{"id":"https://openalex.org/W3004123276","doi":"https://doi.org/10.1109/iros40897.2019.8968207","title":"Automated Sorting of Rare Cells Based on Autofocusing Visual Feedback in Fluorescence Microscopy","display_name":"Automated Sorting of Rare Cells Based on Autofocusing Visual Feedback in Fluorescence Microscopy","publication_year":2019,"publication_date":"2019-11-01","ids":{"openalex":"https://openalex.org/W3004123276","doi":"https://doi.org/10.1109/iros40897.2019.8968207","mag":"3004123276"},"language":"en","primary_location":{"id":"doi:10.1109/iros40897.2019.8968207","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iros40897.2019.8968207","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085591477","display_name":"Kailun Bai","orcid":null},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Kailun Bai","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101471798","display_name":"Huaping Wang","orcid":"https://orcid.org/0000-0001-8440-3402"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huaping Wang","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011265988","display_name":"Qing Shi","orcid":"https://orcid.org/0009-0009-6112-0309"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Shi","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101779242","display_name":"Zhiqiang Zheng","orcid":"https://orcid.org/0000-0001-7077-5635"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiqiang Zheng","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101921364","display_name":"Juan Cui","orcid":"https://orcid.org/0000-0002-4025-4641"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juan Cui","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089797365","display_name":"Tao Sun","orcid":"https://orcid.org/0000-0003-1599-3466"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tao Sun","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100617912","display_name":"Qiang Huang","orcid":"https://orcid.org/0000-0001-5269-4161"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiang Huang","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076392384","display_name":"Paolo Dario","orcid":"https://orcid.org/0000-0001-9489-0056"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Paolo Dario","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065569192","display_name":"Toshio Fukuda","orcid":"https://orcid.org/0000-0002-3885-7152"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Toshio Fukuda","raw_affiliation_strings":["Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA"],"affiliations":[{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology,Beijing,CHINA,100081","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, CHINA","institution_ids":["https://openalex.org/I125839683"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5085591477"],"corresponding_institution_ids":["https://openalex.org/I125839683"],"apc_list":null,"apc_paid":null,"fwci":0.5356,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.73088244,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"1567","last_page":"1572"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11897","display_name":"Digital Holography and Microscopy","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sorting","display_name":"Sorting","score":0.7248312830924988},{"id":"https://openalex.org/keywords/cell-sorting","display_name":"Cell sorting","score":0.683718204498291},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6134475469589233},{"id":"https://openalex.org/keywords/flexibility","display_name":"Flexibility (engineering)","score":0.5717103481292725},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5290573835372925},{"id":"https://openalex.org/keywords/markov-random-field","display_name":"Markov random field","score":0.49857497215270996},{"id":"https://openalex.org/keywords/fluorescence-microscope","display_name":"Fluorescence microscope","score":0.4806848466396332},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.45888787508010864},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3514806032180786},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.35049259662628174},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.24516195058822632},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.21073919534683228},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.20243364572525024},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.15714216232299805},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.15236032009124756},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.140453040599823},{"id":"https://openalex.org/keywords/flow-cytometry","display_name":"Flow cytometry","score":0.12301865220069885},{"id":"https://openalex.org/keywords/molecular-biology","display_name":"Molecular biology","score":0.11009332537651062}],"concepts":[{"id":"https://openalex.org/C111696304","wikidata":"https://www.wikidata.org/wiki/Q2303697","display_name":"Sorting","level":2,"score":0.7248312830924988},{"id":"https://openalex.org/C2778630268","wikidata":"https://www.wikidata.org/wiki/Q17113277","display_name":"Cell