{"id":"https://openalex.org/W3012425414","doi":"https://doi.org/10.1109/ghtc46095.2019.9033017","title":"A Low-Cost, Point-of-Care Sickle Cell Anemia Screening Device for Use in Low and Middle-Income Countries","display_name":"A Low-Cost, Point-of-Care Sickle Cell Anemia Screening Device for Use in Low and Middle-Income Countries","publication_year":2019,"publication_date":"2019-10-01","ids":{"openalex":"https://openalex.org/W3012425414","doi":"https://doi.org/10.1109/ghtc46095.2019.9033017","mag":"3012425414"},"language":"en","primary_location":{"id":"doi:10.1109/ghtc46095.2019.9033017","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ghtc46095.2019.9033017","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE Global Humanitarian Technology Conference (GHTC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005163061","display_name":"Jannah Wing","orcid":null},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jannah Wing","raw_affiliation_strings":["Healthcare Systems Engineering, Lehigh University Bethlehem, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Healthcare Systems Engineering, Lehigh University Bethlehem, PA, USA","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011666883","display_name":"Ashleigh J. Crawford","orcid":"https://orcid.org/0000-0001-9048-0113"},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashleigh Crawford","raw_affiliation_strings":["Bioengineering, Lehigh University, Bethlehem, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering, Lehigh University, Bethlehem, PA, USA","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086092052","display_name":"Maria Rosaria Lancia","orcid":"https://orcid.org/0000-0002-6384-8311"},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria Lancia","raw_affiliation_strings":["Bioengineering, Lehigh University, Bethlehem, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering, Lehigh University, Bethlehem, PA, USA","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049749799","display_name":"Paola Lopez","orcid":null},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paola Lopez","raw_affiliation_strings":["Materials Science & Engineering, Lehigh University, Bethlehem, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Materials Science & Engineering, Lehigh University, Bethlehem, PA, USA","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076359005","display_name":"Olivia O'Donnell","orcid":null},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivia O'Donnell","raw_affiliation_strings":["Bioengineering, Lehigh University, Bethlehem, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering, Lehigh University, Bethlehem, PA, USA","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036921880","display_name":"Jaro Perera","orcid":null},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaro Perera","raw_affiliation_strings":["Bioengineering, Lehigh University, Bethlehem, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering, Lehigh University, Bethlehem, PA, USA","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104217173","display_name":"Khanjan Mehta","orcid":null},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Khanjan Mehta","raw_affiliation_strings":["Office of the Vice Provost for Creative Inquiry, Lehigh University, Bethlehem, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Office of the Vice Provost for Creative Inquiry, Lehigh University, Bethlehem, PA, USA","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013411400","display_name":"Xuanhong Cheng","orcid":"https://orcid.org/0000-0002-6331-8572"},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xuanhong Cheng","raw_affiliation_strings":["Materials Science & Engineering, Lehigh University, Bethlehem, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Materials Science & Engineering, Lehigh University, Bethlehem, PA, USA","institution_ids":["https://openalex.org/I186143895"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5005163061"],"corresponding_institution_ids":["https://openalex.org/I186143895"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.27725507,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"15","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.974399983882904,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/life-expectancy","display_name":"Life expectancy","score":0.7080294489860535},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5966622233390808},{"id":"https://openalex.org/keywords/anemia","display_name":"Anemia","score":0.5737990140914917},{"id":"https://openalex.org/keywords/sickle-cell-anemia","display_name":"Sickle cell anemia","score":0.5631830096244812},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5393476486206055},{"id":"https://openalex.org/keywords/low-and-middle-income-countries","display_name":"Low and middle income countries","score":0.46901935338974},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.4345744848251343},{"id":"https://openalex.org/keywords/developing-country","display_name":"Developing country","score":0.3695012629032135},{"id":"https://openalex.org/keywords/pediatrics","display_name":"Pediatrics","score":0.34549012780189514},{"id":"https://openalex.org/keywords/environmental-health","display_name":"Environmental