{"id":"https://openalex.org/W3178685243","doi":"https://doi.org/10.1109/iccp51581.2021.9466256","title":"Real-Time Light Field 3D Microscopy via Sparsity-Driven Learned Deconvolution","display_name":"Real-Time Light Field 3D Microscopy via Sparsity-Driven Learned Deconvolution","publication_year":2021,"publication_date":"2021-05-23","ids":{"openalex":"https://openalex.org/W3178685243","doi":"https://doi.org/10.1109/iccp51581.2021.9466256","mag":"3178685243"},"language":"en","primary_location":{"id":"doi:10.1109/iccp51581.2021.9466256","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iccp51581.2021.9466256","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE International Conference on Computational Photography (ICCP)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007707727","display_name":"Josu\u00e9 Page Vizca\u00edno","orcid":"https://orcid.org/0000-0002-5848-3063"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Josue Page Vizcaino","raw_affiliation_strings":["Computational Imaging and Inverse Problems Group, Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Imaging and Inverse Problems Group, Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079926117","display_name":"Zeguan Wang","orcid":"https://orcid.org/0000-0001-9149-3389"},"institutions":[{"id":"https://openalex.org/I4210146958","display_name":"Synthetic Biologics (United States)","ror":"https://ror.org/04trz4q34","country_code":"US","type":"company","lineage":["https://openalex.org/I4210146958"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zeguan Wang","raw_affiliation_strings":["Synthetic Neurobiology Group, Massachusetts Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Synthetic Neurobiology Group, Massachusetts Institute of Technology","institution_ids":["https://openalex.org/I4210146958","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036799670","display_name":"Panagiotis Symvoulidis","orcid":"https://orcid.org/0000-0002-1396-3426"},"institutions":[{"id":"https://openalex.org/I4210146958","display_name":"Synthetic Biologics (United States)","ror":"https://ror.org/04trz4q34","country_code":"US","type":"company","lineage":["https://openalex.org/I4210146958"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Panagiotis Symvoulidis","raw_affiliation_strings":["Synthetic Neurobiology Group, Massachusetts Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Synthetic Neurobiology Group, Massachusetts Institute of Technology","institution_ids":["https://openalex.org/I4210146958","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070940574","display_name":"Paolo Favaro","orcid":"https://orcid.org/0000-0003-3546-8247"},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Paolo Favaro","raw_affiliation_strings":["Computer Vision Group, University of Bern"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Vision Group, University of Bern","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037325408","display_name":"Burcu Guner\u2010Ataman","orcid":null},"institutions":[{"id":"https://openalex.org/I144112489","display_name":"McGovern Institute for Brain Research","ror":"https://ror.org/05ymca674","country_code":"US","type":"facility","lineage":["https://openalex.org/I144112489","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Burcu Guner-Ataman","raw_affiliation_strings":["McGovern Institute for Brain Research, Massachusetts Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McGovern Institute for Brain Research, Massachusetts Institute of Technology","institution_ids":["https://openalex.org/I144112489","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109593948","display_name":"Edward S. Boyden","orcid":null},"institutions":[{"id":"https://openalex.org/I4210146958","display_name":"Synthetic Biologics (United States)","ror":"https://ror.org/04trz4q34","country_code":"US","type":"company","lineage":["https://openalex.org/I4210146958"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward S. Boyden","raw_affiliation_strings":["Synthetic Neurobiology Group, Massachusetts Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Synthetic Neurobiology Group, Massachusetts Institute of Technology","institution_ids":["https://openalex.org/I4210146958","https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021375348","display_name":"Tobias Lasser","orcid":"https://orcid.org/0000-0001-5669-920X"},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tobias Lasser","raw_affiliation_strings":["Computational Imaging and Inverse Problems Group, Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Imaging and Inverse Problems Group, Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":9.3981,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.97743149,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11897","display_name":"Digital Holography and Microscopy","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6944372653961182},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.669748842716217},{"id":"https://openalex.org/keywords/iterative-reconstruction","display_name":"Iterative reconstruction","score":0.551092267036438},{"id":"https://openalex.org/keywords/deconvolution","display_name":"Deconvolution","score":0.550037145614624},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5491979718208313},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.524470329284668},{"id":"https://openalex.org/keywords/voxel","display_name":"Voxel","score":0.43101271986961365},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3776184320449829},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.2707488536834717}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6944372653961182},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.669748842716217},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.551092267036438},{"id":"https://openalex.org/C174576160","wikidata":"https://www.wikidata.org/wiki/Q1183700","display_name":"Deconvolution","level":2,"score":0.550037145614624},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5491979718208313},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.524470329284668},{"id":"https://openalex.org/C54170458","wikidata":"https://www.wikidata.org/wiki/Q663554","display_name":"Voxel","level":2,"score":0.43101271986961365},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3776184320449829},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2707488536834717}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/iccp51581.2021.9466256","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iccp51581.2021.9466256","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE