{"id":"https://openalex.org/W4312387329","doi":"https://doi.org/10.1109/icccnt54827.2022.9984600","title":"Comparative Study of Cancer Classification by Analysis of RNA-seq Gene Expression Levels","display_name":"Comparative Study of Cancer Classification by Analysis of RNA-seq Gene Expression Levels","publication_year":2022,"publication_date":"2022-10-03","ids":{"openalex":"https://openalex.org/W4312387329","doi":"https://doi.org/10.1109/icccnt54827.2022.9984600"},"language":"en","primary_location":{"id":"doi:10.1109/icccnt54827.2022.9984600","is_oa":false,"landing_page_url":"https://doi.org/10.1109/icccnt54827.2022.9984600","pdf_url":null,"source":{"id":"https://openalex.org/S4363607876","display_name":"2022 13th International Conference on Computing Communication and Networking Technologies (ICCCNT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 13th International Conference on Computing Communication and Networking Technologies (ICCCNT)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025283124","display_name":"A Amruth","orcid":null},"institutions":[{"id":"https://openalex.org/I81556334","display_name":"Amrita Vishwa Vidyapeetham","ror":"https://ror.org/03am10p12","country_code":"IN","type":"education","lineage":["https://openalex.org/I81556334"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Amruth A","raw_affiliation_strings":["Amrita School of Computing,Dept. of Computer Science and Engineering","Dept. of Computer Science and Engineering, Amrita School of Computing"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amrita School of Computing,Dept. of Computer Science and Engineering","institution_ids":["https://openalex.org/I81556334"]},{"raw_affiliation_string":"Dept. of Computer Science and Engineering, Amrita School of Computing","institution_ids":["https://openalex.org/I81556334"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041940320","display_name":"R Ramanan","orcid":null},"institutions":[{"id":"https://openalex.org/I81556334","display_name":"Amrita Vishwa Vidyapeetham","ror":"https://ror.org/03am10p12","country_code":"IN","type":"education","lineage":["https://openalex.org/I81556334"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ramanan R","raw_affiliation_strings":["Amrita School of Computing,Dept. of Computer Science and Engineering","Dept. of Computer Science and Engineering, Amrita School of Computing"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amrita School of Computing,Dept. of Computer Science and Engineering","institution_ids":["https://openalex.org/I81556334"]},{"raw_affiliation_string":"Dept. of Computer Science and Engineering, Amrita School of Computing","institution_ids":["https://openalex.org/I81556334"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108480113","display_name":"Rhea Paul","orcid":null},"institutions":[{"id":"https://openalex.org/I81556334","display_name":"Amrita Vishwa Vidyapeetham","ror":"https://ror.org/03am10p12","country_code":"IN","type":"education","lineage":["https://openalex.org/I81556334"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rhea Paul","raw_affiliation_strings":["Amrita School of Computing,Dept. of Computer Science and Engineering","Dept. of Computer Science and Engineering, Amrita School of Computing"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amrita School of Computing,Dept. of Computer Science and Engineering","institution_ids":["https://openalex.org/I81556334"]},{"raw_affiliation_string":"Dept. of Computer Science and Engineering, Amrita School of Computing","institution_ids":["https://openalex.org/I81556334"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061698010","display_name":"Sarada Jayan","orcid":"https://orcid.org/0000-0002-3756-4139"},"institutions":[{"id":"https://openalex.org/I81556334","display_name":"Amrita Vishwa Vidyapeetham","ror":"https://ror.org/03am10p12","country_code":"IN","type":"education","lineage":["https://openalex.org/I81556334"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sarada Jayan","raw_affiliation_strings":["Amrita School of Engineering, Bengaluru, Amrita Vishwa Vidyapeetham,Dept. of Mathematics,India","Dept. of Mathematics, Amrita School of Engineering, Bengaluru, Amrita Vishwa Vidyapeetham, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amrita School of Engineering, Bengaluru, Amrita Vishwa Vidyapeetham,Dept. of