{"id":"https://openalex.org/W1836681583","doi":"https://doi.org/10.1109/isbi.2002.1029375","title":"Automated interictal spike detection and source localization in MEG using ICA and spatial-temporal clustering","display_name":"Automated interictal spike detection and source localization in MEG using ICA and spatial-temporal clustering","publication_year":2003,"publication_date":"2003-06-25","ids":{"openalex":"https://openalex.org/W1836681583","doi":"https://doi.org/10.1109/isbi.2002.1029375","mag":"1836681583"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2002.1029375","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2002.1029375","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings IEEE International Symposium on Biomedical Imaging","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040437691","display_name":"Alexei Ossadtchi","orcid":"https://orcid.org/0000-0001-8827-9429"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"A. Ossadtchi","raw_affiliation_strings":["SIPI, University of Southern California, Los Angeles, CA, USA"],"affiliations":[{"raw_affiliation_string":"SIPI, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054387045","display_name":"Richard M. Leahy","orcid":"https://orcid.org/0000-0002-7278-5471"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.M. Leahy","raw_affiliation_strings":["SIPI, University of Southern California, Los Angeles, CA, USA"],"affiliations":[{"raw_affiliation_string":"SIPI, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041475859","display_name":"John C. Mosher","orcid":"https://orcid.org/0000-0002-3221-229X"},"institutions":[{"id":"https://openalex.org/I1343871089","display_name":"Los Alamos National Laboratory","ror":"https://ror.org/01e41cf67","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I1343871089","https://openalex.org/I198811213","https://openalex.org/I4210120050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.C. Mosher","raw_affiliation_strings":["Los Alamos National Laboratory, Los Alamos, NM, USA"],"affiliations":[{"raw_affiliation_string":"Los Alamos National Laboratory, Los Alamos, NM, USA","institution_ids":["https://openalex.org/I1343871089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045447995","display_name":"Nancy L\u00f3pez","orcid":null},"institutions":[{"id":"https://openalex.org/I1306117286","display_name":"Huntington Hospital","ror":"https://ror.org/02e271b61","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1306117286"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N. Lopez","raw_affiliation_strings":["Epilepsy and Brain Mapping Program, Huntington Hospital, Pasadena, CA, USA"],"affiliations":[{"raw_affiliation_string":"Epilepsy and Brain Mapping Program, Huntington Hospital, Pasadena, CA, USA","institution_ids":["https://openalex.org/I1306117286"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076518409","display_name":"William W. Sutherling","orcid":null},"institutions":[{"id":"https://openalex.org/I1306117286","display_name":"Huntington Hospital","ror":"https://ror.org/02e271b61","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1306117286"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Sutherling","raw_affiliation_strings":["Epilepsy and Brain Mapping Program, Huntington Hospital, Pasadena, CA, USA"],"affiliations":[{"raw_affiliation_string":"Epilepsy and Brain Mapping Program, Huntington Hospital, Pasadena, CA, USA","institution_ids":["https://openalex.org/I1306117286"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5040437691"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":null,"apc_paid":null,"fwci":0.2928,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.53609831,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"7","issue":null,"first_page":"785","last_page":"788"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11447","display_name":"Blind Source Separation Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11447","display_name":"Blind Source Separation Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12946","display_name":"Fractal and DNA sequence analysis","score":0.9902999997138977,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ictal","display_name":"Ictal","score":0.8344823718070984},{"id":"https://openalex.org/keywords/independent-component-analysis","display_name":"Independent component analysis","score":0.7722909450531006},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6713516712188721},{"id":"https://openalex.org/keywords/magnetoencephalography","display_name":"Magnetoencephalography","score":0.6585972309112549},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6447905898094177},{"id":"https://openalex.org/keywords/focus","display_name":"Focus (optics)","score":0.6318379044532776},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.6043619513511658},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.561124861240387},{"id":"https://openalex.org/keywords/spike","display_name":"Spike (software