{"id":"https://openalex.org/W4400114682","doi":"https://doi.org/10.1109/i2mtc60896.2024.10560686","title":"Integrating radiomics and immunology: non-invasive assessment of CD8+ T cell levels","display_name":"Integrating radiomics and immunology: non-invasive assessment of CD8+ T cell levels","publication_year":2024,"publication_date":"2024-05-20","ids":{"openalex":"https://openalex.org/W4400114682","doi":"https://doi.org/10.1109/i2mtc60896.2024.10560686"},"language":"en","primary_location":{"id":"doi:10.1109/i2mtc60896.2024.10560686","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/i2mtc60896.2024.10560686","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Instrumentation and Measurement Technology Conference (I2MTC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082509547","display_name":"Amir L. Rifi","orcid":"https://orcid.org/0000-0002-4519-6292"},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Amir L. Rifi","raw_affiliation_strings":["Research Group Biostatistics and Medical Informatics (BISI) Vrije Universiteit Brussel,Brussels,Belgium"],"affiliations":[{"raw_affiliation_string":"Research Group Biostatistics and Medical Informatics (BISI) Vrije Universiteit Brussel,Brussels,Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058395022","display_name":"Camille Raets","orcid":"https://orcid.org/0000-0002-6620-1169"},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Camille Raets","raw_affiliation_strings":["Research Group Biostatistics and Medical Informatics (BISI) Vrije Universiteit Brussel,Brussels,Belgium"],"affiliations":[{"raw_affiliation_string":"Research Group Biostatistics and Medical Informatics (BISI) Vrije Universiteit Brussel,Brussels,Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009369215","display_name":"In\u00e8s Dufait","orcid":"https://orcid.org/0000-0002-9945-4357"},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"In\u00e8s Dufait","raw_affiliation_strings":["Vrije Universiteit Brussel,Department of Radiotherapy, UZ Brussel,Brussels,Belgium"],"affiliations":[{"raw_affiliation_string":"Vrije Universiteit Brussel,Department of Radiotherapy, UZ Brussel,Brussels,Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040579751","display_name":"Mark De Ridder","orcid":"https://orcid.org/0000-0003-4433-8807"},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Mark De Ridder","raw_affiliation_strings":["Vrije Universiteit Brussel,Department of Radiotherapy, UZ Brussel,Brussels,Belgium"],"affiliations":[{"raw_affiliation_string":"Vrije Universiteit Brussel,Department of Radiotherapy, UZ Brussel,Brussels,Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019777536","display_name":"Kurt Barb\u00e9","orcid":"https://orcid.org/0000-0002-7825-9077"},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Kurt Barb\u00e9","raw_affiliation_strings":["Research Group Biostatistics and Medical Informatics (BISI) Vrije Universiteit Brussel,Brussels,Belgium"],"affiliations":[{"raw_affiliation_string":"Research Group Biostatistics and Medical Informatics (BISI) Vrije Universiteit Brussel,Brussels,Belgium","institution_ids":["https://openalex.org/I13469542"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5082509547"],"corresponding_institution_ids":["https://openalex.org/I13469542"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14562675,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9890000224113464,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9419999718666077,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiomics","display_name":"Radiomics","score":0.7226254940032959},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4453314244747162},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.40114539861679077},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3676639497280121},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.31047528982162476},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.25513792037963867},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.23135143518447876}],"concepts":[{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.7226254940032959},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4453314244747162},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.40114539861679077},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3676639497280121},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.31047528982162476},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25513792037963867},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.23135143518447876}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/i2mtc60896.2024.10560686","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/i2mtc60896.2024.10560686","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Instrumentation and Measurement Technology Conference (I2MTC)","raw_type":"proceedings-article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:182342","is_oa":false,"landing_page_url":"https://biblio.vub.ac.be/vubir/integrating-radiomics-and-immunology-noninvasive-assessment-of-cd8-t-cell-levels(faf2c8f1-4fdd-4f6e-8c9c-1c957b894a73).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:211623","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7200000286102295,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1532190565","https://openalex.org/W1859257957","https://openalex.org/W1970343639","https://openalex.org/W1986129954","https://openalex.org/W1996796871","https://openalex.org/W2140683554","https://openalex.org/W2142300779","https://openalex.org/W2150575159","https://openalex.org/W2160643014","https://openalex.org/W2350997045","https://openalex.org/W2763355946","https://openalex.org/W2793785683","https://openalex.org/W2998789541","https://openalex.org/W3025181063","https://openalex.org/W3027709702","https://openalex.org/W4213031714","https://openalex.org/W4214920103","https://openalex.org/W4292862938","https://openalex.org/W4307086007","https://openalex.org/W4366668365","https://openalex.org/W6777847980"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725"],"abstract_inverted_index":{"Radiomic":[0],"features,":[1,80],"commonly":[2],"used":[3],"in":[4,11],"machine":[5],"learning":[6],"models,":[7],"have":[8],"demonstrated":[9],"efficacy":[10],"predicting":[12],"tumor-related":[13],"outcomes.":[14],"Nonetheless,":[15],"the":[16,36,48,57,66,74,85,102,130,140,144],"clinical":[17],"application":[18],"of":[19,39,51,59,78,104,114,129,133,147],"these":[20,40,88],"features":[21],"is":[22],"impeded":[23],"by":[24],"their":[25,92],"inherent":[26],"non-biological":[27],"interpretability.":[28],"It":[29],"is,":[30],"therefore,":[31],"critically":[32],"important":[33],"to":[34,83,101,125,142],"unravel":[35],"biological":[37,94],"meaning":[38],"radiomic":[41,79],"features.":[42],"In":[43],"this":[44],"paper,":[45],"we":[46,81],"modulate":[47],"tumor":[49],"microenvironment":[50],"a":[52,111],"murine":[53],"cancer":[54],"model":[55],"through":[56],"administration":[58],"monoclonal":[60],"antibodies,":[61],"subsequently":[62],"imaging":[63],"and":[64,76,91,135],"isolating":[65],"tumors":[67],"for":[68],"CD8+":[69,115],"T":[70,116],"cell":[71,117],"quantification.":[72],"Through":[73],"extraction":[75,103],"analysis":[77,99],"seek":[82],"bridge":[84],"gap":[86],"between":[87],"quantitative":[89],"variables":[90],"underlying":[93],"meaning.":[95],"An":[96],"exploratory":[97],"factor":[98],"leads":[100],"two":[105],"factors.":[106],"Factor":[107],"2":[108],"emerges":[109],"as":[110],"potential":[112,132],"indicator":[113],"levels.":[118],"These":[119],"encouraging":[120],"results":[121],"not":[122],"only":[123],"contribute":[124],"advancing":[126],"our":[127],"understanding":[128],"synergistic":[131],"immunology":[134],"radiomics":[136],"but":[137],"also":[138],"establish":[139],"foundation":[141],"address":[143],"explainability":[145],"issue":[146],"radiomics-based":[148],"prediction":[149],"models.":[150]},"counts_by_year":[],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}