{"id":"https://openalex.org/W2552605651","doi":"https://doi.org/10.1109/ijcnn.2016.7727315","title":"A novel homeostatic plasticity model realized by random fluctuations in excitatory synapses","display_name":"A novel homeostatic plasticity model realized by random fluctuations in excitatory synapses","publication_year":2016,"publication_date":"2016-07-01","ids":{"openalex":"https://openalex.org/W2552605651","doi":"https://doi.org/10.1109/ijcnn.2016.7727315","mag":"2552605651"},"language":"en","primary_location":{"id":"doi:10.1109/ijcnn.2016.7727315","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ijcnn.2016.7727315","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 International Joint Conference on Neural Networks (IJCNN)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068667478","display_name":"Takashi Matsubara","orcid":"https://orcid.org/0000-0003-0642-4800"},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takashi Matsubara","raw_affiliation_strings":["Graduate School of System Informatics, Kobe University, Hyogo, Japan"],"affiliations":[{"raw_affiliation_string":"Graduate School of System Informatics, Kobe University, Hyogo, Japan","institution_ids":["https://openalex.org/I65837984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023847482","display_name":"Kuniaki Uehara","orcid":"https://orcid.org/0000-0002-7160-3752"},"institutions":[{"id":"https://openalex.org/I65837984","display_name":"Kobe University","ror":"https://ror.org/03tgsfw79","country_code":"JP","type":"education","lineage":["https://openalex.org/I65837984"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kuniaki Uehara","raw_affiliation_strings":["Graduate School of System Informatics, Kobe University, Hyogo, Japan"],"affiliations":[{"raw_affiliation_string":"Graduate School of System Informatics, Kobe University, Hyogo, Japan","institution_ids":["https://openalex.org/I65837984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068667478"],"corresponding_institution_ids":["https://openalex.org/I65837984"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10902687,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":null,"first_page":"1060","last_page":"1067"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/homeostatic-plasticity","display_name":"Homeostatic plasticity","score":0.9506675004959106},{"id":"https://openalex.org/keywords/synaptic-scaling","display_name":"Synaptic scaling","score":0.8621658086776733},{"id":"https://openalex.org/keywords/hebbian-theory","display_name":"Hebbian theory","score":0.8158912658691406},{"id":"https://openalex.org/keywords/metaplasticity","display_name":"Metaplasticity","score":0.8101541996002197},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"Synaptic plasticity","score":0.7729634046554565},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.7579245567321777},{"id":"https://openalex.org/keywords/nonsynaptic-plasticity","display_name":"Nonsynaptic plasticity","score":0.7535874843597412},{"id":"https://openalex.org/keywords/premovement-neuronal-activity","display_name":"Premovement neuronal activity","score":0.5862010717391968},{"id":"https://openalex.org/keywords/excitatory-postsynaptic-potential","display_name":"Excitatory postsynaptic potential","score":0.5784832835197449},{"id":"https://openalex.org/keywords/homosynaptic-plasticity","display_name":"Homosynaptic plasticity","score":0.5753443241119385},{"id":"https://openalex.org/keywords/neuroplasticity","display_name":"Neuroplasticity","score":0.539150059223175},{"id":"https://openalex.org/keywords/synaptic-augmentation","display_name":"Synaptic augmentation","score":0.43705466389656067},{"id":"https://openalex.org/keywords/biological-neural-network","display_name":"Biological neural network","score":0.43668442964553833},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4211776852607727},{"id":"https://openalex.org/keywords/plasticity","display_name":"Plasticity","score":0.41038933396339417},{"id":"https://openalex.org/keywords/inhibitory-postsynaptic-potential","display_name":"Inhibitory postsynaptic potential","score":0.24904519319534302},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.14243105053901672},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1182793378829956},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.1111009418964386}],"concepts":[{"id":"https://openalex.org/C5687787","wikidata":"https://www.wikidata.org/wiki/Q5889850","display_name":"Homeostatic plasticity","level":5,"score":0.9506675004959106},{"id":"https://openalex.org/C117718741","wikidata":"https://www.wikidata.org/wiki/Q7662041","display_name":"Synaptic scaling","level":5,"score":0.8621658086776733},{"id":"https://openalex.org/C111437709","wikidata":"https://www.wikidata.org/wiki/Q1277874","display_name":"Hebbian theory","level":3,"score":0.8158912658691406},{"id":"https://openalex.org/C194973443","wikidata":"https://www.wikidata.org/wiki/Q1420291","display_name":"Metaplasticity","level":4,"score":0.8101541996002197},{"id":"https://openalex.org/C98229152","wikidata":"https://www.wikidata.org/wiki/Q1551556","display_name":"Synaptic plasticity","level":3,"score":0.7729634046554565},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7579245567321777},{"id":"https://openalex.org/C26410512","wikidata":"https://www.wikidata.org/wiki/Q3906363","display_name":"Nonsynaptic plasticity","level":5,"score":0.7535874843597412},{"id":"https://openalex.org/C74254510","wikidata":"https://www.wikidata.org/wiki/Q7240508","display_name":"Premovement neuronal activity","level":2,"score":0.5862010717391968},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.5784832835197449},{"id":"https://openalex.org/C83119035","wikidata":"https://www.wikidata.org/wiki/Q17030659","display_name":"Homosynaptic