{"id":"https://openalex.org/W2052429960","doi":"https://doi.org/10.1109/iembs.2011.6090722","title":"Joint spatio-temporal registration and microvasculature segmentation of retinal angiogram sequences","display_name":"Joint spatio-temporal registration and microvasculature segmentation of retinal angiogram sequences","publication_year":2011,"publication_date":"2011-08-01","ids":{"openalex":"https://openalex.org/W2052429960","doi":"https://doi.org/10.1109/iembs.2011.6090722","mag":"2052429960","pmid":"https://pubmed.ncbi.nlm.nih.gov/22254878"},"language":"en","primary_location":{"id":"doi:10.1109/iembs.2011.6090722","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6090722","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059708976","display_name":"Shuoying Cao","orcid":null},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shuoying Cao","raw_affiliation_strings":["Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ. shuoying.cao@imperial.ac.uk","Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ. shuoying.cao@imperial.ac.uk","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027222571","display_name":"Anil A. Bharath","orcid":"https://orcid.org/0000-0001-8808-2714"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. Bharath","raw_affiliation_strings":["Bioengineering Department, Imperial College London, London, UK","Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084709068","display_name":"Kim H. Parker","orcid":"https://orcid.org/0000-0001-6971-0682"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K. Parker","raw_affiliation_strings":["Bioengineering Department, Imperial College London, London, UK","Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017222712","display_name":"Jeffrey Ng","orcid":"https://orcid.org/0000-0003-1430-3646"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Ng","raw_affiliation_strings":["Bioengineering Department, Imperial College London, London, UK","Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087611693","display_name":"Jonathan Arnold","orcid":"https://orcid.org/0000-0001-5845-1048"},"institutions":[{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Arnold","raw_affiliation_strings":["Charing Cross Hospital, Imperial College Healthcare NHS Trust, UK","Charing Cross Hospital, Imperial College Healthcare NHS Trust"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Charing Cross Hospital, Imperial College Healthcare NHS Trust, UK","institution_ids":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]},{"raw_affiliation_string":"Charing Cross Hospital, Imperial College Healthcare NHS Trust","institution_ids":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043385815","display_name":"Alison H. McGregor","orcid":"https://orcid.org/0000-0003-4672-332X"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. McGregor","raw_affiliation_strings":["Faculty of Medicine, Surgery and Cancer, Imperial College London, UK","Faculty of Medicine, Surgery and Cancer, Imperial College London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Surgery and Cancer, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Faculty of Medicine, Surgery and Cancer, Imperial College London","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102851058","display_name":"Adam M. Hill","orcid":"https://orcid.org/0000-0002-0579-5231"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. Hill","raw_affiliation_strings":["Bioengineering Department, Imperial College London, London, UK","Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering Department, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Bioengineering Department, Imperial College London, South Beddington Campus, London SW7 2AZ","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7152,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.64327799,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"1679","issue":null,"first_page":"2618","last_page":"2621"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9955000281333923,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9648000001907349,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7394876480102539},{"id":"https://openalex.org/keywords/joint","display_name":"Joint (building)","score":0.7115849852561951},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.669674813747406},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.61902916431427},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5687999129295349},{"id":"https://openalex.org/keywords/image-registration","display_name":"Image registration","score":0.4963265061378479},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.48922252655029297},{"id":"https://openalex.org/keywords/retinal","display_name":"Retinal","score":0.457976758480072},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.45071423053741455},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.18194836378097534},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.13804128766059875},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.10310161113739014},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.06371346116065979}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7394876480102539},{"id":"https://openalex.org/C18555067","wikidata":"https://www.wikidata.org/wiki/Q8375051","display_name":"Joint (building)","level":2,"score":0.7115849852561951},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.669674813747406},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.61902916431427},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5687999129295349},{"id":"https://openalex.org/C166704113","wikidata":"https://www.wikidata.org/wiki/Q861092","display_name":"Image registration","level":3,"score":0.4963265061378479},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.48922252655029297},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.457976758480072},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.45071423053741455},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18194836378097534},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.13804128766059875},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.10310161113739014},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.06371346116065979},{"id":"https://openalex.org/C170154142","wikidata":"https://www.wikidata.org/wiki/Q150737","display_name":"Architectural engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005451","descriptor_name":"Fluorescein Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005451","descriptor_name":"Fluorescein Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005451","descriptor_name":"Fluorescein Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/iembs.2011.6090722","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6090722","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:22254878","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22254878","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4399999976158142,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1579287100","https://openalex.org/W1844086758","https://openalex.org/W1967002721","https://openalex.org/W1990254675","https://openalex.org/W2016072915","https://openalex.org/W2057771956","https://openalex.org/W2075160183","https://openalex.org/W2085012886","https://openalex.org/W2085261163","https://openalex.org/W2094767167","https://openalex.org/W2133798182","https://openalex.org/W2141085506","https://openalex.org/W2157823657","https://openalex.org/W2162426307"],"related_works":["https://openalex.org/W4387265590","https://openalex.org/W1995904975","https://openalex.org/W1996130883","https://openalex.org/W2748574964","https://openalex.org/W3032712071","https://openalex.org/W4389019322","https://openalex.org/W2888483922","https://openalex.org/W3040090327","https://openalex.org/W2756647615","https://openalex.org/W1522196789"],"abstract_inverted_index":{"We":[0],"discuss":[1],"the":[2,75,79,102,106],"problem":[3],"of":[4,10,74,78,98,108],"2D+t":[5],"intra-":[6],"and":[7,92,110],"inter-sequential":[8],"registration":[9,16,45],"retinal":[11],"angiograms.":[12],"A":[13],"joint":[14,44],"spatio-temporal":[15],"algorithm":[17],"is":[18,38],"presented":[19],"based":[20],"on":[21],"a":[22,29,41],"RANSAC":[23],"(RANdom":[24],"SAmple":[25],"Consensus)":[26],"approach":[27],"incorporating":[28],"quadratic":[30],"model":[31],"to":[32,53,104],"describe":[33],"\"pairwise\"":[34],"image":[35],"homography.":[36],"This":[37,100],"incorporated":[39],"into":[40],"local-to-global":[42],"hierarchical":[43],"framework.":[46],"After":[47],"registration,":[48],"vessel":[49],"centrelines":[50,65,73,84],"are":[51,69],"segmented":[52,72],"subpixel":[54],"accuracy":[55],"by":[56],"applying":[57],"multi-scale":[58],"steerable":[59],"complex":[60],"wavelet":[61],"filters.":[62],"Frame-by-frame":[63],"microvascular":[64,83],"in":[66,85],"Regions-of-Interest":[67],"(ROIs)":[68],"evaluated":[70],"against":[71],"temporal":[76],"average":[77],"registered":[80,86],"sequences.":[81],"The":[82],"sequences":[87],"can":[88],"be":[89],"compared":[90],"intra-sequentially":[91],"inter-sequentially,":[93],"allowing":[94],"non-invasive":[95],"clinical":[96],"monitoring":[97],"micro-circulation.":[99],"has":[101],"potential":[103],"detect":[105],"presence":[107],"microemboli":[109],"pathological":[111],"structural":[112],"alterations.":[113]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}