{"id":"https://openalex.org/W1988209995","doi":"https://doi.org/10.1109/iembs.2011.6091347","title":"Optimization-based dosimetry planning for brachytherapy","display_name":"Optimization-based dosimetry planning for brachytherapy","publication_year":2011,"publication_date":"2011-08-01","ids":{"openalex":"https://openalex.org/W1988209995","doi":"https://doi.org/10.1109/iembs.2011.6091347","mag":"1988209995","pmid":"https://pubmed.ncbi.nlm.nih.gov/22255601"},"language":"en","primary_location":{"id":"doi:10.1109/iembs.2011.6091347","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6091347","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100669568","display_name":"Tianhao Zhang","orcid":"https://orcid.org/0000-0003-0713-9526"},"institutions":[{"id":"https://openalex.org/I131944076","display_name":"Lawson Health Research Institute","ror":"https://ror.org/051gsh239","country_code":"CA","type":"funder","lineage":["https://openalex.org/I131944076"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Tianhao Zhang","raw_affiliation_strings":["Lawson Health Research Institute, 339 Windermere Road, London, ON, Canada. tzhang84@uwo.ca","Department of Electrical and Computer Engineering, UWO, London, ONT, Canada","CSTAR, Lawson Health Research Institute, London, ONT, Canada"],"affiliations":[{"raw_affiliation_string":"Lawson Health Research Institute, 339 Windermere Road, London, ON, Canada. tzhang84@uwo.ca","institution_ids":["https://openalex.org/I131944076"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, UWO, London, ONT, Canada","institution_ids":[]},{"raw_affiliation_string":"CSTAR, Lawson Health Research Institute, London, ONT, Canada","institution_ids":["https://openalex.org/I131944076"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032056508","display_name":"Rajni V. Patel","orcid":"https://orcid.org/0000-0003-3431-4617"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Patel","raw_affiliation_strings":["CSTAR, the Department of Electrical and Computer Engineering and the Department of Surgery, UWO, Canada"],"affiliations":[{"raw_affiliation_string":"CSTAR, the Department of Electrical and Computer Engineering and the Department of Surgery, UWO, Canada","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100669568"],"corresponding_institution_ids":["https://openalex.org/I131944076"],"apc_list":null,"apc_paid":null,"fwci":0.3982,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.65821063,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"221","issue":null,"first_page":"5569","last_page":"5572"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.991100013256073,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.984000027179718,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dosimetry","display_name":"Dosimetry","score":0.9135951995849609},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6771031618118286},{"id":"https://openalex.org/keywords/brachytherapy","display_name":"Brachytherapy","score":0.6635301113128662},{"id":"https://openalex.org/keywords/plan","display_name":"Plan (archaeology)","score":0.6632049083709717},{"id":"https://openalex.org/keywords/radiation-treatment-planning","display_name":"Radiation treatment planning","score":0.5674715638160706},{"id":"https://openalex.org/keywords/medical-physics","display_name":"Medical physics","score":0.5318496227264404},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.44346392154693604},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.14656245708465576},{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.14334526658058167},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.13318327069282532},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.08871534466743469},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.08247485756874084}],"concepts":[{"id":"https://openalex.org/C75088862","wikidata":"https://www.wikidata.org/wiki/Q2291081","display_name":"Dosimetry","level":2,"score":0.9135951995849609},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6771031618118286},{"id":"https://openalex.org/C2777416452","wikidata":"https://www.wikidata.org/wiki/Q896687","display_name":"Brachytherapy","level":3,"score":0.6635301113128662},{"id":"https://openalex.org/C2776505523","wikidata":"https://www.wikidata.org/wiki/Q4785468","display_name":"Plan (archaeology)","level":2,"score":0.6632049083709717},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.5674715638160706},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.5318496227264404},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.44346392154693604},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.14656245708465576},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.14334526658058167},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13318327069282532},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.08871534466743469},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.08247485756874084},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.0},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001918","descriptor_name":"Brachytherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001918","descriptor_name":"Brachytherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001918","descriptor_name":"Brachytherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011874","descriptor_name":"Radiometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011874","descriptor_name":"Radiometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011874","descriptor_name":"Radiometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011880","descriptor_name":"Radiotherapy Planning, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/iembs.2011.6091347","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6091347","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:22255601","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22255601","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1525920326","https://openalex.org/W1989379939","https://openalex.org/W1995815526","https://openalex.org/W2064057265","https://openalex.org/W2115174476","https://openalex.org/W2139590107","https://openalex.org/W2139913352","https://openalex.org/W2142679343","https://openalex.org/W2144739674","https://openalex.org/W2150683838","https://openalex.org/W2153629629","https://openalex.org/W2158734599","https://openalex.org/W2185440705","https://openalex.org/W6677339510"],"related_works":["https://openalex.org/W2415632822","https://openalex.org/W2807885017","https://openalex.org/W328240141","https://openalex.org/W92931116","https://openalex.org/W2400699660","https://openalex.org/W2985431943","https://openalex.org/W2066925027","https://openalex.org/W2086196749","https://openalex.org/W2106662487","https://openalex.org/W2460936463"],"abstract_inverted_index":{"Algorithms":[0],"for":[1,5,34,58],"improving":[2],"dosimetry":[3,20,50],"plans":[4,54],"brachytherapy":[6],"procedures":[7],"have":[8],"been":[9],"developed.":[10],"In":[11],"particular,":[12],"the":[13,27,43],"algorithms":[14,44],"focus":[15],"on":[16],"creating":[17],"an":[18],"optimized":[19],"plan":[21,28],"automatically,":[22],"as":[23,25],"well":[24],"updating":[26],"in":[29,36,60],"real":[30],"time":[31],"to":[32],"compensate":[33],"errors":[35],"seed":[37],"placements.":[38],"The":[39,53],"overall":[40],"performance":[41],"of":[42],"is":[45],"compared":[46],"with":[47],"currently":[48],"existing":[49],"planning":[51],"software.":[52],"are":[55],"particularly":[56],"suited":[57],"use":[59],"robotics-assisted":[61],"procedures.":[62]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}