjidemetriou","raw_affiliation_strings":["Department of Electrical Engineering and Diagnostic Radiology, Department of Cell Biology, Department of Pathology-Pathology Informatics, Yale University, New Heaven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Diagnostic Radiology, Department of Cell Biology, Department of Pathology-Pathology Informatics, Yale University, New Heaven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046673670","display_name":"James S. Duncan","orcid":"https://orcid.org/0000-0002-5167-9856"},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.S. Duncan","raw_affiliation_strings":["Department of Electrical Engineering and Diagnostic Radiology, Department of Cell Biology, Department of Pathology-Pathology Informatics, Yale University, New Heaven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Diagnostic Radiology, Department of Cell Biology, Department of Pathology-Pathology Informatics, Yale University, New Heaven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059006111","display_name":"Derek Toomre","orcid":"https://orcid.org/0000-0002-6827-8127"},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Toomre","raw_affiliation_strings":["Department of Electrical Engineering and Diagnostic Radiology, Department of Cell Biology, Department of Pathology-Pathology Informatics, Yale University, New Heaven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Diagnostic Radiology, Department of Cell Biology, Department of Pathology-Pathology Informatics, Yale University, New Heaven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016816358","display_name":"David Tuck","orcid":"https://orcid.org/0000-0001-7313-5158"},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Tuck","raw_affiliation_strings":["Department of Electrical Engineering and Diagnostic Radiology, Department of Cell Biology, Department of Pathology-Pathology Informatics, Yale University, New Heaven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Diagnostic Radiology, Department of Cell Biology, Department of Pathology-Pathology Informatics, Yale University, New Heaven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":21.4324,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.99453125,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"2","issue":null,"first_page":"656","last_page":"659"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9837999939918518,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microtubule","display_name":"Microtubule","score":0.7360485196113586},{"id":"https://openalex.org/keywords/limiting","display_name":"Limiting","score":0.722070574760437},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.7058927416801453},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.545981764793396},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.543325662612915},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.5074958205223083},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.39834725856781006},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3722919225692749},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.26901963353157043},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1484290361404419},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.11172929406166077},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.09843119978904724},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.07892626523971558}],"concepts":[{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.7360485196113586},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.722070574760437},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.7058927416801453},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.545981764793396},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.543325662612915},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5074958205223083},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.39834725856781006},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3722919225692749},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.26901963353157043},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1484290361404419},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11172929406166077},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.09843119978904724},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.07892626523971558},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/isbi.2004.1398623","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2004.1398623","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 04EX821)","raw_type":"proceedings-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.584.1132","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.584.1132","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://noodle.med.yale.edu/~stathis/Publications/hadjidemetriou_isbi_2004.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4399999976158142,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1528558170","https://openalex.org/W1580200468","https://openalex.org/W1585348905","https://openalex.org/W2025691233","https://openalex.org/W2026275287","https://openalex.org/W2041158925","https://openalex.org/W2091798758","https://openalex.org/W2114336941","https://openalex.org/W2119444142","https://openalex.org/W2130785652","https://openalex.org/W2138787629","https://openalex.org/W2159617609","https://openalex.org/W2615765930","https://openalex.org/W3003662786","https://openalex.org/W4250747843","https://openalex.org/W6635023584"],"related_works":["https://openalex.org/W2900684760","https://openalex.org/W2114542479","https://openalex.org/W2054976643","https://openalex.org/W2073057352","https://openalex.org/W2473195300","https://openalex.org/W2064422190","https://openalex.org/W4210494266","https://openalex.org/W2750958300","https://openalex.org/W2057381363","https://openalex.org/W2071528423"],"abstract_inverted_index":{"The":[0,50],"dynamics":[1,29,48],"of":[2,17,62],"the":[3,18,46,60,63],"microtubule":[4,28,47],"assembly":[5,19],"are":[6,30],"very":[7],"significant":[8],"both":[9],"for":[10],"cell":[11],"function":[12,16],"and":[13,25,38,55],"structure.":[14],"Abnormal":[15],"is":[20,35],"involved":[21],"in":[22],"neurodegenerative":[23],"diseases":[24],"cancer.":[26],"Currently,":[27],"typically":[31],"analyzed":[32],"manually,":[33],"which":[34],"time":[36],"consuming":[37],"limiting.":[39],"We":[40,58],"present":[41],"an":[42],"algorithm":[43,64],"that":[44],"quantifies":[45],"automatically.":[49],"quantification":[51],"becomes":[52],"simpler,":[53],"easier,":[54],"more":[56],"extensive.":[57],"examine":[59],"sensitivity":[61],"using":[65],"phantom":[66],"as":[67,69],"well":[68],"real":[70],"data.":[71]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}