{"id":"https://openalex.org/W2985728021","doi":"https://doi.org/10.1109/iisa.2019.8900755","title":"InteGene: An Integer Linear Programming Tool for Discovering Approximate Gene Clusters","display_name":"InteGene: An Integer Linear Programming Tool for Discovering Approximate Gene Clusters","publication_year":2019,"publication_date":"2019-07-01","ids":{"openalex":"https://openalex.org/W2985728021","doi":"https://doi.org/10.1109/iisa.2019.8900755","mag":"2985728021"},"language":"en","primary_location":{"id":"doi:10.1109/iisa.2019.8900755","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iisa.2019.8900755","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 10th International Conference on Information, Intelligence, Systems and Applications (IISA)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003763271","display_name":"Princess Danielle V. Florendo","orcid":null},"institutions":[{"id":"https://openalex.org/I5791819","display_name":"University of the Philippines Manila","ror":"https://ror.org/01rrczv41","country_code":"PH","type":"education","lineage":["https://openalex.org/I103911934","https://openalex.org/I5791819"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"Princess Danielle V. Florendo","raw_affiliation_strings":["Department of Physical Sciences and Mathematics, University of the Philippines Manila, Manila, Philippines"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Sciences and Mathematics, University of the Philippines Manila, Manila, Philippines","institution_ids":["https://openalex.org/I5791819"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086938101","display_name":"Geoffrey A. Solano","orcid":"https://orcid.org/0000-0002-4223-1355"},"institutions":[{"id":"https://openalex.org/I5791819","display_name":"University of the Philippines Manila","ror":"https://ror.org/01rrczv41","country_code":"PH","type":"education","lineage":["https://openalex.org/I103911934","https://openalex.org/I5791819"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"Geoffrey A. Solano","raw_affiliation_strings":["Department of Physical Sciences and Mathematics, University of the Philippines Manila, Manila, Philippines"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Sciences and Mathematics, University of the Philippines Manila, Manila, Philippines","institution_ids":["https://openalex.org/I5791819"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I5791819"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.21538675,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":null,"first_page":"1","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.9882000088691711,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/integer-programming","display_name":"Integer programming","score":0.6742890477180481},{"id":"https://openalex.org/keywords/linear-programming","display_name":"Linear programming","score":0.6431012153625488},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.6173580884933472},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5907909870147705},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5416737794876099},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.540790319442749},{"id":"https://openalex.org/keywords/linear-programming-relaxation","display_name":"Linear programming relaxation","score":0.47232550382614136},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4662697911262512},{"id":"https://openalex.org/keywords/relaxation","display_name":"Relaxation (psychology)","score":0.4572010934352875},{"id":"https://openalex.org/keywords/cluster","display_name":"Cluster (spacecraft)","score":0.45208799839019775},{"id":"https://openalex.org/keywords/time-complexity","display_name":"Time complexity","score":0.4413454532623291},{"id":"https://openalex.org/keywords/java","display_name":"Java","score":0.43673020601272583},{"id":"https://openalex.org/keywords/integer","display_name":"Integer (computer science)","score":0.41448983550071716},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.41421768069267273},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.39777302742004395},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.35822129249572754},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3392506241798401},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.23345455527305603},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.19170817732810974},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.19126081466674805}],"concepts":[{"id":"https://openalex.org/C56086750","wikidata":"https://www.wikidata.org/wiki/Q6042592","display_name":"Integer programming","level":2,"score":0.6742890477180481},{"id":"https://openalex.org/C41045048","wikidata":"https://www.wikidata.org/wiki/Q202843","display_name":"Linear