{"id":"https://openalex.org/W1979383755","doi":"https://doi.org/10.1109/iccabs.2012.6182635","title":"Decision procedure based discovery of rare behaviors in Stochastic Differential Equation models of biological systems","display_name":"Decision procedure based discovery of rare behaviors in Stochastic Differential Equation models of biological systems","publication_year":2012,"publication_date":"2012-02-01","ids":{"openalex":"https://openalex.org/W1979383755","doi":"https://doi.org/10.1109/iccabs.2012.6182635","mag":"1979383755"},"language":"en","primary_location":{"id":"doi:10.1109/iccabs.2012.6182635","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iccabs.2012.6182635","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE 2nd International Conference on Computational Advances in Bio and medical Sciences (ICCABS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://stars.library.ucf.edu/scopus2010/5299","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013665481","display_name":"Arup Ghosh","orcid":"https://orcid.org/0000-0003-3259-0124"},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arup K. Ghosh","raw_affiliation_strings":["EECS Department, University of Central Florida, Orlando, FL, USA","EECS Department, University of Central Florida, Orlando, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EECS Department, University of Central Florida, Orlando, FL, USA","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"EECS Department, University of Central Florida, Orlando, USA#TAB#","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081485727","display_name":"Faraz Hussain","orcid":"https://orcid.org/0000-0001-8971-1850"},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Faraz Hussain","raw_affiliation_strings":["EECS Department, University of Central Florida, Orlando, FL, USA","EECS Department, University of Central Florida, Orlando, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EECS Department, University of Central Florida, Orlando, FL, USA","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"EECS Department, University of Central Florida, Orlando, USA#TAB#","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075978538","display_name":"Sumit Kumar Jha","orcid":"https://orcid.org/0000-0003-0354-2940"},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sumit K. Jha","raw_affiliation_strings":["EECS Department, University of California Berkeley, Berkeley, CA, USA","EECS Department, University of Central Florida, Orlando, FL, USA","EECS Department, University of Central Florida, Orlando, USA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EECS Department, University of California Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"EECS Department, University of Central Florida, Orlando, FL, USA","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"EECS Department, University of Central Florida, Orlando, USA#TAB#","institution_ids":["https://openalex.org/I106165777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042353780","display_name":"Christopher J. Langmead","orcid":"https://orcid.org/0000-0001-7521-6736"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher J. Langmead","raw_affiliation_strings":["Computer Science Department, Carnegie Mellon University, Pittsburgh, PA, USA","[Computer Science Dept., Carnegie Mellon University, Pittsburgh, PA, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science Department, Carnegie Mellon University, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"[Computer Science Dept., Carnegie Mellon University, Pittsburgh, PA, USA]","institution_ids":["https://openalex.org/I74973139"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035902535","display_name":"Susmit Jha","orcid":"https://orcid.org/0000-0001-5983-9095"},"institutions":[{"id":"https://openalex.org/I106165777","display_name":"University of Central Florida","ror":"https://ror.org/036nfer12","country_code":"US","type":"education","lineage":["https://openalex.org/I106165777"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susmit Jha","raw_affiliation_strings":["EECS Department, University of California Berkeley, Berkeley, CA, USA","EECS Department, University of Central Florida, Orlando, FL, USA","EECS Department, UC Berkeley, CA 94709, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EECS Department, University of California Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"EECS Department, University of Central Florida, Orlando, FL, USA","institution_ids":["https://openalex.org/I106165777"]},{"raw_affiliation_string":"EECS Department, UC Berkeley, CA 94709, USA","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5013665481"],"corresponding_institution_ids":["https://openalex.org/I106165777"],"apc_list":null,"apc_paid":null,"fwci":0.4034,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.60960085,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"206","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10142","display_name":"Formal Methods in Verification","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11195","display_name":"Simulation Techniques and Applications","score":0.9815000295639038,"subfield":{"id":"https://openalex.org/subfields/1803","display_name":"Management Science and Operations Research"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rare-events","display_name":"Rare events","score":0.7232115268707275},{"id":"https://openalex.org/keywords/bounding-overwatch","display_name":"Bounding overwatch","score":0.7095996141433716},{"id":"https://openalex.org/keywords/stochastic-differential-equation","display_name":"Stochastic differential equation","score":0.7051633596420288},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6679345369338989},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.5118831396102905},{"id":"https://openalex.org/keywords/stochastic-modelling","display_name":"Stochastic modelling","score":0.4915662705898285},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.4577014446258545},{"id":"https://openalex.org/keywords/gaussian","display_name":"Gaussian","score":0.42801788449287415},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.39038392901420593},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.34280335903167725},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.32448309659957886},{"id":"https://openalex.org/keywords/applied-mathematics","display_name":"Applied