{"id":"https://openalex.org/W2012109890","doi":"https://doi.org/10.1109/iembs.2011.6091273","title":"Detection of malaria parasites in thick blood films","display_name":"Detection of malaria parasites in thick blood films","publication_year":2011,"publication_date":"2011-08-01","ids":{"openalex":"https://openalex.org/W2012109890","doi":"https://doi.org/10.1109/iembs.2011.6091273","mag":"2012109890","pmid":"https://pubmed.ncbi.nlm.nih.gov/22255496"},"language":"en","primary_location":{"id":"doi:10.1109/iembs.2011.6091273","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6091273","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050416546","display_name":"Matthias Elter","orcid":null},"institutions":[{"id":"https://openalex.org/I4210124274","display_name":"Fraunhofer Institute for Integrated Circuits","ror":"https://ror.org/024ape423","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210124274","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Matthias Elter","raw_affiliation_strings":["Fraunhofer Institute for Integrated Circuits IIS, Image Processing and Medical Engineering Department, Am Wolfsmantel 33, 91058 Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fraunhofer Institute for Integrated Circuits IIS, Image Processing and Medical Engineering Department, Am Wolfsmantel 33, 91058 Erlangen, Germany","institution_ids":["https://openalex.org/I4210124274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055423656","display_name":"Erik Haslmeyer","orcid":null},"institutions":[{"id":"https://openalex.org/I4210124274","display_name":"Fraunhofer Institute for Integrated Circuits","ror":"https://ror.org/024ape423","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210124274","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Erik Haslmeyer","raw_affiliation_strings":["Fraunhofer Institute for Integrated Circuits IIS, Image Processing and Medical Engineering Department, Am Wolfsmantel 33, 91058 Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fraunhofer Institute for Integrated Circuits IIS, Image Processing and Medical Engineering Department, Am Wolfsmantel 33, 91058 Erlangen, Germany","institution_ids":["https://openalex.org/I4210124274"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052111047","display_name":"Thorsten Zerfas","orcid":null},"institutions":[{"id":"https://openalex.org/I4210124274","display_name":"Fraunhofer Institute for Integrated Circuits","ror":"https://ror.org/024ape423","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210124274","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thorsten Zerfas","raw_affiliation_strings":["Fraunhofer Institute for Integrated Circuits IIS, Image Processing and Medical Engineering Department, Am Wolfsmantel 33, 91058 Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fraunhofer Institute for Integrated Circuits IIS, Image Processing and Medical Engineering Department, Am Wolfsmantel 33, 91058 Erlangen, Germany","institution_ids":["https://openalex.org/I4210124274"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2617,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.56652095,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"2011","issue":null,"first_page":"5140","last_page":"5144"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9865999817848206,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10616","display_name":"Smart Agriculture and AI","score":0.9736999869346619,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.837922990322113},{"id":"https://openalex.org/keywords/blood-film","display_name":"Blood film","score":0.6966485977172852},{"id":"https://openalex.org/keywords/stage","display_name":"Stage (stratigraphy)","score":0.6429698467254639},{"id":"https://openalex.org/keywords/blood-smear","display_name":"Blood smear","score":0.5922924280166626},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.5639646053314209},{"id":"https://openalex.org/keywords/plasmodium","display_name":"Plasmodium (life cycle)","score":0.4939647316932678},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.46757274866104126},{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.4626999497413635},{"id":"https://openalex.org/keywords/microscope","display_name":"Microscope","score":0.4311802089214325},{"id":"https://openalex.org/keywords/false-positive-rate","display_name":"False positive rate","score":0.4122082591056824},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.39360079169273376},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.36032217741012573},{"id":"https://openalex.org/keywords/parasite-hosting","display_name":"Parasite hosting","score":0.35761749744415283},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.323066771030426},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.2878526747226715},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2844012975692749},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2781721353530884}],"concepts":[{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.837922990322113},{"id":"https://openalex.org/C3018882108","wikidata":"https://www.wikidata.org/wiki/Q886475","display_name":"Blood