{"id":"https://openalex.org/W3007840124","doi":"https://doi.org/10.1109/icsai48974.2019.9010118","title":"Aided Diagnosis of Alzheimer's Disease Based on Structural Magnetic Resonance Imaging","display_name":"Aided Diagnosis of Alzheimer's Disease Based on Structural Magnetic Resonance Imaging","publication_year":2019,"publication_date":"2019-11-01","ids":{"openalex":"https://openalex.org/W3007840124","doi":"https://doi.org/10.1109/icsai48974.2019.9010118","mag":"3007840124"},"language":"en","primary_location":{"id":"doi:10.1109/icsai48974.2019.9010118","is_oa":false,"landing_page_url":"https://doi.org/10.1109/icsai48974.2019.9010118","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 6th International Conference on Systems and Informatics (ICSAI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100450785","display_name":"Xi Liu","orcid":"https://orcid.org/0000-0002-1110-2382"},"institutions":[{"id":"https://openalex.org/I179026463","display_name":"Beijing Technology and Business University","ror":"https://ror.org/013e0zm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I179026463"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xi Liu","raw_affiliation_strings":["School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China"],"affiliations":[{"raw_affiliation_string":"School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China","institution_ids":["https://openalex.org/I179026463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100701606","display_name":"Yu Wang","orcid":"https://orcid.org/0000-0002-1607-5475"},"institutions":[{"id":"https://openalex.org/I179026463","display_name":"Beijing Technology and Business University","ror":"https://ror.org/013e0zm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I179026463"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Wang","raw_affiliation_strings":["School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China"],"affiliations":[{"raw_affiliation_string":"School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China","institution_ids":["https://openalex.org/I179026463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034105161","display_name":"Changyang Fu","orcid":null},"institutions":[{"id":"https://openalex.org/I179026463","display_name":"Beijing Technology and Business University","ror":"https://ror.org/013e0zm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I179026463"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changyang Fu","raw_affiliation_strings":["School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China"],"affiliations":[{"raw_affiliation_string":"School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China","institution_ids":["https://openalex.org/I179026463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031296104","display_name":"Hongbing Xiao","orcid":"https://orcid.org/0000-0003-3432-1200"},"institutions":[{"id":"https://openalex.org/I179026463","display_name":"Beijing Technology and Business University","ror":"https://ror.org/013e0zm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I179026463"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongbing Xiao","raw_affiliation_strings":["School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China"],"affiliations":[{"raw_affiliation_string":"School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China","institution_ids":["https://openalex.org/I179026463"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002254171","display_name":"Suxia Xing","orcid":null},"institutions":[{"id":"https://openalex.org/I179026463","display_name":"Beijing Technology and Business University","ror":"https://ror.org/013e0zm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I179026463"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Suxia Xing","raw_affiliation_strings":["School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China"],"affiliations":[{"raw_affiliation_string":"School of Computer and Information Engineering, Beijing Technology and Business University, Beijing, China","institution_ids":["https://openalex.org/I179026463"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100450785"],"corresponding_institution_ids":["https://openalex.org/I179026463"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.21966374,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"33","issue":null,"first_page":"1201","last_page":"1206"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12647","display_name":"Traditional Chinese Medicine Studies","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.8849747180938721},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7631808519363403},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"Linear discriminant