Mathematics,India","institution_ids":["https://openalex.org/I81556334"]},{"raw_affiliation_string":"Dept. of Mathematics, Amrita School of Engineering, Bengaluru, Amrita Vishwa Vidyapeetham, India","institution_ids":["https://openalex.org/I81556334"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028114665","display_name":"Amrita Thakur","orcid":"https://orcid.org/0000-0002-5293-3780"},"institutions":[{"id":"https://openalex.org/I81556334","display_name":"Amrita Vishwa Vidyapeetham","ror":"https://ror.org/03am10p12","country_code":"IN","type":"education","lineage":["https://openalex.org/I81556334"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Amrita Thakur","raw_affiliation_strings":["Amrita School of Engineering, Bengaluru, Amrita Vishwa Vidyapeetham,Dept. of Chemistry,India","Dept. of Chemistry, Amrita School of Engineering, Bengaluru, Amrita Vishwa Vidyapeetham, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amrita School of Engineering, Bengaluru, Amrita Vishwa Vidyapeetham,Dept. of Chemistry,India","institution_ids":["https://openalex.org/I81556334"]},{"raw_affiliation_string":"Dept. of Chemistry, Amrita School of Engineering, Bengaluru, Amrita Vishwa Vidyapeetham, India","institution_ids":["https://openalex.org/I81556334"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073553489","display_name":"Nidhin Prabhakar Tv","orcid":null},"institutions":[{"id":"https://openalex.org/I81556334","display_name":"Amrita Vishwa Vidyapeetham","ror":"https://ror.org/03am10p12","country_code":"IN","type":"education","lineage":["https://openalex.org/I81556334"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nidhin Prabhakar Tv","raw_affiliation_strings":["Amrita School of Computing,Dept. of Computer Science and Engineering","Dept. of Computer Science and Engineering, Amrita School of Computing"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amrita School of Computing,Dept. of Computer Science and Engineering","institution_ids":["https://openalex.org/I81556334"]},{"raw_affiliation_string":"Dept. of Computer Science and Engineering, Amrita School of Computing","institution_ids":["https://openalex.org/I81556334"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.3907,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.95908733,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9866999983787537,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.7570905685424805},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.643171489238739},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6289772987365723},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6064845323562622},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5694835186004639},{"id":"https://openalex.org/keywords/decision-tree","display_name":"Decision tree","score":0.529017448425293},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.48094862699508667},{"id":"https://openalex.org/keywords/naive-bayes-classifier","display_name":"Naive Bayes classifier","score":0.4649331271648407},{"id":"https://openalex.org/keywords/inheritance","display_name":"Inheritance (genetic algorithm)","score":0.41842931509017944},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.38400760293006897},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3622378706932068},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.33103716373443604},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22120952606201172},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1426888108253479}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.7570905685424805},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.643171489238739},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6289772987365723},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6064845323562622},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5694835186004639},{"id":"https://openalex.org/C84525736","wikidata":"https://www.wikidata.org/wiki/Q831366","display_name":"Decision tree","level":2,"score":0.529017448425293},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.48094862699508667},{"id":"https://openalex.org/C52001869","wikidata":"https://www.wikidata.org/wiki/Q812530","display_name":"Naive Bayes classifier","level":3,"score":0.4649331271648407},{"id":"https://openalex.org/C2780902518","wikidata":"https://www.wikidata.org/wiki/Q6033780","display_name":"Inheritance (genetic