sorting","level":3,"score":0.683718204498291},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6134475469589233},{"id":"https://openalex.org/C2780598303","wikidata":"https://www.wikidata.org/wiki/Q65921492","display_name":"Flexibility (engineering)","level":2,"score":0.5717103481292725},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5290573835372925},{"id":"https://openalex.org/C2778045648","wikidata":"https://www.wikidata.org/wiki/Q176827","display_name":"Markov random field","level":4,"score":0.49857497215270996},{"id":"https://openalex.org/C169274487","wikidata":"https://www.wikidata.org/wiki/Q840211","display_name":"Fluorescence microscope","level":3,"score":0.4806848466396332},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.45888787508010864},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3514806032180786},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.35049259662628174},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.24516195058822632},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.21073919534683228},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.20243364572525024},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15714216232299805},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.15236032009124756},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.140453040599823},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.12301865220069885},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.11009332537651062},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/iros40897.2019.8968207","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iros40897.2019.8968207","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1506219486","https://openalex.org/W1564973143","https://openalex.org/W1965311582","https://openalex.org/W2042210471","https://openalex.org/W2051147120","https://openalex.org/W2051572649","https://openalex.org/W2081098523","https://openalex.org/W2085446806","https://openalex.org/W2090643222","https://openalex.org/W2097099938","https://openalex.org/W2099395513","https://openalex.org/W2102649152","https://openalex.org/W2104716980","https://openalex.org/W2104839086","https://openalex.org/W2109591733","https://openalex.org/W2130727558","https://openalex.org/W2138552528","https://openalex.org/W2145556773","https://openalex.org/W2248288568","https://openalex.org/W2263306484","https://openalex.org/W2322683803","https://openalex.org/W2336174601","https://openalex.org/W2473719885","https://openalex.org/W6675048312","https://openalex.org/W6703459709"],"related_works":["https://openalex.org/W2739612537","https://openalex.org/W2349174696","https://openalex.org/W2360241746","https://openalex.org/W4313041667","https://openalex.org/W4391974410","https://openalex.org/W3026340973","https://openalex.org/W191145631","https://openalex.org/W2976895339","https://openalex.org/W2065781758","https://openalex.org/W2025408439"],"abstract_inverted_index":{"The":[0,136],"research":[1,11],"on":[2,70,146],"rare":[3,58,158],"cells":[4,159,161,172],"makes":[5],"a":[6,65,168],"significant":[7],"contribution":[8],"to":[9,106,129],"biology":[10],"and":[12,34,44,110,131,140,180,189],"medical":[13,190],"treatment":[14],"for":[15,57,87,187],"the":[16,133],"application":[17],"of":[18,92,115,170],"diagnostic":[19],"operation":[20],"as":[21,23,47,49],"well":[22,48],"prognoses":[24],"treatment.":[25],"Therefore,":[26],"sorting":[27,38],"them":[28],"from":[29,100],"heterogeneous":[30],"mixtures":[31],"is":[32,85,104,127,185],"crucial":[33],"valuable.":[35],"Traditional":[36],"cell":[37,66],"methods":[39],"featured":[40],"with":[41,177],"poor":[42],"purity":[43,179],"recovery":[45,182],"rate":[46],"limited":[50],"flexibility,":[51],"which":[52,184],"are":[53,143],"not":[54],"ideal":[55],"approaches":[56],"type.":[59],"In":[60],"this":[61],"paper,":[62],"we":[63],"proposed":[64,86],"screening":[67],"method":[68,84,103,126],"based":[69,124],"automated":[71],"microrobotic":[72],"aspiration-and-placement":[73],"strategy":[74],"under":[75],"fluorescence":[76],"microscope.":[77],"An":[78],"innovative":[79],"autofocusing":[80],"visual":[81],"feedback":[82],"(AVF)":[83],"precise":[88],"three-dimensional":[89],"(3D)":[90],"locating":[91,125,139],"target":[93],"cells.":[94,135],"For":[95,117],"depth":[96,99],"detection,":[97],"multiple":[98],"defocus":[101],"(MDFD)":[102],"adopted":[105],"solve":[107],"symmetry":[108],"problem":[109],"attain":[111],"an":[112],"average":[113],"accuracy":[114],"97.07%.":[116],"planar":[118],"locating,":[119],"Markov":[120],"random":[121],"field":[122],"(MRF)":[123],"utilized":[128],"separate":[130],"locate":[132],"overlapped":[134],"end":[137],"actuator":[138],"real-time":[141],"tracking":[142],"performed":[144],"relying":[145],"normalized":[147],"cross-correlation":[148],"(NCC)":[149],"method.":[150],"Experiential":[151],"results":[152],"show":[153],"that":[154],"our":[155],"system":[156],"collects":[157],"(100":[160],"ml":[162],"<sup":[163,174],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[164,175],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">-1</sup>":[165,176],")":[166],"at":[167],"speed":[169],"5":[171],"min":[173],"90%":[178],"75%":[181],"rate,":[183],"valuable":[186],"biological":[188],"application.":[191]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}