{"id":"https://openalex.org/W3206107434","doi":"https://doi.org/10.1109/iisa52424.2021.9555561","title":"Deep Learning for Bone Metastasis Localisation in Nuclear Imaging data of Breast Cancer Patients","display_name":"Deep Learning for Bone Metastasis Localisation in Nuclear Imaging data of Breast Cancer Patients","publication_year":2021,"publication_date":"2021-07-12","ids":{"openalex":"https://openalex.org/W3206107434","doi":"https://doi.org/10.1109/iisa52424.2021.9555561","mag":"3206107434"},"language":"en","primary_location":{"id":"doi:10.1109/iisa52424.2021.9555561","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iisa52424.2021.9555561","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 12th International Conference on Information, Intelligence, Systems & Applications (IISA)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077526481","display_name":"Serafeim Moustakidis","orcid":"https://orcid.org/0000-0002-1090-2177"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Serafeim Moustakidis","raw_affiliation_strings":["AIDEAS OU, Narva 5, Tallinm, Estonia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDEAS OU, Narva 5, Tallinm, Estonia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075098110","display_name":"Athanasios Siouras","orcid":"https://orcid.org/0000-0002-7654-0543"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Athanasios Siouras","raw_affiliation_strings":["AIDEAS OU, Narva 5, Tallinm, Estonia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AIDEAS OU, Narva 5, Tallinm, Estonia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089706575","display_name":"\u039d\u03b9\u03ba\u03cc\u03bb\u03b1\u03bf\u03c2 \u03a0\u03b1\u03c0\u03b1\u03bd\u03b4\u03c1\u03b9\u03b1\u03bd\u03cc\u03c2","orcid":"https://orcid.org/0000-0001-5416-1991"},"institutions":[{"id":"https://openalex.org/I145722265","display_name":"University of Thessaly","ror":"https://ror.org/04v4g9h31","country_code":"GR","type":"education","lineage":["https://openalex.org/I145722265"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Nikolaos Papandrianos","raw_affiliation_strings":["Faculty of Technology, Geopolis Campus, University of Thessaly, Larissa-Trikala Ring Road, Larissa, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Technology, Geopolis Campus, University of Thessaly, Larissa-Trikala Ring Road, Larissa, Greece","institution_ids":["https://openalex.org/I145722265"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012632769","display_name":"Charis Ntakolia","orcid":"https://orcid.org/0000-0001-9780-9815"},"institutions":[{"id":"https://openalex.org/I4210115397","display_name":"University Mental Health Research Institute","ror":"https://ror.org/02d439m40","country_code":"GR","type":"education","lineage":["https://openalex.org/I4210115397"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Charis Ntakolia","raw_affiliation_strings":["University Mental Health Research Institute, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Mental Health Research Institute, Athens, Greece","institution_ids":["https://openalex.org/I4210115397"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037965915","display_name":"Elpiniki I. Papageorgiou","orcid":"https://orcid.org/0000-0003-2498-9661"},"institutions":[{"id":"https://openalex.org/I145722265","display_name":"University of Thessaly","ror":"https://ror.org/04v4g9h31","country_code":"GR","type":"education","lineage":["https://openalex.org/I145722265"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Elpiniki Papageorgiou","raw_affiliation_strings":["Faculty of Technology, Geopolis Campus, University of Thessaly, Larissa-Trikala Ring Road, Larissa, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Technology, Geopolis Campus, University of Thessaly, Larissa-Trikala Ring Road, Larissa, Greece","institution_ids":["https://openalex.org/I145722265"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7879,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.85593625,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.6108282804489136},{"id":"https://openalex.org/keywords/metastasis","display_name":"Metastasis","score":0.525393545627594},{"id":"https://openalex.org/keywords/bone-imaging","display_name":"Bone imaging","score":0.5133563876152039},{"id":"https://openalex.org/keywords/bone-metastasis","display_name":"Bone metastasis","score":0.499600887298584},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4716205894947052},{"id":"https://openalex.org/keywords/breast-cancer-metastasis","display_name":"Breast cancer metastasis","score":0.41175520420074463},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3798399567604065},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3274855613708496},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.31249213218688965},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.15409672260284424}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6108282804489136},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.525393545627594},{"id":"https://openalex.org/C2909260394","wikidata":"https://www.wikidata.org/wiki/Q1928938","display_name":"Bone imaging","level":2,"score":0.5133563876152039},{"id":"https://openalex.org/C2777783956","wikidata":"https://www.wikidata.org/wiki/Q848085","display_name":"Bone metastasis","level":4,"score":0.499600887298584},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4716205894947052},{"id":"https://openalex.org/C2993589390","wikidata":"https://www.wikidata.org/wiki/Q12859063","display_name":"Breast cancer metastasis","level":5,"score":0.41175520420074463},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3798399567604065},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3274855613708496},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.31249213218688965},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15409672260284424}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/iisa52424.2021.9555561","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iisa52424.2021.9555561","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 