{"id":"https://openalex.org/W3194506913","doi":"https://doi.org/10.1109/icip42928.2021.9506695","title":"Super-Resolved Imaging of Early-Stage Dynamics in the Immune Response","display_name":"Super-Resolved Imaging of Early-Stage Dynamics in the Immune Response","publication_year":2021,"publication_date":"2021-08-23","ids":{"openalex":"https://openalex.org/W3194506913","doi":"https://doi.org/10.1109/icip42928.2021.9506695","mag":"3194506913"},"language":"en","primary_location":{"id":"doi:10.1109/icip42928.2021.9506695","is_oa":false,"landing_page_url":"https://doi.org/10.1109/icip42928.2021.9506695","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE International Conference on Image Processing (ICIP)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089140003","display_name":"Yair Ben Sahel","orcid":null},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Yair Ben Sahel","raw_affiliation_strings":["Weizmann Institute of Science,Department of Computer Science and Applied Mathematics,Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weizmann Institute of Science,Department of Computer Science and Applied Mathematics,Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078337390","display_name":"Gilli Dardikman-Yoffe","orcid":null},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Gilli Dardikman-Yoffe","raw_affiliation_strings":["Weizmann Institute of Science,Department of Computer Science and Applied Mathematics,Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weizmann Institute of Science,Department of Computer Science and Applied Mathematics,Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005913897","display_name":"Yonina C. Eldar","orcid":"https://orcid.org/0000-0003-4358-5304"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Yonina C. Eldar","raw_affiliation_strings":["Weizmann Institute of Science,Department of Computer Science and Applied Mathematics,Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weizmann Institute of Science,Department of Computer Science and Applied Mathematics,Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112678148","display_name":"Shirsendu Gosh","orcid":null},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Shirsendu Gosh","raw_affiliation_strings":["Weizmann Institute of Science,Department of Chemical Physics,Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weizmann Institute of Science,Department of Chemical Physics,Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003319572","display_name":"Gilad Haran","orcid":"https://orcid.org/0000-0003-1837-9779"},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Gilad Haran","raw_affiliation_strings":["Weizmann Institute of Science,Department of Chemical Physics,Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weizmann Institute of Science,Department of Chemical Physics,Israel","institution_ids":["https://openalex.org/I53964585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I53964585"],"apc_list":null,"apc_paid":null,"fwci":2.3485,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.88811189,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"3468","last_page":"3472"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stage","display_name":"Stage (stratigraphy)","score":0.591858446598053},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.5481921434402466},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.44058042764663696},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.36914515495300293},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.22325599193572998},{"id":"https://openalex.org/keywords/geology","display_name":"Geology","score":0.15791571140289307},{"id":"https://openalex.org/keywords/acoustics","display_name":"Acoustics","score":0.10596573352813721},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.09425663948059082}],"concepts":[{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.591858446598053},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.5481921434402466},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.44058042764663696},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.36914515495300293},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.22325599193572998},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.15791571140289307},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.10596573352813721},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09425663948059082},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/icip42928.2021.9506695","is_oa":false,"landing_page_url":"https://doi.org/10.1109/icip42928.2021.9506695","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE International Conference on Image Processing (ICIP)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6800000071525574,"display_name":"No poverty","id":"https://metadata.un.org/sdg/1"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320314070","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142"},{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1562441478","https://openalex.org/W1770500012","https://openalex.org/W1987415890","https://openalex.org/W1992858116","https://openalex.org/W2006235343","https://openalex.org/W2025748968","https://openalex.org/W2054455698","https://openalex.org/W2065681262","https://openalex.org/W2096234619","https://openalex.org/W2100543212","https://openalex.org/W2115706991","https://openalex.org/W2126873850","https://openalex.org/W2132053231","https://openalex.org/W2138197182","https://openalex.org/W2165784749","https://openalex.org/W2271221198","https://openalex.org/W2522267165","https://openalex.org/W2613004608","https://openalex.org/W2810682944","https://openalex.org/W2963709974","https://openalex.org/W3010883635","https://openalex.org/W4300263211"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052","https://openalex.org/W4402327032","https://openalex.org/W2382290278"],"abstract_inverted_index":{"The":[0],"use":[1,136],"of":[2,10,42,50,56,94,103,137],"photo-activated":[3],"fluorescent":[4],"molecules":[5],"to":[6,18,66,70,91,111,127],"create":[7],"long":[8],"sequences":[9],"low-density,":[11],"diffraction-limited":[12],"images":[13],"gives":[14],"us":[15],"the":[16,54,59,72,95,100,122,128,135,146],"ability":[17],"achieve":[19,112],"highly-precise":[20],"molecule":[21],"localizations.":[22],"However,":[23],"this":[24,79],"methodology":[25],"requires":[26],"lengthy":[27],"imaging":[28,93,114,140],"times,":[29],"resulting":[30],"in":[31,62,68],"poor":[32],"temporal":[33],"resolution.":[34],"This":[35],"is":[36],"particularly":[37],"problematic":[38],"when":[39],"dynamic":[40,141],"interactions":[41],"live":[43],"cells":[44],"on":[45],"short":[46],"time":[47],"scales":[48],"are":[49,109],"interest.":[51],"We":[52],"consider":[53],"problem":[55],"shortening":[57],"dramatically":[58],"acquisition":[60],"times":[61],"super-resolution":[63,88],"microscopy":[64],"down":[65],"seconds,":[67],"order":[69],"image":[71],"cellular":[73,142],"dynamics":[74],"during":[75,121],"T-cell":[76,118],"activation.":[77],"For":[78],"purpose,":[80],"we":[81,108],"apply":[82],"our":[83,132],"newly":[84],"developed":[85],"method":[86],"for":[87,106,139],"microscopy,":[89],"SPARCOM,":[90],"real-time":[92],"immune":[96],"response":[97],"initiation.":[98],"Despite":[99],"small":[101],"number":[102],"frames":[104],"used":[105],"reconstruction,":[107],"able":[110],"high-quality":[113],"that":[115],"shows":[116],"how":[117],"receptors":[119],"re-organize":[120],"activation":[123],"events,":[124],"with":[125],"respect":[126],"cell\u2019s":[129],"surface.":[130],"Thus,":[131],"work":[133],"demonstrates":[134],"SPARCOM":[138],"processes":[143],"well":[144],"below":[145],"diffraction":[147],"limit.":[148]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}