{"id":"https://openalex.org/W2025224004","doi":"https://doi.org/10.1109/iembs.2011.6091012","title":"A model of motoneuron behavior and muscle-force generation for sustained isometric contractions","display_name":"A model of motoneuron behavior and muscle-force generation for sustained isometric contractions","publication_year":2011,"publication_date":"2011-08-01","ids":{"openalex":"https://openalex.org/W2025224004","doi":"https://doi.org/10.1109/iembs.2011.6091012","mag":"2025224004","pmid":"https://pubmed.ncbi.nlm.nih.gov/22255235"},"language":"en","primary_location":{"id":"doi:10.1109/iembs.2011.6091012","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6091012","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012239734","display_name":"Paola Contessa","orcid":"https://orcid.org/0000-0002-8645-6783"},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"P. Contessa","raw_affiliation_strings":["Department of Information Engineering, University of Padova, Padova, Italy. contessa@bu.edu","Department of Information Engineering; University of Padova; Padova; Italy"],"affiliations":[{"raw_affiliation_string":"Department of Information Engineering, University of Padova, Padova, Italy. contessa@bu.edu","institution_ids":["https://openalex.org/I138689650"]},{"raw_affiliation_string":"Department of Information Engineering; University of Padova; Padova; Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114211892","display_name":"S. Hamid Nawab","orcid":null},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. H. Nawab","raw_affiliation_strings":["Department of Biomedical Engineering and Electrical and Computer Engineering, Boston University, Boston, MA, USA","Department of Biomedical Engineering and Electrical and Computer Engineering, Boston University, Boston, MA, 02215 USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Electrical and Computer Engineering, Boston University, Boston, MA, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Biomedical Engineering and Electrical and Computer Engineering, Boston University, Boston, MA, 02215 USA","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109957638","display_name":"Carlo J. De Luca","orcid":null},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. J. De Luca","raw_affiliation_strings":["NeuroMuscular Research Center, Boston University, Boston, MA, USA","Director of the NeuroMuscular Research Center, Boston University, Boston, MA 02215 USA"],"affiliations":[{"raw_affiliation_string":"NeuroMuscular Research Center, Boston University, Boston, MA, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Director of the NeuroMuscular Research Center, Boston University, Boston, MA 02215 USA","institution_ids":["https://openalex.org/I111088046"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5012239734"],"corresponding_institution_ids":["https://openalex.org/I138689650"],"apc_list":null,"apc_paid":null,"fwci":0.2098,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.56499791,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"2011","issue":null,"first_page":"4072","last_page":"4075"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10784","display_name":"Muscle activation and electromyography studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10784","display_name":"Muscle activation and electromyography studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10338","display_name":"Advanced Sensor and Energy Harvesting Materials","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/isometric-exercise","display_name":"Isometric exercise","score":0.9451133012771606},{"id":"https://openalex.org/keywords/muscle-fatigue","display_name":"Muscle fatigue","score":0.5496491193771362},{"id":"https://openalex.org/keywords/muscle-contraction","display_name":"Muscle contraction","score":0.5176980495452881},{"id":"https://openalex.org/keywords/contraction","display_name":"Contraction (grammar)","score":0.5023632049560547},{"id":"https://openalex.org/keywords/electromyography","display_name":"Electromyography","score":0.48977112770080566},{"id":"https://openalex.org/keywords/dorsum","display_name":"Dorsum","score":0.4496850371360779},{"id":"https://openalex.org/keywords/vastus-lateralis-muscle","display_name":"Vastus lateralis muscle","score":0.41538697481155396},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.3896075487136841},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.2975582480430603},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.21398866176605225},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"Skeletal muscle","score":0.12542009353637695},{"id":"https://openalex.org/keywords/physical-therapy","display_name":"Physical therapy","score":0.11333850026130676},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.08545646071434021}],"concepts":[{"id":"https://openalex.org/C103486182","wikidata":"https://www.wikidata.org/wiki/Q1216236","display_name":"Isometric exercise","level":2,"score":0.9451133012771606},{"id":"https://openalex.org/C2776874296","wikidata":"https://www.wikidata.org/wiki/Q6940317","display_name":"Muscle