plasticity","level":5,"score":0.5753443241119385},{"id":"https://openalex.org/C47611674","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Neuroplasticity","level":2,"score":0.539150059223175},{"id":"https://openalex.org/C95293801","wikidata":"https://www.wikidata.org/wiki/Q7662035","display_name":"Synaptic augmentation","level":4,"score":0.43705466389656067},{"id":"https://openalex.org/C118403218","wikidata":"https://www.wikidata.org/wiki/Q43283","display_name":"Biological neural network","level":2,"score":0.43668442964553833},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4211776852607727},{"id":"https://openalex.org/C79186407","wikidata":"https://www.wikidata.org/wiki/Q472074","display_name":"Plasticity","level":2,"score":0.41038933396339417},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.24904519319534302},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.14243105053901672},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1182793378829956},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.1111009418964386},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/ijcnn.2016.7727315","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ijcnn.2016.7727315","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 International Joint Conference on Neural Networks (IJCNN)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320315567","display_name":"Kayamori Foundation of Informational Science","ror":null},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1514853588","https://openalex.org/W1733248925","https://openalex.org/W1798313689","https://openalex.org/W1884265787","https://openalex.org/W1963806203","https://openalex.org/W1975401441","https://openalex.org/W1980574091","https://openalex.org/W1982864908","https://openalex.org/W1983553517","https://openalex.org/W1986246844","https://openalex.org/W2005073618","https://openalex.org/W2009782005","https://openalex.org/W2027896245","https://openalex.org/W2038511109","https://openalex.org/W2039655932","https://openalex.org/W2047535883","https://openalex.org/W2054856866","https://openalex.org/W2063062105","https://openalex.org/W2065546903","https://openalex.org/W2066046187","https://openalex.org/W2066563704","https://openalex.org/W2087824537","https://openalex.org/W2088947792","https://openalex.org/W2091116794","https://openalex.org/W2095484045","https://openalex.org/W2099347739","https://openalex.org/W2102744370","https://openalex.org/W2103594871","https://openalex.org/W2128378732","https://openalex.org/W2132753014","https://openalex.org/W2145036121","https://openalex.org/W2147101007","https://openalex.org/W2148389554","https://openalex.org/W2151542182","https://openalex.org/W2152807601","https://openalex.org/W2157239334","https://openalex.org/W2158014445","https://openalex.org/W2160361560","https://openalex.org/W2168976498","https://openalex.org/W2185212694","https://openalex.org/W2203294387","https://openalex.org/W2319723740","https://openalex.org/W4254059493"],"related_works":["https://openalex.org/W1986719288","https://openalex.org/W2348453215","https://openalex.org/W2203294387","https://openalex.org/W2401732305","https://openalex.org/W2040128952","https://openalex.org/W2078170624","https://openalex.org/W2946673189","https://openalex.org/W2075289911","https://openalex.org/W2003729768","https://openalex.org/W2914678996"],"abstract_inverted_index":{"Homeostatic":[0],"plasticity":[1,24,46,111,125,132,168,191],"in":[2,12,143,189],"mammalian":[3],"central":[4],"nervous":[5],"system":[6],"is":[7,27,77,100],"considered":[8],"to":[9,29,194],"maintain":[10],"activity":[11,26,56,99,145,180],"neuronal":[13,25,55,98,144,155,163,179],"circuits":[14],"within":[15],"a":[16,51,62,83,106,115,123,172],"functional":[17],"range.":[18],"In":[19],"the":[20,48,80,89,92],"absence":[21],"of":[22,50,65,82,91,109,174,178,198],"homeostatic":[23,45,116,175,190],"prone":[28],"be":[30,105],"destabilized":[31],"because":[32],"correlation-based":[33],"synaptic":[34,59,75,110,124,148,167],"modification,":[35],"Hebbian":[36,131],"plasticity,":[37,176],"induces":[38],"positive":[39],"feedback":[40],"change.":[41],"Several":[42],"studies":[43],"on":[44,61,162],"assumed":[47],"existence":[49],"process":[52],"for":[53],"monitoring":[54],"and":[57,88,121,130,136,192,196],"adjusting":[58,147],"efficacy":[60,76],"time":[63],"scale":[64],"hours,":[66],"but":[67,157],"its":[68],"biological":[69],"mechanism":[70],"still":[71],"remains":[72],"unclear.":[73],"Excitatory":[74],"associated":[78],"with":[79],"size":[81,90],"post-synaptic":[84],"element,":[85],"dendritic":[86,93],"spine,":[87],"spine":[94],"fluctuates":[95],"even":[96],"after":[97],"silenced.":[101],"These":[102],"fluctuations":[103,129,151,184],"could":[104],"non-Hebbian":[107],"form":[108,173],"that":[112,138],"serves":[113],"such":[114],"function.":[117],"This":[118],"study":[119],"proposed":[120,166],"analyzed":[122],"model":[126,169],"incorporating":[127],"random":[128,183],"at":[133],"excitatory":[134],"synapses,":[135],"found":[137],"it":[139],"prevents":[140],"excessive":[141],"changes":[142],"by":[146],"efficacy.":[149],"Random":[150],"do":[152],"not":[153],"monitor":[154],"activity,":[156],"their":[158],"relative":[159],"influence":[160],"depends":[161],"activity.":[164],"The":[165],"acts":[170],"as":[171],"regardless":[177],"monitoring.":[181],"Thus,":[182],"play":[185],"an":[186],"important":[187],"role":[188],"contribute":[193],"development":[195],"functions":[197],"neural":[199],"networks.":[200]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