health","score":0.2628917396068573},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.1950511932373047},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.13195863366127014},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.12833747267723083},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.119832843542099}],"concepts":[{"id":"https://openalex.org/C133925201","wikidata":"https://www.wikidata.org/wiki/Q188419","display_name":"Life expectancy","level":3,"score":0.7080294489860535},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5966622233390808},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.5737990140914917},{"id":"https://openalex.org/C2778620579","wikidata":"https://www.wikidata.org/wiki/Q185034","display_name":"Sickle cell anemia","level":3,"score":0.5631830096244812},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5393476486206055},{"id":"https://openalex.org/C3018472363","wikidata":"https://www.wikidata.org/wiki/Q177323","display_name":"Low and middle income countries","level":3,"score":0.46901935338974},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4345744848251343},{"id":"https://openalex.org/C83864248","wikidata":"https://www.wikidata.org/wiki/Q177323","display_name":"Developing country","level":2,"score":0.3695012629032135},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.34549012780189514},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.2628917396068573},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1950511932373047},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.13195863366127014},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12833747267723083},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.119832843542099},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/ghtc46095.2019.9033017","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ghtc46095.2019.9033017","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE Global Humanitarian Technology Conference (GHTC)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"No poverty","id":"https://metadata.un.org/sdg/1","score":0.47999998927116394}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W610126998","https://openalex.org/W1763433851","https://openalex.org/W2103522837","https://openalex.org/W2161448604","https://openalex.org/W2616283505","https://openalex.org/W2751808856","https://openalex.org/W2902147263","https://openalex.org/W2911481594","https://openalex.org/W6675643527"],"related_works":["https://openalex.org/W16271281","https://openalex.org/W40019356","https://openalex.org/W2406455777","https://openalex.org/W2073743814","https://openalex.org/W3013519900","https://openalex.org/W4292066684","https://openalex.org/W2035174274","https://openalex.org/W2357219879","https://openalex.org/W2051134735","https://openalex.org/W1895899363"],"abstract_inverted_index":{"Sickle":[0],"cell":[1,135,173,206],"disease":[2,28],"(SCD)":[3],"is":[4,29,44,121],"a":[5,92,129,143,193,204],"common":[6,31],"and":[7,23,59,89,107,148,160,163,171,200],"life-threatening":[8],"inherited":[9],"blood":[10],"disorder":[11],"which":[12,195],"can":[13],"cause":[14],"anemia,":[15],"pain,":[16],"organ":[17],"damage,":[18],"increased":[19],"risk":[20],"for":[21,209],"infection,":[22],"reduced":[24],"life":[25],"expectancy.":[26],"This":[27],"especially":[30],"in":[32,63,83,98,123,146,182,189,211],"sub-Saharan":[33,99],"Africa,":[34],"where":[35],"estimates":[36],"suggest":[37],"that":[38],"the":[39,51,73,124,197],"mortality":[40],"rate":[41],"among":[42],"children":[43],"as":[45,47,142],"high":[46,55],"50-90%":[48],"depending":[49],"on":[50,157],"location.":[52],"Despite":[53],"this":[54,117,119],"mortality,":[56],"universal":[57],"screening":[58,96,144,207],"early":[60],"intervention":[61],"programs":[62,97],"high-income":[64],"countries":[65,150],"have":[66,153],"proven":[67],"to":[68,110,115,139,191],"be":[69,140],"effective":[70],"at":[71],"reducing":[72],"probability":[74],"of":[75,127,203],"death.":[76],"The":[77],"primary":[78],"SCD":[79,95],"diagnostic":[80,137],"methods":[81],"used":[82,141],"these":[84],"areas,":[85],"however,":[86],"are":[87],"expensive":[88],"resource-heavy.":[90],"As":[91],"result,":[93],"implementing":[94],"Africa":[100],"has":[101,179],"thus":[102],"far":[103,155],"been":[104,180],"challenging,":[105],"expensive,":[106],"limited":[108],"only":[109],"small-scale":[111],"programs.":[112],"In":[113,176],"order":[114,190],"address":[116],"need,":[118],"project":[120],"currently":[122],"concept":[125],"stage":[126],"designing":[128],"low-cost,":[130],"easy-to-use,":[131],"lateral":[132,185],"flow":[133,186],"sickle":[134,172,205],"anemia":[136],"test":[138],"device":[145,187,208],"low":[147],"middle-income":[149],"(LMICs).":[151],"Efforts":[152],"so":[154],"focused":[156],"finding":[158],"sensitive":[159],"specific":[161],"capture":[162],"detection":[164],"antibody":[165],"pairs":[166],"targeting":[167],"normal":[168],"hemoglobin":[169,174],"A":[170],"S.":[175],"addition,":[177],"progress":[178],"made":[181],"testing":[183],"different":[184],"configurations":[188],"establish":[192],"design":[194],"meets":[196],"economic,":[198],"usability,":[199],"reliability":[201],"demands":[202],"use":[210],"LMICs.":[212]},"counts_by_year":[{"year":2024,"cited_by_count":2}],"updated_date":"2026-05-05T08:41:31.759640","created_date":"2025-10-10T00:00:00"}