International Conference on Computational Photography (ICCP)","raw_type":"proceedings-article"},{"id":"pmh:doi:10.48350/168310","is_oa":false,"landing_page_url":"https://boris-portal.unibe.ch/handle/20.500.12422/69516","pdf_url":null,"source":{"id":"https://openalex.org/S4406922384","display_name":"Open MIND","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"ConferencePaper"},{"id":"pmh:oai:boris.unibe.ch:168310","is_oa":false,"landing_page_url":"https://boris.unibe.ch/168310/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401747","display_name":"BORIS (University Library Bern)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210103840","host_organization_name":"Nakuru County Council","host_organization_lineage":["https://openalex.org/I4210103840"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Vizcaino, Josue Page; Wang, Zeguan; Symvoulidis, Panagiotis; Favaro, Paolo; Guner-Ataman, Burcu; Boyden, Edward S.; Lasser, Tobias (May 2021). Real-Time Light Field 3D Microscopy via Sparsity-Driven Learned Deconvolution. IEEE Xplore, pp. 1-11. IEEE 10.1109/ICCP51581.2021.9466256 <http://dx.doi.org/10.1109/ICCP51581.2021.9466256>","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1994751817","display_name":null,"funder_award_id":"LA 3264/2-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1677182931","https://openalex.org/W1736339626","https://openalex.org/W1901129140","https://openalex.org/W1994574914","https://openalex.org/W2060167709","https://openalex.org/W2108980608","https://openalex.org/W2132537080","https://openalex.org/W2386621445","https://openalex.org/W2611648074","https://openalex.org/W2661720377","https://openalex.org/W2754636875","https://openalex.org/W2781310020","https://openalex.org/W2800089816","https://openalex.org/W2836171385","https://openalex.org/W2898972076","https://openalex.org/W2950291885","https://openalex.org/W2950754606","https://openalex.org/W2966800242","https://openalex.org/W2974670148","https://openalex.org/W2981517676","https://openalex.org/W2981963355","https://openalex.org/W2989882321","https://openalex.org/W2998660946","https://openalex.org/W3000696985","https://openalex.org/W3003875370","https://openalex.org/W3013429942","https://openalex.org/W3023104235","https://openalex.org/W3037807978","https://openalex.org/W3046588250","https://openalex.org/W3082328657","https://openalex.org/W3084022149","https://openalex.org/W3101842671","https://openalex.org/W3122841120","https://openalex.org/W3158688284","https://openalex.org/W4211065609","https://openalex.org/W4285719527","https://openalex.org/W6639824700","https://openalex.org/W6737286391","https://openalex.org/W6767372615","https://openalex.org/W6772738524","https://openalex.org/W6781609350","https://openalex.org/W6782776644"],"related_works":["https://openalex.org/W4250106855","https://openalex.org/W2037261263","https://openalex.org/W3149087629","https://openalex.org/W4231036715","https://openalex.org/W2032074591","https://openalex.org/W3027020613","https://openalex.org/W1986156575","https://openalex.org/W3193619106","https://openalex.org/W2751689993","https://openalex.org/W2053307699"],"abstract_inverted_index":{"Light":[0],"Field":[1],"Microscopy":[2],"(LFM)":[3],"is":[4,57,144],"a":[5,27,45,94,115,118,128,134,194],"scan-less":[6],"3D":[7,28,95,139,169],"imaging":[8,56,181,186,208],"technique":[9],"capable":[10],"of":[11,41,53,104,117,127,172,176,188],"capturing":[12],"fast":[13],"biological":[14],"processes,":[15],"such":[16,156],"as":[17,157],"neural":[18,62,119,135,158,174],"activity":[19,175],"in":[20,44,108],"zebrafish.":[21],"However,":[22],"current":[23,77],"methods":[24,80],"to":[25,58,71,92,146,152],"recover":[26],"volume":[29],"from":[30],"the":[31,39,42,50,64,73,100,124,173],"raw":[32],"data":[33,149],"require":[34],"long":[35],"reconstruction":[36,67,96],"times":[37],"hampering":[38],"usability":[40],"microscope":[43],"closed-loop":[46],"system.":[47],"Moreover,":[48],"because":[49],"main":[51],"focus":[52],"zebrafish":[54],"brain":[55],"isolate":[59],"and":[60,84,133,151,202],"study":[61],"activity,":[63],"ideal":[65],"volumetric":[66,170],"should":[68],"be":[69],"sparse":[70,78,102,125,168],"reveal":[72],"dominant":[74],"signals.":[75],"Unfortunately,":[76],"decomposition":[79],"are":[81],"computationally":[82],"intensive":[83],"thus":[85],"introduce":[86,93],"substantial":[87],"delays.":[88],"This":[89],"motivates":[90],"us":[91],"method":[97],"that":[98,122],"recovers":[99,123],"spatio-temporally":[101],"components":[103,126],"an":[105,180,185],"image":[106,131],"sequence":[107,132],"real-time.":[109],"In":[110,141],"this":[111],"work":[112,201],"we":[113],"propose":[114],"combination":[116],"network":[120,136],"(SLNet)":[121],"light":[129],"field":[130],"(XLFMNet)":[137],"for":[138],"reconstruction.":[140],"particular,":[142],"XLFMNet":[143],"able":[145],"achieve":[147],"high":[148],"fidelity":[150],"preserve":[153],"important":[154],"signals,":[155],"potentials,":[159],"even":[160],"on":[161],"previously":[162],"unobserved":[163],"samples.":[164],"We":[165],"demonstrate":[166],"successful":[167],"reconstructions":[171,205],"live":[177],"zebrafish,":[178],"with":[179],"span":[182],"covering":[183],"800\u00d7800\u00d7250Mm3at":[184],"rate":[187],"24":[189],"-":[190],"88Hz,":[191],"which":[192],"provides":[193],"1500":[195],"fold":[196],"speed":[197],"increase":[198],"against":[199],"prior":[200],"enables":[203],"real-time":[204],"without":[206],"sacrificing":[207],"resolution.":[209]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}