{"id":"https://openalex.org/W3200565236","doi":"https://doi.org/10.1109/iccsce52189.2021.9530885","title":"Fundamental Study of Cannabidiol Effect on MCF-7 with Low Voltage Pulse Electric Field","display_name":"Fundamental Study of Cannabidiol Effect on MCF-7 with Low Voltage Pulse Electric Field","publication_year":2021,"publication_date":"2021-08-27","ids":{"openalex":"https://openalex.org/W3200565236","doi":"https://doi.org/10.1109/iccsce52189.2021.9530885","mag":"3200565236"},"language":"en","primary_location":{"id":"doi:10.1109/iccsce52189.2021.9530885","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iccsce52189.2021.9530885","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 11th IEEE International Conference on Control System, Computing and Engineering (ICCSCE)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102347211","display_name":"Nur Adilah Abd Rahman","orcid":null},"institutions":[{"id":"https://openalex.org/I930072361","display_name":"Tun Hussein Onn University of Malaysia","ror":"https://ror.org/01c5wha71","country_code":"MY","type":"education","lineage":["https://openalex.org/I930072361"]}],"countries":["MY"],"is_corresponding":true,"raw_author_name":"Nur Adilah Abd Rahman","raw_affiliation_strings":["Biomedical Modelling and Simulation Research Group, Faculty of Electrical and Electronics Engineering, Universiti Tun Hussein Onn Malaysia, Batu Pahat, Johor, Malaysia"],"affiliations":[{"raw_affiliation_string":"Biomedical Modelling and Simulation Research Group, Faculty of Electrical and Electronics Engineering, Universiti Tun Hussein Onn Malaysia, Batu Pahat, Johor, Malaysia","institution_ids":["https://openalex.org/I930072361"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069661362","display_name":"Muhammad Mahadi Abdul Jamil","orcid":"https://orcid.org/0000-0003-2559-3909"},"institutions":[{"id":"https://openalex.org/I930072361","display_name":"Tun Hussein Onn University of Malaysia","ror":"https://ror.org/01c5wha71","country_code":"MY","type":"education","lineage":["https://openalex.org/I930072361"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Muhammad Mahadi Abdul Jamil","raw_affiliation_strings":["Biomedical Modelling and Simulation Research Group, Faculty of Electrical and Electronics Engineering, Universiti Tun Hussein Onn Malaysia, Batu Pahat, Johor, Malaysia"],"affiliations":[{"raw_affiliation_string":"Biomedical Modelling and Simulation Research Group, Faculty of Electrical and Electronics Engineering, Universiti Tun Hussein Onn Malaysia, Batu Pahat, Johor, Malaysia","institution_ids":["https://openalex.org/I930072361"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006546865","display_name":"Mohamad Nazib Adon","orcid":"https://orcid.org/0000-0001-8676-9862"},"institutions":[{"id":"https://openalex.org/I930072361","display_name":"Tun Hussein Onn University of Malaysia","ror":"https://ror.org/01c5wha71","country_code":"MY","type":"education","lineage":["https://openalex.org/I930072361"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Mohamad Nazib Adon","raw_affiliation_strings":["Biomedical Modelling and Simulation Research Group, Faculty of Electrical and Electronics Engineering, Universiti Tun Hussein Onn Malaysia, Batu Pahat, Johor, Malaysia"],"affiliations":[{"raw_affiliation_string":"Biomedical Modelling and Simulation Research Group, Faculty of Electrical and Electronics Engineering, Universiti Tun Hussein Onn Malaysia, Batu Pahat, Johor, Malaysia","institution_ids":["https://openalex.org/I930072361"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030878461","display_name":"Ahmad Basri Zainal","orcid":null},"institutions":[{"id":"https://openalex.org/I4528857","display_name":"University of Kuala Lumpur","ror":"https://ror.org/026wwrx19","country_code":"MY","type":"education","lineage":["https://openalex.org/I4528857"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Ahmad Basri Zainal","raw_affiliation_strings":["Electronics Section, Universiti Kuala Lumpur British Malaysian Institute, Gombak, Selangor, Malaysia"],"affiliations":[{"raw_affiliation_string":"Electronics Section, Universiti Kuala Lumpur British Malaysian Institute, Gombak, Selangor, Malaysia","institution_ids":["https://openalex.org/I4528857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033408989","display_name":"Farideh Javid","orcid":"https://orcid.org/0000-0002-2775-6276"},"institutions":[{"id":"https://openalex.org/I133837150","display_name":"University of Huddersfield","ror":"https://ror.org/05t1h8f27","country_code":"GB","type":"education","lineage":["https://openalex.org/I133837150"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Farideh Javid","raw_affiliation_strings":["School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, UK"],"affiliations":[{"raw_affiliation_string":"School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, UK","institution_ids":["https://openalex.org/I133837150"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018556285","display_name":"Mansour Youseffi","orcid":"https://orcid.org/0000-0002-4639-1313"},"institutions":[{"id":"https://openalex.org/I139894009","display_name":"University