{"id":"https://openalex.org/W2032939405","doi":"https://doi.org/10.1109/iembs.2011.6091404","title":"Continuous Multiorgan Variability monitoring in critically ill patients — Complexity science at the bedside","display_name":"Continuous Multiorgan Variability monitoring in critically ill patients — Complexity science at the bedside","publication_year":2011,"publication_date":"2011-08-01","ids":{"openalex":"https://openalex.org/W2032939405","doi":"https://doi.org/10.1109/iembs.2011.6091404","mag":"2032939405","pmid":"https://pubmed.ncbi.nlm.nih.gov/22255584"},"language":"en","primary_location":{"id":"doi:10.1109/iembs.2011.6091404","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6091404","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061090915","display_name":"Andrew Seely","orcid":"https://orcid.org/0000-0002-6459-8801"},"institutions":[{"id":"https://openalex.org/I2800722420","display_name":"Ottawa Hospital","ror":"https://ror.org/03c62dg59","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2800722420"]},{"id":"https://openalex.org/I4388482656","display_name":"Ottawa Hospital Research Institute","ror":"https://ror.org/05jtef216","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I153718931","https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"A. J. E. Seely","raw_affiliation_strings":["Ottawa Hospital ResearchInstitute, University of Ottawa. aseely@ohri.ca","Ottawa Hospital Research Institute (OHRI)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ottawa Hospital ResearchInstitute, University of Ottawa. aseely@ohri.ca","institution_ids":["https://openalex.org/I2800722420"]},{"raw_affiliation_string":"Ottawa Hospital Research Institute (OHRI)","institution_ids":["https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070534749","display_name":"G. C. Green","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. C. Green","raw_affiliation_strings":["Therapeutic Monitoring Systems"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Therapeutic Monitoring Systems","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073083131","display_name":"Andrea Bravi","orcid":null},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I2800722420","display_name":"Ottawa Hospital","ror":"https://ror.org/03c62dg59","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2800722420"]},{"id":"https://openalex.org/I4388482656","display_name":"Ottawa Hospital Research Institute","ror":"https://ror.org/05jtef216","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I153718931","https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"A. Bravi","raw_affiliation_strings":["University of Ottawa","Ottawa Hospital Research Institute (OHRI);"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Ottawa","institution_ids":["https://openalex.org/I153718931"]},{"raw_affiliation_string":"Ottawa Hospital Research Institute (OHRI);","institution_ids":["https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1778,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.88456304,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"8","issue":null,"first_page":"5503","last_page":"5506"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13248","display_name":"Healthcare Technology and Patient Monitoring","score":0.9593999981880188,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/critically-ill","display_name":"Critically ill","score":0.7697845697402954},{"id":"https://openalex.org/keywords/critical-illness","display_name":"Critical illness","score":0.5907377004623413},{"id":"https://openalex.org/keywords/continuous-monitoring","display_name":"Continuous monitoring","score":0.5866921544075012},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.5866865515708923},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4560352563858032},{"id":"https://openalex.org/keywords/remote-patient-monitoring","display_name":"Remote patient monitoring","score":0.41802000999450684},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4111824631690979},{"id":"https://openalex.org/keywords/risk-analysis","display_name":"Risk analysis (engineering)","score":0.4088791608810425},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.16233929991722107},{"id":"https://openalex.org/keywords/operations-management","display_name":"Operations management","score":0.08648234605789185}],"concepts":[{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.7697845697402954},{"id":"https://openalex.org/C2993568657","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critical illness","level":3,"score":0.5907377004623413},{"id":"https://openalex.org/C2776902269","wikidata":"https://www.wikidata.org/wiki/Q5165493","display_name":"Continuous monitoring","level":2,"score":0.5866921544075012},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5866865515708923},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4560352563858032},{"id":"https://openalex.org/C175079658","wikidata":"https://www.wikidata.org/wiki/Q7312165","display_name":"Remote patient monitoring","level":2,"score":0.41802000999450684},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4111824631690979},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.4088791608810425},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.16233929991722107},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.08648234605789185},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003422","descriptor_name":"Critical