film","level":3,"score":0.6966485977172852},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.6429698467254639},{"id":"https://openalex.org/C3017819844","wikidata":"https://www.wikidata.org/wiki/Q886475","display_name":"Blood smear","level":3,"score":0.5922924280166626},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.5639646053314209},{"id":"https://openalex.org/C2778675580","wikidata":"https://www.wikidata.org/wiki/Q614956","display_name":"Plasmodium (life cycle)","level":3,"score":0.4939647316932678},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.46757274866104126},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.4626999497413635},{"id":"https://openalex.org/C67649825","wikidata":"https://www.wikidata.org/wiki/Q196538","display_name":"Microscope","level":2,"score":0.4311802089214325},{"id":"https://openalex.org/C95922358","wikidata":"https://www.wikidata.org/wiki/Q5432725","display_name":"False positive rate","level":2,"score":0.4122082591056824},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.39360079169273376},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.36032217741012573},{"id":"https://openalex.org/C71928629","wikidata":"https://www.wikidata.org/wiki/Q804206","display_name":"Parasite hosting","level":2,"score":0.35761749744415283},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.323066771030426},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2878526747226715},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2844012975692749},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2781721353530884},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016778","descriptor_name":"Malaria, Falciparum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/iembs.2011.6091273","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6091273","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:22255496","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22255496","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:publica.fraunhofer.de:publica/374503","is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/374503","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"conference paper"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8399999737739563}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1571816072","https://openalex.org/W2013536196","https://openalex.org/W2022685900","https://openalex.org/W2033769372","https://openalex.org/W2040620478","https://openalex.org/W2044465660","https://openalex.org/W2044562217","https://openalex.org/W2054019556","https://openalex.org/W2055101873","https://openalex.org/W2074643865","https://openalex.org/W2077191558","https://openalex.org/W2090218170","https://openalex.org/W2102009083","https://openalex.org/W2118376687","https://openalex.org/W2126506130","https://openalex.org/W2132222410","https://openalex.org/W2140927567","https://openalex.org/W2153879951","https://openalex.org/W2159498975","https://openalex.org/W2171661133","https://openalex.org/W3217380390"],"related_works":["https://openalex.org/W2411199131","https://openalex.org/W2084516783","https://openalex.org/W2149347413","https://openalex.org/W2043005394","https://openalex.org/W2120900442","https://openalex.org/W1516000131","https://openalex.org/W137426367","https://openalex.org/W1754697043","https://openalex.org/W2143344700","https://openalex.org/W2902178069"],"abstract_inverted_index":{"Malaria,":[0],"caused":[1],"by":[2],"a":[3,31,38,99,104],"blood":[4,33,49],"parasite":[5],"of":[6,12,30,45,53,66,77,89,101,107,125],"the":[7,18,22,42,54,75,86,90,117,123],"genus":[8],"plasmodium,":[9],"kills":[10],"millions":[11],"people":[13],"each":[14],"year.":[15],"According":[16],"to":[17,80],"World":[19],"Health":[20],"Organization,":[21],"standard":[23],"for":[24,41,122,129],"malaria":[25,131],"diagnosis":[26],"is":[27,57,120],"microscopic":[28],"examination":[29],"stained":[32],"film.":[34],"We":[35],"have":[36],"developed":[37],"two-stage":[39],"algorithm":[40,94,119],"automatic":[43],"detection":[44,60,87],"plasmodia":[46,97],"in":[47],"thick":[48],"films.":[50],"The":[51,71,93],"focus":[52],"first":[55,91],"stage":[56,73],"on":[58],"high":[59,64],"sensitivity":[61,88,100],"while":[62,84],"accepting":[63],"numbers":[65],"false-positive":[67,78,109],"detections":[68,79,110],"per":[69,111],"image.":[70,112],"second":[72],"reduces":[74],"number":[76,106],"an":[81,126],"acceptable":[82],"level":[83],"maintaining":[85],"stage.":[92],"can":[95],"detect":[96],"at":[98],"0.97":[102],"with":[103],"mean":[105],"0.8":[108],"Our":[113],"results":[114],"indicate":[115],"that":[116],"proposed":[118],"suitable":[121],"development":[124],"automated":[127],"microscope":[128],"computer-aided":[130],"screening.":[132]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}