{"id":"https://openalex.org/W2789304147","doi":"https://doi.org/10.1109/iisa.2017.8316389","title":"Pathway-based human disease clustering tool using self-organizing maps","display_name":"Pathway-based human disease clustering tool using self-organizing maps","publication_year":2017,"publication_date":"2017-08-01","ids":{"openalex":"https://openalex.org/W2789304147","doi":"https://doi.org/10.1109/iisa.2017.8316389","mag":"2789304147"},"language":"en","primary_location":{"id":"doi:10.1109/iisa.2017.8316389","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iisa.2017.8316389","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 8th International Conference on Information, Intelligence, Systems &amp; Applications (IISA)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025324503","display_name":"James-Andrew Sarmiento","orcid":null},"institutions":[{"id":"https://openalex.org/I5791819","display_name":"University of the Philippines Manila","ror":"https://ror.org/01rrczv41","country_code":"PH","type":"education","lineage":["https://openalex.org/I103911934","https://openalex.org/I5791819"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"James-Andrew R. Sarmiento","raw_affiliation_strings":["Department of Physical Sciences and Mathematics, University of the Philippines, Manila"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Sciences and Mathematics, University of the Philippines, Manila","institution_ids":["https://openalex.org/I5791819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036042109","display_name":"Angelyn R. Lao","orcid":"https://orcid.org/0000-0003-3028-9610"},"institutions":[{"id":"https://openalex.org/I5996616","display_name":"De La Salle University","ror":"https://ror.org/04xftk194","country_code":"PH","type":"education","lineage":["https://openalex.org/I5996616"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"Angelyn Lao","raw_affiliation_strings":["Mathematics Department, De La Salle University, Manila"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mathematics Department, De La Salle University, Manila","institution_ids":["https://openalex.org/I5996616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086938101","display_name":"Geoffrey A. Solano","orcid":"https://orcid.org/0000-0002-4223-1355"},"institutions":[{"id":"https://openalex.org/I5791819","display_name":"University of the Philippines Manila","ror":"https://ror.org/01rrczv41","country_code":"PH","type":"education","lineage":["https://openalex.org/I103911934","https://openalex.org/I5791819"]},{"id":"https://openalex.org/I87074743","display_name":"University of the Philippines Diliman","ror":"https://ror.org/03tbh6y23","country_code":"PH","type":"education","lineage":["https://openalex.org/I103911934","https://openalex.org/I87074743"]}],"countries":["PH"],"is_corresponding":false,"raw_author_name":"Geoffrey A. Solano","raw_affiliation_strings":["Department of Computer Science, University of the Philippines-Diliman","Department of Physical Sciences and Mathematics, University of the Philippines, Manila"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of the Philippines-Diliman","institution_ids":["https://openalex.org/I87074743"]},{"raw_affiliation_string":"Department of Physical Sciences and Mathematics, University of the Philippines, Manila","institution_ids":["https://openalex.org/I5791819"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.7002,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.90572172,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"5","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6975829601287842},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6928364038467407},{"id":"https://openalex.org/keywords/self-organizing-map","display_name":"Self-organizing map","score":0.47643715143203735},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4170333743095398},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.33204385638237}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6975829601287842},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6928364038467407},{"id":"https://openalex.org/C111168008","wikidata":"https://www.wikidata.org/wiki/Q1136838","display_name":"Self-organizing map","level":3,"score":0.47643715143203735},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4170333743095398},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33204385638237}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/iisa.2017.8316389","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iisa.2017.8316389","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 8th International Conference on Information, Intelligence, Systems &amp; Applications (IISA)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1040120543","https://openalex.org/W1977921870","https://openalex.org/W2026565396","https://openalex.org/W2062533676","https://openalex.org/W2108172198","https://openalex.org/W2110802877","https://openalex.org/W2114718748","https://openalex.org/W2135445920","https://openalex.org/W2138898937","https://openalex.org/W2160873061","https://openalex.org/W2163910794","https://openalex.org/W2173280396","https://openalex.org/W2399571647","https://openalex.org/W2883460582","https://openalex.org/W2995133973","https://openalex.org/W2996370053","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2137873534","https://openalex.org/W1884786007","https://openalex.org/W4237337822","https://openalex.org/W1990590916","https://openalex.org/W2125478079","https://openalex.org/W2359998128","https://openalex.org/W2465801081","https://openalex.org/W2036813961","https://openalex.org/W2244828372","https://openalex.org/W2361151334"],"abstract_inverted_index":{"Understanding":[0],"how":[1],"different":[2,170],"diseases":[3,178],"are":[4],"related":[5],"to":[6,63,70,84,106,139,168],"one":[7],"another":[8],"based":[9],"on":[10,73],"their":[11],"shared":[12,71],"pathways":[13,75],"could":[14],"provide":[15],"new":[16],"insights":[17],"into":[18],"disease":[19],"etiology":[20],"and":[21,57,65,157],"classification.":[22],"The":[23],"exploration":[24],"of":[25,55,76,111,121,130,172,176],"disease-disease":[26],"associations":[27],"by":[28,52,135],"using":[29],"a":[30,98,112,119,140,148,162],"system-level":[31],"biological":[32],"data":[33,39,138,183],"is":[34,40,97,104,118,161],"made":[35],"possible":[36],"as":[37,47,147],"the":[38,49,74,86,91,109,173,180],"now":[41],"publicly":[42],"available":[43,87,181],"via":[44,154],"databases":[45,89],"such":[46],"in":[48,133],"database":[50],"maintained":[51],"Kyoto":[53],"Encyclopedia":[54],"Genes":[56],"Genomes":[58],"(KEGG).":[59],"By":[60],"being":[61],"able":[62,83,105],"cluster":[64,152],"visualize":[66,108],"relationships":[67,175],"with":[68],"respect":[69],"entities":[72],"human":[77,177],"diseases,":[78],"researchers":[79],"would":[80],"be":[81,145],"fully":[82],"use":[85],"pathway":[88,182],"for":[90,100,151],"said":[92],"scientific":[93],"purposes.":[94],"Thus,":[95],"there":[96],"need":[99],"an":[101],"algorithm":[102],"that":[103,125,164],"effectively":[107],"topology":[110],"multi-dimensional":[113,137],"data.":[114],"Self-Organizing":[115],"Map":[116],"(SOM)":[117],"type":[120],"artificial":[122],"neural":[123],"network":[124],"employs":[126],"unsupervised":[127],"learning":[128],"capable":[129],"discovering":[131],"patterns":[132],"datasets":[134],"reducing":[136],"low-dimensional":[141],"representation.":[142],"SOM":[143],"can":[144],"used":[146],"pre-processing":[149],"step":[150],"analysis":[153],"k-means":[155],"clustering":[156],"hierarchical":[158],"clustering.":[159],"PathSOM":[160],"software":[163],"uses":[165],"self-organizing":[166],"maps":[167],"create":[169],"visualizations":[171],"underlying":[174],"utilizing":[179],"from":[184],"KEGG.":[185]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}