of Bradford","ror":"https://ror.org/00vs8d940","country_code":"GB","type":"education","lineage":["https://openalex.org/I139894009"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mansour Youseffi","raw_affiliation_strings":["Biomedical and Electronics Engineering Department, Faculty of Engineering and Informatics, University of Bradford, Bradford, West Yorkshire, UK"],"affiliations":[{"raw_affiliation_string":"Biomedical and Electronics Engineering Department, Faculty of Engineering and Informatics, University of Bradford, Bradford, West Yorkshire, UK","institution_ids":["https://openalex.org/I139894009"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5102347211"],"corresponding_institution_ids":["https://openalex.org/I930072361"],"apc_list":null,"apc_paid":null,"fwci":0.1427,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.52129688,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"3","issue":null,"first_page":"13","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.9914000034332275,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.9883999824523926,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.7591415047645569},{"id":"https://openalex.org/keywords/cancer-cell","display_name":"Cancer cell","score":0.683715283870697},{"id":"https://openalex.org/keywords/mcf-7","display_name":"MCF-7","score":0.6623247861862183},{"id":"https://openalex.org/keywords/cannabidiol","display_name":"Cannabidiol","score":0.6605552434921265},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.5943912267684937},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"Colorectal cancer","score":0.5675181150436401},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.5245004892349243},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"Lung cancer","score":0.5049129128456116},{"id":"https://openalex.org/keywords/viability-assay","display_name":"Viability assay","score":0.49130144715309143},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"Prostate cancer","score":0.48683661222457886},{"id":"https://openalex.org/keywords/apoptosis","display_name":"Apoptosis","score":0.48071911931037903},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.38788098096847534},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.37401580810546875},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.3609333038330078},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.2990504503250122},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.26134252548217773},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.21667087078094482},{"id":"https://openalex.org/keywords/human-breast","display_name":"Human breast","score":0.09835085272789001}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.7591415047645569},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.683715283870697},{"id":"https://openalex.org/C109541995","wikidata":"https://www.wikidata.org/wiki/Q1881253","display_name":"MCF-7","level":5,"score":0.6623247861862183},{"id":"https://openalex.org/C2776895053","wikidata":"https://www.wikidata.org/wiki/Q422917","display_name":"Cannabidiol","level":3,"score":0.6605552434921265},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5943912267684937},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5675181150436401},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5245004892349243},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5049129128456116},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.49130144715309143},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.48683661222457886},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.48071911931037903},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38788098096847534},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37401580810546875},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3609333038330078},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.2990504503250122},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26134252548217773},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21667087078094482},{"id":"https://openalex.org/C2994423619","wikidata":"https://www.wikidata.org/wiki/Q9103","display_name":"Human breast","level":4,"score":0.09835085272789001},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C2777056318","wikidata":"https://www.wikidata.org/wiki/Q79817","display_name":"Cannabis","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/iccsce52189.2021.9530885","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iccsce52189.2021.9530885","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 11th IEEE International Conference on Control System, Computing and Engineering (ICCSCE)","raw_type":"proceedings-article"},{"id":"pmh:oai:pure.atira.dk:publications/d0bef072-078a-46fb-be3b-e8a193cea2d2","is_oa":false,"landing_page_url":"http://www.scopus.com/inward/record.url?scp=85116294728&partnerID=8YFLogxK","pdf_url":null,"source":{"id":"https://openalex.org/S4306402508","display_name":"Huddersfield Research Portal (University of Huddersfield)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I133837150","host_organization_name":"University