development)","score":0.5172199010848999},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.5156811475753784},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1727372407913208},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.12395426630973816}],"concepts":[{"id":"https://openalex.org/C17755696","wikidata":"https://www.wikidata.org/wiki/Q16564780","display_name":"Ictal","level":3,"score":0.8344823718070984},{"id":"https://openalex.org/C51432778","wikidata":"https://www.wikidata.org/wiki/Q1259145","display_name":"Independent component analysis","level":2,"score":0.7722909450531006},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6713516712188721},{"id":"https://openalex.org/C556910895","wikidata":"https://www.wikidata.org/wiki/Q384188","display_name":"Magnetoencephalography","level":3,"score":0.6585972309112549},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6447905898094177},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.6318379044532776},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.6043619513511658},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.561124861240387},{"id":"https://openalex.org/C2781390188","wikidata":"https://www.wikidata.org/wiki/Q25203449","display_name":"Spike (software development)","level":2,"score":0.5172199010848999},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.5156811475753784},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1727372407913208},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12395426630973816},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2002.1029375","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2002.1029375","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings IEEE International Symposium on Biomedical Imaging","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.49000000953674316}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1533423434","https://openalex.org/W1549057490","https://openalex.org/W1563527684","https://openalex.org/W1970789124","https://openalex.org/W1971266900","https://openalex.org/W1978298662","https://openalex.org/W1990381576","https://openalex.org/W2002515985","https://openalex.org/W2009914532","https://openalex.org/W2018283014","https://openalex.org/W2019502123","https://openalex.org/W2020592127","https://openalex.org/W2035950812","https://openalex.org/W2048124453","https://openalex.org/W2048588522","https://openalex.org/W2057095720","https://openalex.org/W2068341702","https://openalex.org/W2096636692","https://openalex.org/W2108384452","https://openalex.org/W2126767504","https://openalex.org/W2130947713","https://openalex.org/W2135503775","https://openalex.org/W2159835457","https://openalex.org/W2616531566","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2622163794","https://openalex.org/W3153433522","https://openalex.org/W2063347383","https://openalex.org/W2515491719","https://openalex.org/W4220833343","https://openalex.org/W2466901773","https://openalex.org/W1605351496","https://openalex.org/W1413446224","https://openalex.org/W2090312564","https://openalex.org/W2405240590"],"abstract_inverted_index":{"MEG":[0,102],"dipole":[1],"localization":[2,56,74],"of":[3,15,27,40,47,59,78,136,150,169,176,193],"epileptic":[4],"spikes":[5,115],"is":[6],"useful":[7],"in":[8],"epilepsy":[9],"surgery":[10],"for":[11],"mapping":[12],"the":[13,48,60,82,100,124,134,151,184,190],"extent":[14],"abnormal":[16],"cortex":[17],"and":[18,31,50,104,132,140,164,188],"to":[19,75,98,182],"focus":[20],"intracranial":[21],"electrodes.":[22],"Visually":[23],"analyzing":[24],"large":[25],"amounts":[26],"data":[28,49,103],"produces":[29],"fatigue":[30],"error.":[32],"Most":[33],"existing":[34],"methods":[35],"are":[36,126,180,189],"based":[37,153],"on":[38,154],"matching":[39],"interictal":[41,86],"spike":[42,87],"templates":[43],"or":[44],"predictive":[45],"filtering":[46],"do":[51],"not":[52],"explicitly":[53],"include":[54],"source":[55,73],"as":[57],"part":[58],"analysis.":[61],"We":[62,89],"describe":[63],"a":[64,148,174],"fully":[65],"automated":[66],"method":[67,97],"that":[68,84,108,157],"combines":[69],"time-series":[70],"analysis":[71],"with":[72,128,173],"detect":[76],"clusters":[77,168],"focal":[79,129],"generators":[80],"within":[81],"brain":[83],"produce":[85],"activity.":[88],"first":[90],"use":[91],"an":[92],"ICA":[93],"(Independent":[94],"Component":[95],"Analysis)":[96],"decompose":[99],"multichannel":[101],"identify":[105],"those":[106,119],"components":[107],"exhibit":[109],"spikelike":[110],"characteristics.":[111],"From":[112],"these":[113],"detected":[114],"we":[116,146],"then":[117],"find":[118],"whose":[120],"spatial":[121],"topographies":[122],"across":[123],"array":[125],"consistent":[127],"neural":[130],"sources":[131,152,187],"determine":[133],"foci":[135],"equivalent":[137,170],"current":[138,171],"dipoles":[139,172],"their":[141,162],"associated":[142],"time":[143,165],"courses.":[144,166],"Finally":[145],"perform":[147],"clustering":[149],"distance":[155],"metrics":[156],"takes":[158],"into":[159],"consideration":[160],"both":[161],"locations":[163],"Tight":[167],"fit":[175],"greater":[177],"than":[178],"95%":[179],"considered":[181],"be":[183],"reliably":[185],"determined":[186],"final":[191],"output":[192],"our":[194],"detection":[195],"scheme.":[196]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}