algorithm)","level":3,"score":0.41842931509017944},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.38400760293006897},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3622378706932068},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33103716373443604},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22120952606201172},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1426888108253479}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/icccnt54827.2022.9984600","is_oa":false,"landing_page_url":"https://doi.org/10.1109/icccnt54827.2022.9984600","pdf_url":null,"source":{"id":"https://openalex.org/S4363607876","display_name":"2022 13th International Conference on Computing Communication and Networking Technologies (ICCCNT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 13th International Conference on Computing Communication and Networking Technologies (ICCCNT)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land","score":0.6399999856948853}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1598068104","https://openalex.org/W1915129189","https://openalex.org/W1963795510","https://openalex.org/W2025302387","https://openalex.org/W2158485828","https://openalex.org/W2778455075","https://openalex.org/W2808601429","https://openalex.org/W2937669142","https://openalex.org/W2992718816","https://openalex.org/W3017044142","https://openalex.org/W3028860567","https://openalex.org/W3088233101","https://openalex.org/W3088694469","https://openalex.org/W3089599917","https://openalex.org/W3116420205","https://openalex.org/W3121315275","https://openalex.org/W3203698729","https://openalex.org/W4206206241","https://openalex.org/W6747530153","https://openalex.org/W6761264471"],"related_works":["https://openalex.org/W4200112873","https://openalex.org/W4367336074","https://openalex.org/W2955796858","https://openalex.org/W4224941037","https://openalex.org/W3154045278","https://openalex.org/W4379620016","https://openalex.org/W3210764983","https://openalex.org/W4367335949","https://openalex.org/W3089416646","https://openalex.org/W2004826645"],"abstract_inverted_index":{"Cancer":[0],"classification":[1,47,83],"is":[2,41,59,84,125,144],"in":[3,8,18,24,30,127],"the":[4,9,99,107,134,168,173,178],"spotlight":[5],"of":[6,38,78,106,109],"research":[7],"medical":[10],"domain;":[11],"genetic":[12],"inheritance":[13],"plays":[14],"a":[15,94],"significant":[16],"role":[17],"causing":[19],"this":[20,39,128],"condition.":[21],"Certain":[22],"similarities":[23],"DNA":[25],"sequence":[26],"can":[27],"be":[28],"prevalent":[29],"individuals":[31],"who":[32],"have":[33],"cancer.":[34],"The":[35,82],"foremost":[36],"intention":[37],"paper":[40],"to":[42,69,171],"put":[43],"forth":[44],"efficient":[45],"cancer":[46,179],"techniques":[48],"that":[49,58,153],"provide":[50],"steady":[51],"and":[52,164,175],"substantial":[53],"accuracy.":[54],"An":[55],"unconventional":[56],"factor":[57],"RNA-seq":[60,88],"gene":[61],"expression":[62],"levels":[63,91],"are":[64],"considered":[65],"here":[66],"as":[67,73,137],"opposed":[68],"familiar":[70],"factors":[71],"such":[72],"physical":[74],"features":[75],"or":[76],"results":[77],"various":[79,110,147],"imagery":[80,148],"techniques.":[81,149],"conducted":[85,126],"by":[86,93],"analyzing":[87],"Gene":[89],"Expression":[90],"measured":[92],"powerful":[95],"sequencing":[96],"system":[97],"called":[98],"Illumina":[100],"Hiseq":[101],"platform.":[102],"A":[103],"comparative":[104],"study":[105],"application":[108],"machine":[111],"learning":[112],"algorithms":[113],"-":[114],"Decision":[115],"Tree,":[116],"Random":[117],"Forest,":[118],"SVM,":[119],"KNN,":[120],"Na\u00efve":[121],"Bayes,":[122],"Multinomial":[123],"Regression":[124],"paper.":[129],"This":[130],"method":[131],"significantly":[132],"reduces":[133],"computational":[135],"complexity":[136],"against":[138],"deep":[139],"neural":[140],"network":[141],"approach":[142],"which":[143],"used":[145],"with":[146],"Experimental":[150],"observations":[151],"suggest":[152],"SVM":[154],"provides":[155],"higher":[156],"accuracy,":[157],"cross-validation":[158],"score,":[159],"nearly":[160],"ideal":[161],"AUC-ROC":[162],"curves,":[163],"better":[165],"performance":[166],"concerning":[167],"time":[169],"required":[170],"fit":[172],"model":[174],"subsequently":[176],"predict":[177],"type.":[180]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}