{"id":"https://openalex.org/W2157062797","doi":"https://doi.org/10.1109/isbi.2002.1029297","title":"Detecting dynamic and genetic effects on brain structure using high-dimensional cortical pattern matching","display_name":"Detecting dynamic and genetic effects on brain structure using high-dimensional cortical pattern matching","publication_year":2003,"publication_date":"2003-06-25","ids":{"openalex":"https://openalex.org/W2157062797","doi":"https://doi.org/10.1109/isbi.2002.1029297","mag":"2157062797","pmid":"https://pubmed.ncbi.nlm.nih.gov/19759832"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2002.1029297","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2002.1029297","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings IEEE International Symposium on Biomedical Imaging","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2744079","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100606557","display_name":"Paul M. Thompson","orcid":"https://orcid.org/0000-0002-4720-8867"},"institutions":[{"id":"https://openalex.org/I2799798094","display_name":"UCLA Health","ror":"https://ror.org/01d88se56","country_code":"US","type":"funder","lineage":["https://openalex.org/I2799798094"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"P.M. Thompson","raw_affiliation_strings":["Laboratory of Neuro Imaging, UCLA School of Medicine, Los Angeles","Laboratory of Neuro Imaging,School of Medicine, University of California, Los Angeles, Los Angeles, USA"],"affiliations":[{"raw_affiliation_string":"Laboratory of Neuro Imaging, UCLA School of Medicine, Los Angeles","institution_ids":["https://openalex.org/I2799798094","https://openalex.org/I161318765"]},{"raw_affiliation_string":"Laboratory of Neuro Imaging,School of Medicine, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077894974","display_name":"K\u00f4ji Hayashi","orcid":"https://orcid.org/0000-0003-3446-0913"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K.M. Hayashi","raw_affiliation_strings":["Laboratory of Neuro Imaging,School of Medicine, University of California, Los Angeles, Los Angeles, USA"],"affiliations":[{"raw_affiliation_string":"Laboratory of Neuro Imaging,School of Medicine, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036061196","display_name":"Greig I. de Zubicaray","orcid":"https://orcid.org/0000-0003-4506-0579"},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"G. de Zubicaray","raw_affiliation_strings":["Centre for Magnetic Resonance, University of Queensland, Australia"],"affiliations":[{"raw_affiliation_string":"Centre for Magnetic Resonance, University of Queensland, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050750564","display_name":"Andrew L. Janke","orcid":"https://orcid.org/0000-0003-0547-5171"},"institutions":[{"id":"https://openalex.org/I1292859797","display_name":"Montreal Neurological Institute and Hospital","ror":"https://ror.org/05ghs6f64","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1292859797"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]},{"id":"https://openalex.org/I165143802","display_name":"University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU","CA"],"is_corresponding":false,"raw_author_name":"A.L. Janke","raw_affiliation_strings":["Centre for Magnetic Resonance, University of Queensland, Australia","McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Canada"],"affiliations":[{"raw_affiliation_string":"Centre for Magnetic Resonance, University of Queensland, Australia","institution_ids":["https://openalex.org/I165143802"]},{"raw_affiliation_string":"McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Canada","institution_ids":["https://openalex.org/I1292859797","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034274387","display_name":"Stephen Rose","orcid":"https://orcid.org/0000-0003-1558-6297"},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"S.E. Rose","raw_affiliation_strings":["Centre for Magnetic Resonance, University of Queensland, Australia"],"affiliations":[{"raw_affiliation_string":"Centre for Magnetic Resonance, University of Queensland, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012499417","display_name":"James Semple","orcid":null},"institutions":[{"id":"https://openalex.org/I188950975","display_name":"GlaxoSmithKline (United Kingdom)","ror":"https://ror.org/01xsqw823","country_code":"GB","type":"company","lineage":["https://openalex.org/I188950975"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Semple","raw_affiliation_strings":["GlaxoSmithKline Pharmaceuticals Public Limited Company, Cambridge, UK"],"affiliations":[{"raw_affiliation_string":"GlaxoSmithKline Pharmaceuticals Public Limited Company, Cambridge, UK","institution_ids":["https://openalex.org/I188950975"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113554218","display_name":"David M. Doddrell","orcid":null},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"D.M. Doddrell","raw_affiliation_strings":["Centre for Magnetic, University of Queensland, Australia"],"affiliations":[{"raw_affiliation_string":"Centre for Magnetic, University of Queensland, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090423513","display_name":"Tyrone D. Cannon","orcid":"https://orcid.org/0000-0002-5632-3154"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T.D. Cannon","raw_affiliation_strings":["Laboratory of Neuro Imaging,School of Medicine, University of California, Los Angeles, Los Angeles, USA"],"affiliations":[{"raw_affiliation_string":"Laboratory of Neuro Imaging,School of Medicine, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014949118","display_name":"Arthur W. Toga","orcid":"https://orcid.org/0000-0001-7902-3755"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.W. Toga","raw_affiliation_strings":["Laboratory of Neuro Imaging,School of Medicine, University of California, Los Angeles, Los Angeles, USA"],"affiliations":[{"raw_affiliation_string":"Laboratory of Neuro Imaging,School of Medicine, University of California, Los Angeles, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5100606557"],"corresponding_institution_ids":["https://openalex.org/I161318765","https://openalex.org/I2799798094"],"apc_list":null,"apc_paid":null,"fwci":3.0471,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.91625325,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"2002","issue":null,"first_page":"473","last_page":"476"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12417","display_name":"Morphological variations and asymmetry","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2608","display_name":"Geometry and Topology"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12417","display_name":"Morphological variations and asymmetry","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2608","display_name":"Geometry and Topology"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9891999959945679,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9621999859809875,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covariant-transformation","display_name":"Covariant