{"id":"https://openalex.org/W2053375108","doi":"https://doi.org/10.1109/iembs.2011.6090705","title":"System identification of baroreflex response to mild lower body negative pressure","display_name":"System identification of baroreflex response to mild lower body negative pressure","publication_year":2011,"publication_date":"2011-08-01","ids":{"openalex":"https://openalex.org/W2053375108","doi":"https://doi.org/10.1109/iembs.2011.6090705","mag":"2053375108","pmid":"https://pubmed.ncbi.nlm.nih.gov/22254861"},"language":"en","primary_location":{"id":"doi:10.1109/iembs.2011.6090705","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6090705","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031141438","display_name":"Federico Aletti","orcid":"https://orcid.org/0000-0003-1472-837X"},"institutions":[{"id":"https://openalex.org/I93860229","display_name":"Politecnico di Milano","ror":"https://ror.org/01nffqt88","country_code":"IT","type":"education","lineage":["https://openalex.org/I93860229"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"F. Aletti","raw_affiliation_strings":["Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci 23, 20133 Milan, Italy. federico.aletti@polimi.it","Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 23, 20133 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci 23, 20133 Milan, Italy. federico.aletti@polimi.it","institution_ids":["https://openalex.org/I93860229"]},{"raw_affiliation_string":"Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 23, 20133 Milan, Italy","institution_ids":["https://openalex.org/I93860229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041008084","display_name":"Manuela Ferrario","orcid":"https://orcid.org/0000-0001-7371-3624"},"institutions":[{"id":"https://openalex.org/I93860229","display_name":"Politecnico di Milano","ror":"https://ror.org/01nffqt88","country_code":"IT","type":"education","lineage":["https://openalex.org/I93860229"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Ferrario","raw_affiliation_strings":["Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy","Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 23, 20133 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy","institution_ids":["https://openalex.org/I93860229"]},{"raw_affiliation_string":"Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 23, 20133 Milan, Italy","institution_ids":["https://openalex.org/I93860229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113845069","display_name":"Da Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I151746483","display_name":"University of Waterloo","ror":"https://ror.org/01aff2v68","country_code":"CA","type":"education","lineage":["https://openalex.org/I151746483"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Da Xu","raw_affiliation_strings":["Faculty of Applied Health Sciences, University of Waterloo, Waterloo, ONT, Canada","Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada"],"affiliations":[{"raw_affiliation_string":"Faculty of Applied Health Sciences, University of Waterloo, Waterloo, ONT, Canada","institution_ids":["https://openalex.org/I151746483"]},{"raw_affiliation_string":"Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada","institution_ids":["https://openalex.org/I151746483"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001538929","display_name":"Danielle K. Greaves","orcid":"https://orcid.org/0000-0001-5188-086X"},"institutions":[{"id":"https://openalex.org/I151746483","display_name":"University of Waterloo","ror":"https://ror.org/01aff2v68","country_code":"CA","type":"education","lineage":["https://openalex.org/I151746483"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"D. K. Greaves","raw_affiliation_strings":["Faculty of Applied Health Sciences, University of Waterloo, Waterloo, ONT, Canada","Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada"],"affiliations":[{"raw_affiliation_string":"Faculty of Applied Health Sciences, University of Waterloo, Waterloo, ONT, Canada","institution_ids":["https://openalex.org/I151746483"]},{"raw_affiliation_string":"Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada","institution_ids":["https://openalex.org/I151746483"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086962507","display_name":"J. Kevin Shoemaker","orcid":"https://orcid.org/0000-0002-6794-5979"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"K. J. Shoemaker","raw_affiliation_strings":["Faculty of Health Sciences, University of Western Ontario, London, Canada","Faculty of Health Sciences University of Western Ontario London Canada"],"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Faculty of Health Sciences University of Western Ontario London Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074126455","display_name":"Philippe Arbeille","orcid":"https://orcid.org/0000-0001-5372-8757"},"institutions":[{"id":"https://openalex.org/I110017253","display_name":"Universit\u00e9 de Tours","ror":"https://ror.org/02wwzvj46","country_code":"FR","type":"education","lineage":["https://openalex.org/I110017253"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P. Arbeille","raw_affiliation_strings":["Facult\u00e9 de M\u00e9decine, Universit\u00e9 de Tours, Tours, France"],"affiliations":[{"raw_affiliation_string":"Facult\u00e9 de M\u00e9decine, Universit\u00e9 de Tours, Tours, France","institution_ids":["https://openalex.org/I110017253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017502703","display_name":"S. Cerutti","orcid":"https://orcid.org/0000-0002-9607-8755"},"institutions":[{"id":"https://openalex.org/I93860229","display_name":"Politecnico di Milano","ror":"https://ror.org/01nffqt88","country_code":"IT","type":"education","lineage":["https://openalex.org/I93860229"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Cerutti","raw_affiliation_strings":["Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy","Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 23, 20133 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy","institution_ids":["https://openalex.org/I93860229"]},{"raw_affiliation_string":"Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 23, 20133 Milan, Italy","institution_ids":["https://openalex.org/I93860229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067797276","display_name":"Richard L. Hughson","orcid":"https://orcid.org/0000-0001-6915-2959"},"institutions":[{"id":"https://openalex.org/I151746483","display_name":"University of Waterloo","ror":"https://ror.org/01aff2v68","country_code":"CA","type":"education","lineage":["https://openalex.org/I151746483"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"R. L. Hughson","raw_affiliation_strings":["Faculty