of Huddersfield","host_organization_lineage":["https://openalex.org/I133837150"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Rahman, N A A, Jamil, M M A, Adon, M N, Zainal, A B, Javid, F & Youseffi, M 2021, Fundamental Study of Cannabidiol Effect on MCF-7 with Low Voltage Pulse Electric Field. in Proceedings - 2021 11th IEEE International Conference on Control System, Computing and Engineering, ICCSCE 2021. Institute of Electrical and Electronics Engineers Inc., pp. 13-18, 11th IEEE International Conference on Control System, Computing and Engineering, Penang, Malaysia, 27/08/21. https://doi.org/10.1109/ICCSCE52189.2021.9530885","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8600000143051147,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1434138403","https://openalex.org/W1520294963","https://openalex.org/W1901609230","https://openalex.org/W1967093606","https://openalex.org/W1979368453","https://openalex.org/W1990399859","https://openalex.org/W2039338526","https://openalex.org/W2106963052","https://openalex.org/W2109890960","https://openalex.org/W2140287290","https://openalex.org/W2162071711","https://openalex.org/W2264716732","https://openalex.org/W2305988154","https://openalex.org/W2319910816","https://openalex.org/W2327510390","https://openalex.org/W2519838534","https://openalex.org/W2728645505","https://openalex.org/W2738408982","https://openalex.org/W2741779248","https://openalex.org/W2773535565","https://openalex.org/W2778289014","https://openalex.org/W2785437298","https://openalex.org/W2792848996","https://openalex.org/W2796360404","https://openalex.org/W2800520019","https://openalex.org/W2809568190","https://openalex.org/W2809739952","https://openalex.org/W2885020841","https://openalex.org/W2888448931","https://openalex.org/W2888796235","https://openalex.org/W2901575037","https://openalex.org/W2911921345","https://openalex.org/W2915455779","https://openalex.org/W2940719270","https://openalex.org/W2974783557","https://openalex.org/W2981031629","https://openalex.org/W3095818160","https://openalex.org/W3126281851","https://openalex.org/W4285719527","https://openalex.org/W6747403493","https://openalex.org/W6747956211"],"related_works":["https://openalex.org/W1997976267","https://openalex.org/W2924580846","https://openalex.org/W2381753167","https://openalex.org/W2513729362","https://openalex.org/W2501960686","https://openalex.org/W3205513528","https://openalex.org/W2368058280","https://openalex.org/W2062020701","https://openalex.org/W2962756305","https://openalex.org/W3200565236"],"abstract_inverted_index":{"In":[0],"various":[1],"cancer":[2,39,45,71,110,125,144,167,191,202,207],"types,":[3,73],"plant":[4],"extract":[5],"has":[6,27,102],"been":[7,29,104],"found":[8],"to":[9,90,200],"be":[10,121,170,181,196],"an":[11,197],"important":[12],"and":[13,41,81,136,188],"useful":[14],"preventive":[15],"agent":[16],"for":[17,143,165,172],"chemotherapy.":[18],"Cannabidiol":[19,157],"is":[20,154],"one":[21,107],"of":[22,38,44,54,67,94,108,117,177],"the":[23,42,51,65,92,97,124],"interesting":[24],"plants":[25],"that":[26,62],"recently":[28],"identified":[30],"as":[31,75,106],"a":[32],"possible":[33],"anti-cancer":[34],"agent.":[35],"The":[36,84,146,175],"inhibition":[37],"cells":[40,68,168],"activation":[43],"cell":[46,72,98,185],"death":[47],"or":[48,205],"apoptosis":[49],"are":[50],"major":[52],"effects":[53,142],"cannabinoids":[55],"on":[56,96],"tumours.":[57],"Latest":[58],"studies":[59],"have":[60],"shown":[61],"cannabidiol":[63],"decreases":[64],"viability":[66],"in":[69,113,133],"multiple":[70],"such":[74],"leukemia,":[76],"colorectal,":[77],"breast":[78,166],"cancer,":[79],"lung,":[80],"prostate":[82],"cancer.":[83],"pulse":[85,147],"electric":[86,148],"fields":[87],"were":[88],"known":[89],"affect":[91],"opening":[93],"pores":[95],"membrane":[99],"effectively.":[100],"It":[101],"also":[103],"used":[105,153],"today\u2019s":[109],"treatment":[111,126],"techniques":[112],"clinical":[114],"practice.":[115],"Both":[116],"these":[118],"approaches":[119,194],"can":[120,180],"combined.":[122],"For":[123],"procedure,":[127],"it":[128],"could":[129,195],"increase":[130],"further":[131],"reduction":[132],"time":[134],"taken":[135],"less":[137],"harmful":[138],"/":[139],"after":[140],"side":[141,211],"patients.":[145],"field":[149],"range":[150],"most":[151],"widely":[152],"100-1000":[155],"V/cm.":[156],"inhibitory":[158],"concentration":[159],"(IC":[160],"<inf":[161],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[162],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">50</inf>":[163],")":[164],"will":[169],"estimated":[171],"this":[173,178],"study.":[174],"efficacy":[176],"mechanism":[179],"determined":[182],"by":[183,190],"controlling":[184],"proliferation,":[186],"viability,":[187],"anti-proliferation":[189],"cells.":[192],"These":[193],"effective":[198],"way":[199],"treat":[201],"without":[203],"affecting":[204],"leaving":[206],"patients":[208],"with":[209],"any":[210],"effects.":[212]},"counts_by_year":[{"year":2023,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}