programming","level":2,"score":0.6431012153625488},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.6173580884933472},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5907909870147705},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5416737794876099},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.540790319442749},{"id":"https://openalex.org/C25360446","wikidata":"https://www.wikidata.org/wiki/Q1512771","display_name":"Linear programming relaxation","level":3,"score":0.47232550382614136},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4662697911262512},{"id":"https://openalex.org/C2776029896","wikidata":"https://www.wikidata.org/wiki/Q3935810","display_name":"Relaxation (psychology)","level":2,"score":0.4572010934352875},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.45208799839019775},{"id":"https://openalex.org/C311688","wikidata":"https://www.wikidata.org/wiki/Q2393193","display_name":"Time complexity","level":2,"score":0.4413454532623291},{"id":"https://openalex.org/C548217200","wikidata":"https://www.wikidata.org/wiki/Q251","display_name":"Java","level":2,"score":0.43673020601272583},{"id":"https://openalex.org/C97137487","wikidata":"https://www.wikidata.org/wiki/Q729138","display_name":"Integer (computer science)","level":2,"score":0.41448983550071716},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.41421768069267273},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39777302742004395},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.35822129249572754},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3392506241798401},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.23345455527305603},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19170817732810974},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.19126081466674805},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/iisa.2019.8900755","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iisa.2019.8900755","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 10th International Conference on Information, Intelligence, Systems and Applications (IISA)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1480741490","https://openalex.org/W1517399014","https://openalex.org/W1520138033","https://openalex.org/W1530654453","https://openalex.org/W1553810969","https://openalex.org/W1579467649","https://openalex.org/W1592614241","https://openalex.org/W1902486992","https://openalex.org/W1994466654","https://openalex.org/W1995106824","https://openalex.org/W2022846158","https://openalex.org/W2044007697","https://openalex.org/W2050902903","https://openalex.org/W2075986427","https://openalex.org/W2077474256","https://openalex.org/W2095387858","https://openalex.org/W2099785809","https://openalex.org/W2108621157","https://openalex.org/W2113904019","https://openalex.org/W2122000666","https://openalex.org/W2153974716","https://openalex.org/W2161316685"],"related_works":["https://openalex.org/W4252122881","https://openalex.org/W134055995","https://openalex.org/W2009796757","https://openalex.org/W4302819359","https://openalex.org/W1973873435","https://openalex.org/W4244487479","https://openalex.org/W1963627056","https://openalex.org/W2047683846","https://openalex.org/W2044902158","https://openalex.org/W2109912052"],"abstract_inverted_index":{"The":[0,113],"opportunity":[1],"of":[2,15,20,25,64,85,100,145],"finding":[3,65],"conserved":[4,49],"segments":[5,46],"in":[6,71,75,110],"different":[7,21,26,32,72],"species":[8,33],"has":[9],"increased":[10],"with":[11],"the":[12,62,86,95,118,129,133,137,139],"increasing":[13],"availability":[14],"completely":[16],"sequenced":[17],"genomes.":[18],"Similarity":[19],"parts":[22],"or":[23,52],"regions":[24],"genomes":[27],"suggests":[28],"evolutionary":[29],"relationships":[30],"among":[31],"and":[34,120,123,147],"might":[35],"foretell":[36],"functional":[37],"roles":[38],"which":[39,150],"prevented":[40],"genes":[41,66],"to":[42,92],"separate.":[43],"These":[44],"similar":[45],"are":[47,68],"called":[48],"gene":[50,53],"clusters":[51,141],"clusters.":[54],"Approximate":[55],"Gene":[56],"Cluster":[57],"Discovery":[58],"Problem":[59],"(AGCDP)":[60],"is":[61,78,90],"problem":[63],"that":[67],"kept":[69],"together":[70],"species.":[73],"Presented":[74],"this":[76],"study":[77,96],"an":[79],"Integer":[80],"Linear":[81],"Programming":[82],"(ILP)":[83],"formulation":[84],"AGCDP.":[87],"Since":[88],"ILP":[89],"proven":[91],"be":[93,108,152],"NP-complete,":[94],"also":[97],"made":[98],"use":[99],"LP":[101],"Relaxation":[102],"since":[103],"linear":[104],"programming":[105],"problems":[106],"can":[107,135,151],"solved":[109],"polynomial":[111],"time.":[112],"software":[114],"used":[115],"Java":[116],"for":[117,125,155],"interface":[119],"other":[121],"functionalities":[122],"R":[124],"solving":[126],"ILP.":[127],"InteGene,":[128],"tool":[130],"produced":[131],"by":[132],"study,":[134],"provide":[136],"user":[138],"best":[140],"given":[142],"a":[143],"set":[144],"data":[146],"input":[148],"constraints":[149],"further":[153],"tested":[154],"biological":[156],"significance.":[157]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}