Care","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/iembs.2011.6091404","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6091404","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:22255584","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22255584","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":86,"referenced_works":["https://openalex.org/W633594338","https://openalex.org/W1209070443","https://openalex.org/W1487019984","https://openalex.org/W1498727162","https://openalex.org/W1526062633","https://openalex.org/W1862394037","https://openalex.org/W1964694080","https://openalex.org/W1973184644","https://openalex.org/W1983678221","https://openalex.org/W1984061770","https://openalex.org/W1985005579","https://openalex.org/W1986986113","https://openalex.org/W1989415069","https://openalex.org/W1990332066","https://openalex.org/W1996084889","https://openalex.org/W2002853103","https://openalex.org/W2005388553","https://openalex.org/W2017046795","https://openalex.org/W2017821362","https://openalex.org/W2018366225","https://openalex.org/W2020822256","https://openalex.org/W2020870533","https://openalex.org/W2021044602","https://openalex.org/W2022279170","https://openalex.org/W2024773227","https://openalex.org/W2026746053","https://openalex.org/W2028553295","https://openalex.org/W2029170996","https://openalex.org/W2036056901","https://openalex.org/W2036302750","https://openalex.org/W2038476114","https://openalex.org/W2038569109","https://openalex.org/W2042938532","https://openalex.org/W2044475085","https://openalex.org/W2050803595","https://openalex.org/W2053016376","https://openalex.org/W2053853941","https://openalex.org/W2056503107","https://openalex.org/W2063282974","https://openalex.org/W2065616337","https://openalex.org/W2068625127","https://openalex.org/W2071559069","https://openalex.org/W2071900848","https://openalex.org/W2076081817","https://openalex.org/W2077204677","https://openalex.org/W2078206416","https://openalex.org/W2079133700","https://openalex.org/W2082227074","https://openalex.org/W2087212896","https://openalex.org/W2095233676","https://openalex.org/W2100317815","https://openalex.org/W2101046053","https://openalex.org/W2104688429","https://openalex.org/W2105349897","https://openalex.org/W2107544524","https://openalex.org/W2110429989","https://openalex.org/W2112400936","https://openalex.org/W2114119838","https://openalex.org/W2116068981","https://openalex.org/W2123186407","https://openalex.org/W2123837685","https://openalex.org/W2125120517","https://openalex.org/W2129738329","https://openalex.org/W2130465845","https://openalex.org/W2133589238","https://openalex.org/W2139676856","https://openalex.org/W2147012385","https://openalex.org/W2153842705","https://openalex.org/W2158976222","https://openalex.org/W2160359556","https://openalex.org/W2161915117","https://openalex.org/W2163127764","https://openalex.org/W2164411137","https://openalex.org/W2165633274","https://openalex.org/W2167263515","https://openalex.org/W2169437634","https://openalex.org/W2285072859","https://openalex.org/W2322707526","https://openalex.org/W2327586644","https://openalex.org/W2478227765","https://openalex.org/W2964631455","https://openalex.org/W2993383518","https://openalex.org/W3003725138","https://openalex.org/W3025756148","https://openalex.org/W3150363102","https://openalex.org/W4248666415"],"related_works":["https://openalex.org/W1788304568","https://openalex.org/W2588498999","https://openalex.org/W2161123588","https://openalex.org/W1988708075","https://openalex.org/W1565682083","https://openalex.org/W2805528247","https://openalex.org/W2739327955","https://openalex.org/W2160827975","https://openalex.org/W4321192578","https://openalex.org/W4230721384"],"abstract_inverted_index":{"Complex":[0],"systems":[1],"science":[2],"has":[3,17],"led":[4,19],"to":[5,20,23,25,54,64],"valuable":[6],"insights":[7],"regarding":[8],"the":[9,28,56,61,103,106],"care":[10,24],"and":[11,51,75,105],"understanding":[12],"of":[13,60,72,89,93,98,100,108],"critical":[14],"illness,":[15],"but":[16],"not":[18],"fundamental":[21],"improvements":[22],"date.":[26],"Realizing":[27],"fact":[29],"that":[30,82],"there":[31],"is":[32],"inherent":[33],"uncertainty":[34],"in":[35,102,115],"patient":[36],"trajectory,":[37],"we":[38,83],"have":[39],"developed":[40],"Continuous":[41],"Individual":[42],"Multiorgan":[43],"Variability":[44],"Analysis":[45],"(CIMVA)":[46],"as":[47],"a":[48],"tool":[49],"theoretically":[50],"practically":[52],"designed":[53],"track":[55],"systemic":[57],"emergent":[58],"properties":[59],"host":[62],"response":[63],"injury":[65],"or":[66],"infection.":[67],"We":[68],"present":[69],"an":[70],"overview":[71],"CIMVA":[73],"software,":[74],"discuss":[76],"four":[77],"separate":[78],"potential":[79],"clinical":[80],"applications":[81],"are":[84,113],"evaluating;":[85],"including":[86],"early":[87],"detection":[88],"infection,":[90],"better":[91],"prediction":[92],"extubation":[94],"failure,":[95],"continuous":[96],"monitoring":[97],"severity":[99],"illness":[101],"ICU,":[104],"evaluation":[107],"cardiopulmonary":[109],"fitness.":[110],"Future":[111],"challenges":[112],"discussed":[114],"conclusion.":[116]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2016-06-24T00:00:00"}