{"id":"https://openalex.org/W2005892737","doi":"https://doi.org/10.1109/icip.2011.6115749","title":"Automated nuclei clump decomposition for image analysis in neuronal cell fluorescent microscopy","display_name":"Automated nuclei clump decomposition for image analysis in neuronal cell fluorescent microscopy","publication_year":2011,"publication_date":"2011-09-01","ids":{"openalex":"https://openalex.org/W2005892737","doi":"https://doi.org/10.1109/icip.2011.6115749","mag":"2005892737"},"language":"en","primary_location":{"id":"doi:10.1109/icip.2011.6115749","is_oa":false,"landing_page_url":"https://doi.org/10.1109/icip.2011.6115749","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 18th IEEE International Conference on Image Processing","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101760811","display_name":"Wei Xiong","orcid":"https://orcid.org/0000-0002-1399-5559"},"institutions":[{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Wei Xiong","raw_affiliation_strings":["Institute for Infocomm Research, Singapore","Institute for Infocomm Research, 1 Fusionopolis Way, #21-01 Connexis, South Tower, Singapore 138632"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research, Singapore","institution_ids":["https://openalex.org/I3005327000"]},{"raw_affiliation_string":"Institute for Infocomm Research, 1 Fusionopolis Way, #21-01 Connexis, South Tower, Singapore 138632","institution_ids":["https://openalex.org/I3005327000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113457497","display_name":"Shue-Ching Chia","orcid":null},"institutions":[{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Shue-Ching Chia","raw_affiliation_strings":["Institute for Infocomm Research, Singapore","Institute for Infocomm Research, 1 Fusionopolis Way, #21-01 Connexis, South Tower, Singapore 138632"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research, Singapore","institution_ids":["https://openalex.org/I3005327000"]},{"raw_affiliation_string":"Institute for Infocomm Research, 1 Fusionopolis Way, #21-01 Connexis, South Tower, Singapore 138632","institution_ids":["https://openalex.org/I3005327000"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077258552","display_name":"Joo\u2010Hwee Lim","orcid":"https://orcid.org/0000-0002-4103-3824"},"institutions":[{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Joo Hwee Lim","raw_affiliation_strings":["Institute for Infocomm Research, Singapore","Institute for Infocomm Research, 1 Fusionopolis Way, #21-01 Connexis, South Tower, Singapore 138632"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research, Singapore","institution_ids":["https://openalex.org/I3005327000"]},{"raw_affiliation_string":"Institute for Infocomm Research, 1 Fusionopolis Way, #21-01 Connexis, South Tower, Singapore 138632","institution_ids":["https://openalex.org/I3005327000"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I3005327000"],"apc_list":null,"apc_paid":null,"fwci":2.8732,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.89267167,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"smc 9","issue":null,"first_page":"1577","last_page":"1580"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.8506829738616943},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6492242813110352},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5941493511199951},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5768206119537354},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.5188985466957092},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.5091649889945984},{"id":"https://openalex.org/keywords/decomposition","display_name":"Decomposition","score":0.49892187118530273},{"id":"https://openalex.org/keywords/matching","display_name":"Matching (statistics)","score":0.46858447790145874},{"id":"https://openalex.org/keywords/fluorescence-microscope","display_name":"Fluorescence microscope","score":0.4360731840133667},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.4137519299983978},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4107438325881958},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.3611149787902832},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17181316018104553},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.14045032858848572},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.12911301851272583},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.12507811188697815}],"concepts":[{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.8506829738616943},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6492242813110352},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5941493511199951},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5768206119537354},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.5188985466957092},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.5091649889945984},{"id":"https://openalex.org/C124681953","wikidata":"https://www.wikidata.org/wiki/Q339062","display_name":"Decomposition","level":2,"score":0.49892187118530273},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.46858447790145874},{"id":"https://openalex.org/C169274487","wikidata":"https://www.wikidata.org/wiki/Q840211","display_name":"Fluorescence microscope","level":3,"score":0.4360731840133667},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.4137519299983978},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4107438325881958},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.3611149787902832},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17181316018104553},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.14045032858848572},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12911301851272583},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12507811188697815},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/icip.2011.6115749","is_oa":false,"landing_page_url":"https://doi.org/10.1109/icip.2011.6115749","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 18th IEEE International Conference on Image Processing","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1545467875","https://openalex.org/W1637405421","https://openalex.org/W1829584193","https://openalex.org/W1983823085","https://openalex.org/W2004686460","https://openalex.org/W2013985817","https://openalex.org/W2019637351","https://openalex.org/W2032322171","https://openalex.org/W2035060798","https://openalex.org/W2035744969","https://openalex.org/W2077181969","https://openalex.org/W2077191558","https://openalex.org/W2093677713","https://openalex.org/W2124032926","https://openalex.org/W2124260943","https://openalex.org/W2133059825","https://openalex.org/W2167435976","https://openalex.org/W2766378918","https://openalex.org/W4300569535","https://openalex.org/W6844399076"],"related_works":["https://openalex.org/W4211107619","https://openalex.org/W2161433272","https://openalex.org/W2894139091","https://openalex.org/W1637909","https://openalex.org/W1983780159","https://openalex.org/W659245948","https://openalex.org/W2793462084","https://openalex.org/W2094643072","https://openalex.org/W2087957833","https://openalex.org/W4206210906"],"abstract_inverted_index":{"Automated":[0],"clump":[1],"decomposition":[2],"is":[3],"crucial":[4],"for":[5],"the":[6,33,99,108],"analysis":[7,109],"of":[8,28,68,89,110],"neuronal":[9],"cell":[10,19],"fluorescent":[11],"microscopic":[12],"images":[13,112],"due":[14],"to":[15,41,60,97],"inevitable":[16],"nuclei":[17,44,57,116],"and":[18,30,53,56,63],"clumping.":[20],"Existing":[21],"techniques":[22],"are":[23],"not":[24],"satisfactory":[25],"in":[26,74,92,107],"terms":[27],"accuracy":[29,119],"efficiency.":[31],"In":[32],"current":[34],"work,":[35],"we":[36],"propose":[37],"a":[38,87],"new":[39],"method":[40],"automatically":[42],"decompose":[43],"clumps,":[45],"using":[46],"multiple":[47],"visual":[48],"cues":[49],"from":[50],"seeds,":[51],"skeletons,":[52],"object":[54],"boundaries":[55],"shape":[58,69,95],"models":[59,70],"deliver":[61],"robust":[62],"efficient":[64],"analysis.":[65],"The":[66],"use":[67],"enhances":[71],"its":[72],"robustness":[73],"handling":[75],"complicated":[76],"clumps":[77],"against":[78],"those":[79],"bottom-up":[80],"approaches":[81],"without":[82],"prior":[83],"knowledge.":[84],"We":[85],"adopt":[86],"strategy":[88],"model":[90],"verification":[91],"allowable":[93],"local":[94],"changes":[96],"improve":[98],"computational":[100],"efficiency":[101],"over":[102,114,121],"template":[103],"matching.":[104],"Validation":[105],"experiments":[106],"50":[111],"containing":[113],"2000":[115],"have":[117],"demonstrated":[118],"improvements":[120],"existing":[122],"techniques.":[123]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}