of Applied Health Sciences, University of Waterloo, Waterloo, ONT, Canada","Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada"],"affiliations":[{"raw_affiliation_string":"Faculty of Applied Health Sciences, University of Waterloo, Waterloo, ONT, Canada","institution_ids":["https://openalex.org/I151746483"]},{"raw_affiliation_string":"Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada","institution_ids":["https://openalex.org/I151746483"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012150223","display_name":"Giuseppe Baselli","orcid":"https://orcid.org/0000-0003-2978-1704"},"institutions":[{"id":"https://openalex.org/I93860229","display_name":"Politecnico di Milano","ror":"https://ror.org/01nffqt88","country_code":"IT","type":"education","lineage":["https://openalex.org/I93860229"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Baselli","raw_affiliation_strings":["Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy","Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 23, 20133 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Bioingegneria, Politecnico di Milano, Milan, Italy","institution_ids":["https://openalex.org/I93860229"]},{"raw_affiliation_string":"Dipartimento di Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 23, 20133 Milan, Italy","institution_ids":["https://openalex.org/I93860229"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5031141438"],"corresponding_institution_ids":["https://openalex.org/I93860229"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14731669,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"281","issue":null,"first_page":"2550","last_page":"2553"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/baroreflex","display_name":"Baroreflex","score":0.949792742729187},{"id":"https://openalex.org/keywords/baroreceptor","display_name":"Baroreceptor","score":0.8498150706291199},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.6884745359420776},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5204420685768127},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.4950672686100006},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.48295754194259644},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.39765262603759766},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.35938963294029236}],"concepts":[{"id":"https://openalex.org/C191237925","wikidata":"https://www.wikidata.org/wiki/Q808725","display_name":"Baroreflex","level":4,"score":0.949792742729187},{"id":"https://openalex.org/C79752029","wikidata":"https://www.wikidata.org/wiki/Q808732","display_name":"Baroreceptor","level":4,"score":0.8498150706291199},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.6884745359420776},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5204420685768127},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4950672686100006},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.48295754194259644},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.39765262603759766},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.35938963294029236}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017704","descriptor_name":"Baroreflex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017704","descriptor_name":"Baroreflex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017704","descriptor_name":"Baroreflex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/iembs.2011.6090705","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iembs.2011.6090705","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:22254861","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22254861","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:re.public.polimi.it:11311/608352","is_oa":false,"landing_page_url":"http://hdl.handle.net/11311/608352","pdf_url":null,"source":{"id":"https://openalex.org/S4306400312","display_name":"Virtual Community of Pathological Anatomy (University of Castilla La Mancha)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79189158","host_organization_name":"University of Castilla-La Mancha","host_organization_lineage":["https://openalex.org/I79189158"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8100000023841858,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W2013805612","https://openalex.org/W2056845527","https://openalex.org/W2067285354","https://openalex.org/W2087581395","https://openalex.org/W2098495280","https://openalex.org/W2101647345","https://openalex.org/W2108845381","https://openalex.org/W2163216194","https://openalex.org/W2277033845"],"related_works":["https://openalex.org/W2784470254","https://openalex.org/W2326594690","https://openalex.org/W2329025098","https://openalex.org/W1986472926","https://openalex.org/W2115073568","https://openalex.org/W2085223436","https://openalex.org/W2417049126","https://openalex.org/W2158021652","https://openalex.org/W2417226223","https://openalex.org/W2898266525"],"abstract_inverted_index":{"The":[0,78],"effect":[1],"of":[2,12,44,59,62,70,81,88,97,106,117,137,140,145],"mild":[3,45,75],"lower":[4],"body":[5],"negative":[6],"pressure":[7,15,86],"(LBNP)":[8],"on":[9],"baroreflex":[10,24,91,124,147],"control":[11],"arterial":[13,33,63,85,90,107,118,123],"blood":[14],"(ABP)":[16],"has":[17],"long":[18],"been":[19],"thought":[20],"to":[21,67,74,94,129,151],"affect":[22],"cardiopulmonary":[23,65,146],"only,":[25],"although":[26],"recent":[27],"studies":[28],"have":[29],"pointed":[30],"out":[31],"that":[32,103],"baroreceptors":[34,108],"may":[35,109],"be":[36,110,130],"transiently":[37],"unloaded":[38],"too":[39],"after":[40],"the":[41,55,60,89,104,131,135,143],"rapid":[42],"onset":[43],"LBNP.":[46],"This":[47],"paper":[48],"presents":[49],"a":[50],"spectral":[51],"decomposition":[52],"method":[53],"for":[54],"black":[56],"box":[57],"identification":[58],"contribution":[61,93],"and":[64,83,87],"baroreflexes":[66],"beat-by-beat":[68,138],"variability":[69,96],"ABP":[71,98],"in":[72,134],"response":[73,116],"LBNP":[76],"levels.":[77],"significant":[79],"decrease":[80],"mean":[82],"diastolic":[84],"mediated":[92,125,148],"overall":[95],"which":[99],"was":[100],"found,":[101],"suggested":[102],"unloading":[105],"reflected":[111],"by":[112],"an":[113],"altered":[114],"dynamic":[115],"baroreflex,":[119],"too.":[120],"In":[121],"addition,":[122],"modulations":[126],"were":[127],"found":[128],"main":[132],"player":[133],"modulation":[136],"fluctuations":[139],"ABP,":[141],"while":[142],"role":[144],"responses":[149],"appeared":[150],"contribute":[152],"very":[153],"little.":[154]},"counts_by_year":[],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}