analysis","score":0.7171294689178467},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.6685840487480164},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.6394436359405518},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.629766583442688},{"id":"https://openalex.org/keywords/computer-aided-diagnosis","display_name":"Computer-aided diagnosis","score":0.4409283399581909},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3343013823032379},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.18109044432640076},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.17082372307777405}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.8849747180938721},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7631808519363403},{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.7171294689178467},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.6685840487480164},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.6394436359405518},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.629766583442688},{"id":"https://openalex.org/C2779549770","wikidata":"https://www.wikidata.org/wiki/Q1122413","display_name":"Computer-aided diagnosis","level":2,"score":0.4409283399581909},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3343013823032379},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18109044432640076},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.17082372307777405}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/icsai48974.2019.9010118","is_oa":false,"landing_page_url":"https://doi.org/10.1109/icsai48974.2019.9010118","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 6th International Conference on Systems and Informatics (ICSAI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6700000166893005,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W2054039029","https://openalex.org/W2088900896","https://openalex.org/W2090341258","https://openalex.org/W2099345876","https://openalex.org/W2141125852","https://openalex.org/W2143426320","https://openalex.org/W2153534417","https://openalex.org/W2155298532","https://openalex.org/W2379559262","https://openalex.org/W2777186991","https://openalex.org/W2944090748","https://openalex.org/W2947810057","https://openalex.org/W4211156109"],"related_works":["https://openalex.org/W4402452563","https://openalex.org/W2250488071","https://openalex.org/W2356150353","https://openalex.org/W2090763504","https://openalex.org/W2018643641","https://openalex.org/W2380744779","https://openalex.org/W2967867994","https://openalex.org/W2469878540","https://openalex.org/W1999647744","https://openalex.org/W148178222"],"abstract_inverted_index":{"With":[0],"the":[1,79,86,95,106,109,115,126,147,152,164],"vigorous":[2],"development":[3],"of":[4,22,50,90,130,177],"computer":[5],"and":[6,15,42,73,100,125,133,139,171,179],"pattern":[7],"recognition":[8],"technologies,":[9],"using":[10],"magnetic":[11],"resonance":[12],"imaging":[13],"(MRI)":[14],"machine":[16,123],"learning":[17],"methods":[18],"to":[19,84,104],"assist":[20,172],"diagnosis":[21,49,176],"Alzheimer's":[23],"disease":[24],"(AD)":[25],"has":[26],"became":[27],"a":[28],"research":[29],"hotspot.":[30],"A":[31],"new":[32],"method":[33,166],"based":[34],"on":[35,98,108,151],"Support":[36],"Vector":[37],"Machine-Recursive":[38],"Feature":[39],"Elimination":[40],"(SVM-RFE)":[41],"Linear":[43],"Discriminant":[44],"Analysis":[45],"(LDA)":[46],"for":[47,174],"aided":[48],"AD":[51,178],"is":[52,102],"proposed":[53,165],"in":[54],"this":[55],"study.":[56],"Firstly,":[57],"Structural":[58],"MRI":[59],"images":[60],"including":[61],"34":[62],"patients":[63],"with":[64,68,142],"AD,":[65],"26":[66],"subjects":[67],"subjective":[69],"memory":[70],"complaints":[71],"(SMC)":[72],"50":[74],"normal":[75],"controls":[76],"(NC)":[77],"from":[78],"ADNI":[80],"database":[81],"are":[82,118],"preprocessed":[83],"obtain":[85],"gray":[87,111],"matter":[88,112],"volumes":[89],"90":[91],"brain":[92],"regions.":[93],"Then":[94],"fusion":[96,153],"idea":[97,154],"SVM-RFE":[99,143],"LDA":[101,145],"used":[103],"select":[105],"characteristics":[107],"above":[110,159],"volumes.":[113],"Finally,":[114],"selected":[116],"features":[117,170],"classified":[119],"by":[120],"support":[121],"vector":[122],"(SVM),":[124],"average":[127,148],"classification":[128,149],"accuracies":[129],"AD/NC,":[131],"AD/SMC":[132],"NC/SMC":[134],"reach":[135],"respectively":[136],"94%,":[137],"100%":[138],"93.6%.":[140],"Compared":[141],"or":[144],"alone,":[146],"results":[150,161],"have":[155],"obvious":[156],"advantages.":[157],"The":[158],"experimental":[160],"show":[162],"that":[163],"can":[167],"effectively":[168],"extract":[169],"doctors":[173],"exact":[175],"SMC.":[180]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}