transformation","score":0.5728508830070496},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5659911036491394},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5356056094169617},{"id":"https://openalex.org/keywords/brain-morphometry","display_name":"Brain morphometry","score":0.5234346389770508},{"id":"https://openalex.org/keywords/human-brain","display_name":"Human brain","score":0.5007448196411133},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4733588397502899},{"id":"https://openalex.org/keywords/matching","display_name":"Matching (statistics)","score":0.4572365880012512},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.412390798330307},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.23203763365745544},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2207116186618805},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.16534698009490967},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1379929482936859},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.1245618462562561}],"concepts":[{"id":"https://openalex.org/C9136319","wikidata":"https://www.wikidata.org/wiki/Q362640","display_name":"Covariant transformation","level":2,"score":0.5728508830070496},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5659911036491394},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5356056094169617},{"id":"https://openalex.org/C145940234","wikidata":"https://www.wikidata.org/wiki/Q4955830","display_name":"Brain morphometry","level":3,"score":0.5234346389770508},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.5007448196411133},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4733588397502899},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.4572365880012512},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.412390798330307},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23203763365745544},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2207116186618805},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.16534698009490967},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1379929482936859},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1245618462562561},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1109/isbi.2002.1029297","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2002.1029297","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings IEEE International Symposium on Biomedical Imaging","raw_type":"proceedings-article"},{"id":"pmid:19759832","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19759832","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE International Symposium on Biomedical Imaging","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.65.6109","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.65.6109","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.loni.ucla.edu/~thompson/ISBI2002/ISBI2002_v4_draft.pdf","raw_type":"text"},{"id":"pmh:oai:espace.library.uq.edu.au:UQ:345086","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402388","display_name":"Queensland's institutional digital repository (The University of Queensland)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I165143802","host_organization_name":"The University of Queensland","host_organization_lineage":["https://openalex.org/I165143802"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Conference Paper"},{"id":"pmh:oai:europepmc.org:1527111","is_oa":false,"landing_page_url":"http://europepmc.org/articles/PMC2744079","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2744079","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2744079","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2744079","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2744079","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc IEEE Int Symp Biomed Imaging","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W154947979","https://openalex.org/W1553609571","https://openalex.org/W1571835489","https://openalex.org/W1602679020","https://openalex.org/W1983607598","https://openalex.org/W2006557707","https://openalex.org/W2041398617","https://openalex.org/W2062648684","https://openalex.org/W2109875016","https://openalex.org/W2110437310","https://openalex.org/W2115245436","https://openalex.org/W2143736779","https://openalex.org/W2143895814","https://openalex.org/W2151685314","https://openalex.org/W2167393047","https://openalex.org/W2168866216","https://openalex.org/W2171251197","https://openalex.org/W7030062261"],"related_works":["https://openalex.org/W304910524","https://openalex.org/W2025009645","https://openalex.org/W2167840431","https://openalex.org/W2062513055","https://openalex.org/W2033580864","https://openalex.org/W2089217176","https://openalex.org/W2067069213","https://openalex.org/W2034362312","https://openalex.org/W4313421958","https://openalex.org/W2766678282"],"abstract_inverted_index":{"We":[0,43,111,140],"briefly":[1],"describe":[2],"a":[3,53,104],"set":[4],"of":[5,12,34,70,94,122],"algorithms":[6],"to":[7,66,87,103,148,161],"detect":[8],"and":[9,14,32,100,132],"visualize":[10],"effects":[11,36],"disease":[13,130],"genetic":[15,135],"factors":[16],"on":[17,37,59,137,156,165],"the":[18,30],"brain.":[19],"Extreme":[20],"variations":[21],"in":[22,40,47,72,115,126,145,168],"cortical":[23,54,90,149],"anatomy,":[24],"even":[25],"among":[26],"normal":[27],"subjects,":[28],"complicate":[29],"detection":[31],"mapping":[33,119,134],"systematic":[35],"brain":[38,75,138,166],"structure":[39,167],"human":[41,169],"populations.":[42,170],"tackle":[44],"this":[45],"problem":[46],"two":[48,116],"stages.":[49],"First,":[50],"we":[51,152],"develop":[52],"pattern":[55],"matching":[56],"approach,":[57],"based":[58,155],"metrically":[60],"covariant":[61],"partial":[62],"differential":[63],"equations":[64],"(PDEs),":[65],"associate":[67],"corresponding":[68],"regions":[69],"cortex":[71],"an":[73],"MRI":[74],"image":[76],"database":[77],"(N=102":[78],"scans).":[79],"Second,":[80],"these":[81,113],"high-dimensional":[82],"deformation":[83],"maps":[84],"are":[85],"used":[86,143],"transfer":[88],"within-subject":[89],"signals,":[91],"including":[92],"measures":[93],"gray":[95,123],"matter":[96,124],"distribution,":[97],"shape":[98],"asymmetries,":[99],"degenerative":[101],"rates,":[102],"common":[105],"anatomic":[106],"template":[107],"for":[108],"statistical":[109],"analysis.":[110],"illustrate":[112],"techniques":[114],"applications:":[117],"(1)":[118],"dynamic":[120],"patterns":[121],"loss":[125],"longitudinally":[127],"scanned":[128],"Alzheimer's":[129],"patients;":[131],"(2)":[133],"influences":[136,164],"structure.":[139],"extend":[141],"statistics":[142],"widely":[144],"behavioral":[146],"genetics":[147],"manifolds.":[150],"Specifically,":[151],"introduce":[153],"methods":[154],"h-squared":[157],"distributed":[158],"random":[159],"fields":[160],"map":[162],"hereditary":[163]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}