fatigue","level":3,"score":0.5496491193771362},{"id":"https://openalex.org/C2776050358","wikidata":"https://www.wikidata.org/wiki/Q127006","display_name":"Muscle contraction","level":2,"score":0.5176980495452881},{"id":"https://openalex.org/C163415756","wikidata":"https://www.wikidata.org/wiki/Q126473","display_name":"Contraction (grammar)","level":2,"score":0.5023632049560547},{"id":"https://openalex.org/C2777515770","wikidata":"https://www.wikidata.org/wiki/Q507369","display_name":"Electromyography","level":2,"score":0.48977112770080566},{"id":"https://openalex.org/C140530291","wikidata":"https://www.wikidata.org/wiki/Q1225063","display_name":"Dorsum","level":2,"score":0.4496850371360779},{"id":"https://openalex.org/C2776643329","wikidata":"https://www.wikidata.org/wiki/Q975459","display_name":"Vastus lateralis muscle","level":3,"score":0.41538697481155396},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3896075487136841},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.2975582480430603},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21398866176605225},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.12542009353637695},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.11333850026130676},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08545646071434021}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007537","descriptor_name":"Isometric Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007537","descriptor_name":"Isometric Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007537","descriptor_name":"Isometric Contraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D025461","descriptor_name":"Feedback, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025461","descriptor_name":"Feedback, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025461","descriptor_name":"Feedback, Physiological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/iembs.2011.6091012","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6091012","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:22255235","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22255235","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1809394698","https://openalex.org/W1996919407","https://openalex.org/W2001144437","https://openalex.org/W2008364237","https://openalex.org/W2017235581","https://openalex.org/W2034066231","https://openalex.org/W2047347032","https://openalex.org/W2052258664","https://openalex.org/W2056526300","https://openalex.org/W2076436446","https://openalex.org/W2098285915","https://openalex.org/W2113200940","https://openalex.org/W2131229150","https://openalex.org/W2148270081","https://openalex.org/W2259666366","https://openalex.org/W4247075498"],"related_works":["https://openalex.org/W2322261446","https://openalex.org/W2017681254","https://openalex.org/W2423632980","https://openalex.org/W2364553218","https://openalex.org/W2334954599","https://openalex.org/W2159324317","https://openalex.org/W2534579942","https://openalex.org/W2020864139","https://openalex.org/W2170492757","https://openalex.org/W2441671583"],"abstract_inverted_index":{"A":[0],"model":[1,95,126],"for":[2],"the":[3,25,28,35,57,78,84,87,92,109,116,128,153,160,168,173,180],"simulation":[4],"of":[5,31,38,69,83,91,111,119,130,142,179],"motoneuron":[6,29],"firing":[7,36,99],"behavior":[8,37,118],"and":[9,34,49,86,98,107,176],"muscle":[10,33,43,58,82,90,112,157,163],"force":[11,59,71,97,131],"during":[12,122,167],"sustained":[13,73,123],"constant-force":[14],"isometric":[15],"contractions":[16,72],"was":[17],"developed.":[18],"It":[19],"provides":[20],"a":[21,32,52,61,67],"non-linear":[22],"relationship":[23],"between":[24],"excitation":[26],"to":[27,55,140,172],"pool":[30],"motor":[39,120,146],"units;":[40],"it":[41,50],"implements":[42],"mechanical":[44,113,177],"changes":[45,114],"induced":[46],"by":[47],"fatigue":[48,134],"comprises":[51],"feedback":[53],"loop":[54],"maintain":[56],"at":[60,74,164],"given":[62],"target":[63],"level.":[64],"We":[65],"simulated":[66],"series":[68],"repeated":[70],"20%":[75],"MVC":[76],"with":[77,104,133],"first":[79,154],"dorsal":[80,155],"interosseous":[81,156],"hand":[85],"vastus":[88,161],"lateralis":[89,162],"thigh.":[93],"The":[94,125],"generates":[96],"behaviors":[100],"which":[101],"are":[102],"consistent":[103],"experimental":[105],"findings":[106],"underscores":[108],"influence":[110],"on":[115],"control":[117],"units":[121],"contractions.":[124],"predicts":[127],"increase":[129],"fluctuation":[132],"in":[135,152,159],"both":[136],"muscles,":[137],"likely":[138],"due":[139,171],"recruitment":[141],"high-threshold":[143],"high-amplitude":[144],"twitch":[145],"units.":[147],"Force":[148],"variability":[149],"is":[150],"greater":[151],"than":[158],"any":[165],"time":[166],"contraction":[169],"series,":[170],"different":[174],"electrical":[175],"properties":[178],"muscles.":[181]},"counts_by_year":[{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}