{"id":"https://openalex.org/W2143532590","doi":"https://doi.org/10.1109/gensips.2010.5719669","title":"Finding steady states of large scale regulatory networks through partitioning","display_name":"Finding steady states of large scale regulatory networks through partitioning","publication_year":2010,"publication_date":"2010-11-01","ids":{"openalex":"https://openalex.org/W2143532590","doi":"https://doi.org/10.1109/gensips.2010.5719669","mag":"2143532590"},"language":"en","primary_location":{"id":"doi:10.1109/gensips.2010.5719669","is_oa":false,"landing_page_url":"https://doi.org/10.1109/gensips.2010.5719669","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036380790","display_name":"Ferhat Ay","orcid":"https://orcid.org/0000-0002-0708-6914"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F Ay","raw_affiliation_strings":["Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA","Computer & Information Science & Engineering, University of Florida, Gainesville, 32611, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Computer & Information Science & Engineering, University of Florida, Gainesville, 32611, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000929673","display_name":"G\u00fcnhan G\u00fclsoy","orcid":"https://orcid.org/0000-0001-8482-2930"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G Gulsoy","raw_affiliation_strings":["Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA","Computer & Information Science & Engineering, University of Florida, Gainesville, 32611, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Computer & Information Science & Engineering, University of Florida, Gainesville, 32611, USA","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091769289","display_name":"Tamer Kahveci","orcid":"https://orcid.org/0000-0002-4403-8612"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T Kahveci","raw_affiliation_strings":["Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA","Computer & Information Science & Engineering, University of Florida, Gainesville, 32611, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Computer & Information Science & Engineering, University of Florida, Gainesville, 32611, USA","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I33213144"],"apc_list":null,"apc_paid":null,"fwci":2.7708,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.90278184,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9889000058174133,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/steady-state","display_name":"Steady state (chemistry)","score":0.8228281736373901},{"id":"https://openalex.org/keywords/component","display_name":"Component (thermodynamics)","score":0.6839519739151001},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6272314786911011},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5025594234466553},{"id":"https://openalex.org/keywords/biological-network","display_name":"Biological network","score":0.5024247169494629},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.4953542947769165},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.4772769808769226},{"id":"https://openalex.org/keywords/exploit","display_name":"Exploit","score":0.412169873714447},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.3728351593017578},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.243477463722229},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.15868881344795227},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08666267991065979},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.07503458857536316}],"concepts":[{"id":"https://openalex.org/C8171440","wikidata":"https://www.wikidata.org/wiki/Q903414","display_name":"Steady state (chemistry)","level":2,"score":0.8228281736373901},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.6839519739151001},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6272314786911011},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5025594234466553},{"id":"https://openalex.org/C28225019","wikidata":"https://www.wikidata.org/wiki/Q4915005","display_name":"Biological network","level":2,"score":0.5024247169494629},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.4953542947769165},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.4772769808769226},{"id":"https://openalex.org/C165696696","wikidata":"https://www.wikidata.org/wiki/Q11287","display_name":"Exploit","level":2,"score":0.412169873714447},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.3728351593017578},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.243477463722229},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.15868881344795227},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08666267991065979},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07503458857536316},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/gensips.2010.5719669","is_oa":false,"landing_page_url":"https://doi.org/10.1109/gensips.2010.5719669","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.4300000071525574,"display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1788683850","https://openalex.org/W2032811716","https://openalex.org/W2092264363","https://openalex.org/W2096766502","https://openalex.org/W2101296410","https://openalex.org/W2101428010","https://openalex.org/W2136559804"],"related_works":["https://openalex.org/W17155033","https://openalex.org/W3207760230","https://openalex.org/W1496222301","https://openalex.org/W1590307681","https://openalex.org/W2536018345","https://openalex.org/W4312814274","https://openalex.org/W4285370786","https://openalex.org/W2296488620","https://openalex.org/W2358353312","https://openalex.org/W2353836703"],"abstract_inverted_index":{"Identifying":[0],"steady":[1,26,51,74,99,158,169,191,227,240],"states":[2,27,52,100,159,170,192],"that":[3,91,143,181,236],"characterize":[4],"the":[5,73,80,92,109,113,122,153,157,175,190,194,200],"long":[6],"term":[7],"outcome":[8],"of":[9,28,53,65,101,106,108,115,121,148,160,193,202],"regulatory":[10,29,56,66,209,246],"networks":[11,30,67,210],"is":[12,31,124,130,184,206],"crucial":[13],"in":[14,68,222],"understanding":[15],"important":[16],"biological":[17],"processes":[18],"such":[19,90,162],"as":[20,36],"cellular":[21],"differentiation.":[22],"Finding":[23],"all":[24],"possible":[25],"a":[32,47,145],"computationally":[33],"intensive":[34],"task":[35],"it":[37],"suffers":[38],"from":[39,96,150],"state":[40,75,241],"space":[41],"explosion":[42],"problem.":[43],"Here,":[44],"we":[45,135],"propose":[46],"method":[48,59,238],"for":[49],"finding":[50],"large-scale":[54],"Boolean":[55],"networks.":[57,247],"Our":[58,229],"exploits":[60],"scale-freeness":[61],"and":[62,155],"weak":[63],"connectivity":[64],"order":[69,223],"to":[70,152,224,243],"speed":[71],"up":[72],"search":[76],"through":[77],"partitioning.":[78],"In":[79,132],"trivial":[81],"case":[82],"where":[83],"network":[84,123,196],"has":[85],"more":[86,186],"than":[87,188],"one":[88,118,151],"component":[89,103,120,163],"components":[93,139,142],"are":[94,104],"disconnected":[95],"each":[97,102,161],"other,":[98],"independent":[105],"those":[107],"remaining":[110],"components.":[111],"When":[112],"size":[114],"at":[116,197],"least":[117],"connected":[119],"still":[125],"prohibitively":[126],"large,":[127],"further":[128],"partitioning":[129,216],"necessary.":[131],"this":[133,182,215],"case,":[134],"identify":[136],"weakly":[137],"dependent":[138],"(i.e.,":[140],"two":[141],"have":[144,212],"small":[146,213],"number":[147,201],"regulations":[149,176],"other)":[154],"calculate":[156],"independently.":[164],"We":[165,179],"then":[166],"combine":[167],"these":[168],"by":[171],"taking":[172],"into":[173],"account":[174],"connecting":[177,204],"them.":[178],"show":[180],"approach":[183],"much":[185],"efficient":[187],"calculating":[189],"whole":[195],"once":[198],"when":[199],"edges":[203],"them":[205],"small.":[207],"Since":[208],"often":[211],"in-degrees,":[214],"strategy":[217],"can":[218],"be":[219],"used":[220],"effectively":[221],"find":[225],"their":[226],"states.":[228],"experimental":[230],"results":[231],"on":[232],"real":[233],"datasets":[234],"demonstrate":[235],"our":[237],"leverages":[239],"identification":[242],"very":[244],"large":[245]},"counts_by_year":[{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}