mathematics","score":0.3073704242706299},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.29273170232772827},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2865447998046875},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.1383274793624878}],"concepts":[{"id":"https://openalex.org/C2777317252","wikidata":"https://www.wikidata.org/wiki/Q18393516","display_name":"Rare events","level":2,"score":0.7232115268707275},{"id":"https://openalex.org/C63584917","wikidata":"https://www.wikidata.org/wiki/Q333286","display_name":"Bounding overwatch","level":2,"score":0.7095996141433716},{"id":"https://openalex.org/C51955184","wikidata":"https://www.wikidata.org/wiki/Q1545585","display_name":"Stochastic differential equation","level":2,"score":0.7051633596420288},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6679345369338989},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.5118831396102905},{"id":"https://openalex.org/C127491075","wikidata":"https://www.wikidata.org/wiki/Q7617825","display_name":"Stochastic modelling","level":2,"score":0.4915662705898285},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.4577014446258545},{"id":"https://openalex.org/C163716315","wikidata":"https://www.wikidata.org/wiki/Q901177","display_name":"Gaussian","level":2,"score":0.42801788449287415},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.39038392901420593},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.34280335903167725},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.32448309659957886},{"id":"https://openalex.org/C28826006","wikidata":"https://www.wikidata.org/wiki/Q33521","display_name":"Applied mathematics","level":1,"score":0.3073704242706299},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.29273170232772827},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2865447998046875},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1383274793624878},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/iccabs.2012.6182635","is_oa":false,"landing_page_url":"https://doi.org/10.1109/iccabs.2012.6182635","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE 2nd International Conference on Computational Advances in Bio and medical Sciences (ICCABS)","raw_type":"proceedings-article"},{"id":"pmh:oai:stars.library.ucf.edu:scopus2010-6298","is_oa":true,"landing_page_url":"https://stars.library.ucf.edu/scopus2010/5299","pdf_url":null,"source":{"id":"https://openalex.org/S4210172555","display_name":"Journal of International Crisis and Risk Communication Research","issn_l":"2576-0017","issn":["2576-0017","2576-0025"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus Export 2010-2014","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.434.1622","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.434.1622","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.eecs.ucf.edu/~fhussain/pubs/rarebehaviors_iccabs2012.pdf","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:stars.library.ucf.edu:scopus2010-6298","is_oa":true,"landing_page_url":"https://stars.library.ucf.edu/scopus2010/5299","pdf_url":null,"source":{"id":"https://openalex.org/S4210172555","display_name":"Journal of International Crisis and Risk Communication Research","issn_l":"2576-0017","issn":["2576-0017","2576-0025"],"is_oa":true,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus Export 2010-2014","raw_type":"text"},"sustainable_development_goals":[{"score":0.7799999713897705,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W92576581","https://openalex.org/W125598877","https://openalex.org/W1485584666","https://openalex.org/W1504091984","https://openalex.org/W1520566118","https://openalex.org/W1569248486","https://openalex.org/W1580561995","https://openalex.org/W1590683704","https://openalex.org/W1926206757","https://openalex.org/W2023808162","https://openalex.org/W2111695544","https://openalex.org/W2117863556","https://openalex.org/W2118039525","https://openalex.org/W2134734244","https://openalex.org/W2136445042","https://openalex.org/W2165214723","https://openalex.org/W6628999359","https://openalex.org/W6635347639","https://openalex.org/W6640293377","https://openalex.org/W6677277993","https://openalex.org/W6684552117"],"related_works":["https://openalex.org/W2141892977","https://openalex.org/W4283744928","https://openalex.org/W2595984260","https://openalex.org/W2042280983","https://openalex.org/W171914860","https://openalex.org/W2321888438","https://openalex.org/W2888652631","https://openalex.org/W4388552250","https://openalex.org/W2060317829","https://openalex.org/W1995427843"],"abstract_inverted_index":{"Stochastic":[0],"Differential":[1],"Equation":[2],"(SDE)":[3],"models":[4,21],"are":[5,26,77],"often":[6,33],"used":[7],"to":[8,42,66,120,156],"model":[9],"the":[10,34,52,58,67,78,86,92,99,102,122,136,150,166,173],"dynamics":[11],"of":[12,19,54,60,70,88,94,101,124,138,145,152,168,175],"complex":[13],"biological":[14],"systems.":[15],"The":[16],"stochastic":[17,75,95],"nature":[18],"these":[20],"means":[22,81],"that":[23,36,116],"some":[24],"behaviors":[25,128,144],"more":[27],"likely":[28],"than":[29],"others.":[30],"It":[31],"is":[32,41,117],"case":[35],"a":[37,55,61,112],"model's":[38],"primary":[39],"purpose":[40],"study":[43],"rare":[44,89,125,143],"but":[45,126],"interesting":[46,127],"or":[47,57],"important":[48],"behaviors,":[49],"such":[50],"as":[51],"formation":[53],"tumor,":[56],"failure":[59],"cyber-physical":[62],"system.":[63],"Unfortunately,":[64],"due":[65],"limited":[68],"availability":[69],"analytic":[71],"methods":[72],"for":[73,82,141],"SDEs,":[74],"simulations":[76,96],"most":[79],"common":[80],"estimating":[83],"(or":[84],"bounding)":[85],"probability":[87,167],"behaviors.":[90],"Naturally,":[91],"cost":[93],"increases":[97],"with":[98],"rarity":[100],"behavior":[103,171],"under":[104,172],"consideration.":[105],"To":[106],"address":[107],"this":[108],"problem,":[109],"we":[110],"introduce":[111],"new":[113],"algorithm,":[114],"RESERCHE,":[115],"specifically":[118],"designed":[119],"quantify":[121],"likelihood":[123],"in":[129],"SDE":[130],"models.":[131],"Our":[132],"approach":[133],"relies":[134],"on":[135,149],"use":[137],"temporal":[139],"logics":[140],"specifying":[142],"possible":[146],"interest,":[147],"and":[148],"ability":[151],"bit-vector":[153],"decision":[154],"procedures":[155],"reason":[157],"exhaustively":[158],"about":[159],"fixed":[160],"precision":[161],"arithmetic.":[162],"We":[163],"also":[164],"compute":[165],"an":[169],"observed":[170],"assumption":[174],"Gaussian":[176],"noise.":[177]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-04-28T14:05:53.105641","created_date":"2025-10-10T00:00:00"}