12th International Conference on Information, Intelligence, Systems & Applications (IISA)","raw_type":"proceedings-article"},{"id":"pmh:oai:ir.lib.uth.gr:11615/76812","is_oa":false,"landing_page_url":"http://hdl.handle.net/11615/76812","pdf_url":null,"source":{"id":"https://openalex.org/S4306400243","display_name":"University of Thessaly Institutional Repository (University of Thessaly)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I145722265","host_organization_name":"University of Thessaly","host_organization_lineage":["https://openalex.org/I145722265"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IISA 2021 - 12th International Conference on Information, Intelligence, Systems and Applications","raw_type":"conferenceItem"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6600000262260437,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1958999316","https://openalex.org/W1997126111","https://openalex.org/W2000894286","https://openalex.org/W2010134822","https://openalex.org/W2022806012","https://openalex.org/W2033524909","https://openalex.org/W2038773012","https://openalex.org/W2108361166","https://openalex.org/W2139372524","https://openalex.org/W2166383248","https://openalex.org/W2254289098","https://openalex.org/W2488012015","https://openalex.org/W2585907770","https://openalex.org/W2594919434","https://openalex.org/W2612478849","https://openalex.org/W2770397194","https://openalex.org/W2804845349","https://openalex.org/W2808399363","https://openalex.org/W2946074429","https://openalex.org/W2965014579","https://openalex.org/W2971445890","https://openalex.org/W2974010802","https://openalex.org/W2977158709","https://openalex.org/W3003510818","https://openalex.org/W3005061589","https://openalex.org/W3012087752","https://openalex.org/W3043289003","https://openalex.org/W3046103539","https://openalex.org/W3049521066","https://openalex.org/W3092312060","https://openalex.org/W3095455471","https://openalex.org/W3102254678","https://openalex.org/W3104401316","https://openalex.org/W3128638061","https://openalex.org/W3133661165","https://openalex.org/W3180134609","https://openalex.org/W4249216321","https://openalex.org/W4287826091","https://openalex.org/W6640761988","https://openalex.org/W6737556521","https://openalex.org/W6775451124","https://openalex.org/W6785808489","https://openalex.org/W6786229539","https://openalex.org/W6791237859"],"related_works":["https://openalex.org/W4298087892","https://openalex.org/W3160437261","https://openalex.org/W4254256614","https://openalex.org/W60055582","https://openalex.org/W2392688306","https://openalex.org/W2570537891","https://openalex.org/W2027683842","https://openalex.org/W2918051428","https://openalex.org/W4321371981","https://openalex.org/W2010835587"],"abstract_inverted_index":{"Bone":[0],"scintigraphy":[1,202,292],"is":[2,33,77,204],"a":[3,42,117,127,141,159,165,205],"popular":[4],"method":[5],"for":[6,47,226],"the":[7,19,24,29,36,48,66,71,79,122,131,134,145,154,177,182,189,217,242,249,265,287],"diagnosis":[8],"of":[9,45,50,68,111,124,133,147,167,184,191,195,221,234,245,251,264,290],"bone":[10,27,38,55,60,62,75,99,185,227,282,291],"metastasis":[11,105,186,228,283],"that":[12,208],"typically":[13],"occurs":[14],"when":[15],"cancer":[16,69,76,89,93,104,236],"cells":[17],"from":[18,87],"primary":[20],"tumor":[21],"relocate":[22],"to":[23,70,84,152,216],"bone.":[25,72],"In":[26],"scintigraphy,":[28],"whole":[30],"patient\u2019s":[31],"body":[32],"scanned":[34],"and":[35,57,157,197,254,260],"generated":[37],"scan":[39],"visualization":[40],"provides":[41],"valuable":[43],"source":[44],"information":[46],"evaluation":[49],"various":[51],"bone-related":[52],"pathologies,":[53],"including":[54],"inflammation":[56],"fractures,":[58],"nonmalignant":[59],"lesions,":[61],"infections,":[63],"or":[64,103],"even":[65],"spread":[67],"?n":[73],"particular,":[74],"among":[78],"most":[80],"frequently":[81],"appeared":[82],"diseases":[83],"patients":[85],"suffering":[86],"metastatic":[88],"such":[90],"as":[91,140],"breast":[92,235],"patients.":[94,237],"However,":[95],"hot":[96,113,199],"spots":[97,114,200],"in":[98,130,144,176,201,230,281],"scans":[100],"indicating":[101],"inflammations":[102],"can":[106,115],"be":[107,116],"misleading.":[108],"Accurate":[109],"detection":[110,247],"pathological":[112,196],"very":[118],"challenging":[119],"procedure,":[120],"with":[121,181],"experience":[123],"clinicians":[125],"playing":[126],"critical":[128],"role":[129],"interpretation":[132,146,289],"images.":[135],"Artificial":[136],"intelligence":[137],"has":[138,209],"emerged":[139],"key":[142],"enabler":[143],"medical":[148],"imaging":[149,232],"being":[150],"able":[151],"model":[153],"aforementioned":[155],"uncertainties":[156],"providing":[158],"reliable":[160],"automated":[161],"solution.":[162],"So":[163],"far,":[164],"number":[166],"convolutional":[168],"neural":[169],"networks":[170,225],"(CNN)-based":[171],"techniques":[172],"have":[173],"been":[174,211],"proposed":[175,266,276],"recent":[178,255],"literature":[179],"coping":[180],"problem":[183],"classification.":[187],"To":[188],"best":[190],"our":[192],"knowledge,":[193],"localization":[194,229,284],"degenerative":[198],"images":[203],"scientific":[206],"area":[207],"not":[210],"explored.":[212],"This":[213],"paper":[214],"contributes":[215],"first":[218],"ever":[219],"deployment":[220],"advanced":[222],"deep":[223],"learning":[224],"nuclear":[231],"data":[233],"The":[238,262,275],"methodology":[239,267,277],"relies":[240],"on":[241],"latest":[243],"advances":[244],"object":[246],"via":[248],"use":[250],"two":[252],"powerful":[253],"models":[256],"(scaled":[257],"YOLO":[258],"v4":[259],"Detectron2).":[261],"efficacy":[263],"was":[268],"demonstrated":[269],"utilizing":[270],"an":[271],"extensive":[272],"experimentation":[273],"setup.":[274],"demonstrates":[278],"unique":[279],"potential":[280],"therefore":[285],"facilitating":[286],"clinical":[288],"scans.":[293]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1}],"updated_date":"2026-08-12T07:12:00.856984","created_date":"2021-10-25T00:00:00"}