{"id":"https://openalex.org/W4405489459","doi":"https://doi.org/10.1109/embc53108.2024.10782872","title":"Biophysical models of slowly and rapidly adapting mechanosensitive tactile afferents in human tongue","display_name":"Biophysical models of slowly and rapidly adapting mechanosensitive tactile afferents in human tongue","publication_year":2024,"publication_date":"2024-07-15","ids":{"openalex":"https://openalex.org/W4405489459","doi":"https://doi.org/10.1109/embc53108.2024.10782872","pmid":"https://pubmed.ncbi.nlm.nih.gov/40039071"},"language":"en","primary_location":{"id":"doi:10.1109/embc53108.2024.10782872","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782872","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057108566","display_name":"Merat Rezaei","orcid":"https://orcid.org/0009-0008-7576-7827"},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Merat Rezaei","raw_affiliation_strings":["University of Virginia,Systems and Information Engineering,Charlottesville,VA,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia,Systems and Information Engineering,Charlottesville,VA,USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063095534","display_name":"Brian G\u00fcthrie","orcid":"https://orcid.org/0000-0002-3508-4625"},"institutions":[{"id":"https://openalex.org/I4210109925","display_name":"Cargill (United States)","ror":"https://ror.org/01pcq0j68","country_code":"US","type":"company","lineage":["https://openalex.org/I4210109925"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian Guthrie","raw_affiliation_strings":["Cargill Corporation,Global Core Research,Plymouth,MN,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cargill Corporation,Global Core Research,Plymouth,MN,USA","institution_ids":["https://openalex.org/I4210109925"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078363658","display_name":"Gregory J. Gerling","orcid":"https://orcid.org/0000-0003-3137-3822"},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory J. Gerling","raw_affiliation_strings":["University of Virginia,Systems and Information Engineering,Charlottesville,VA,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Virginia,Systems and Information Engineering,Charlottesville,VA,USA","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5057108566"],"corresponding_institution_ids":["https://openalex.org/I51556381"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.23200125,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10914","display_name":"Tactile and Sensory Interactions","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10914","display_name":"Tactile and Sensory Interactions","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12032","display_name":"Multisensory perception and integration","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.9819999933242798,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mechanosensitive-channels","display_name":"Mechanosensitive channels","score":0.9278267621994019},{"id":"https://openalex.org/keywords/tongue","display_name":"Tongue","score":0.4786444902420044},{"id":"https://openalex.org/keywords/mechanoreceptor","display_name":"Mechanoreceptor","score":0.46677154302597046},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43662697076797485},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.3572133779525757},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.28531381487846375},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22640591859817505},{"id":"https://openalex.org/keywords/sensory-system","display_name":"Sensory system","score":0.10971617698669434},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.06465122103691101}],"concepts":[{"id":"https://openalex.org/C4001165","wikidata":"https://www.wikidata.org/wiki/Q6804689","display_name":"Mechanosensitive channels","level":4,"score":0.9278267621994019},{"id":"https://openalex.org/C2779744641","wikidata":"https://www.wikidata.org/wiki/Q9614","display_name":"Tongue","level":2,"score":0.4786444902420044},{"id":"https://openalex.org/C2779097085","wikidata":"https://www.wikidata.org/wiki/Q1348853","display_name":"Mechanoreceptor","level":3,"score":0.46677154302597046},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43662697076797485},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3572133779525757},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.28531381487846375},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22640591859817505},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.10971617698669434},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06465122103691101},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C50254741","wikidata":"https://www.wikidata.org/wiki/Q62536","display_name":"Ion channel","level":3,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008465","descriptor_name":"Mechanoreceptors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008465","descriptor_name":"Mechanoreceptors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008465","descriptor_name":"Mechanoreceptors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009475","descriptor_name":"Neurons, Afferent","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":true},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":true},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":true},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014059","descriptor_name":"Tongue","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014110","descriptor_name":"Touch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014110","descriptor_name":"Touch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014110","descriptor_name":"Touch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc53108.2024.10782872","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782872","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:40039071","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40039071","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.6700000166893005,"id":"https://metadata.un.org/sdg/2"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1968181716","https://openalex.org/W1987298241","https://openalex.org/W2002802137","https://openalex.org/W2092511662","https://openalex.org/W2097581740","https://openalex.org/W2111788117","https://openalex.org/W2131387169","https://openalex.org/W2137141150","https://openalex.org/W2163565585","https://openalex.org/W2270054980","https://openalex.org/W2410066438","https://openalex.org/W2729725437","https://openalex.org/W2810612961","https://openalex.org/W2895286527","https://openalex.org/W3041441694","https://openalex.org/W3136301155","https://openalex.org/W3141875265","https://openalex.org/W4212785487","https://openalex.org/W4238648450","https://openalex.org/W4319660588","https://openalex.org/W6684124110","https://openalex.org/W6725340250","https://openalex.org/W6808782437"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W4246138198","https://openalex.org/W2411037442","https://openalex.org/W631800256","https://openalex.org/W2049167990","https://openalex.org/W2097609518","https://openalex.org/W2045807490","https://openalex.org/W2049363804"],"abstract_inverted_index":{"Upon":[0],"contact,":[1],"the":[2,38,81,103,113,122,145,177,182],"spike":[3,106,119,129],"firing":[4,28,107,126],"patterns":[5,29,108,117],"of":[6,30,44,69,84,109,118,133,147,154,164,184],"touch":[7],"afferents":[8,111,165],"encode":[9],"object":[10,70],"attributes":[11],"such":[12,45],"as":[13,57,143],"force,":[14],"vibration,":[15],"and":[16,32,47,52,62,94,124,131,157,193],"spatial":[17],"geometry.":[18],"Computational":[19],"models":[20,73,104,171],"in":[21,86,166],"cutaneous":[22],"skin":[23],"have":[24],"sought":[25],"to":[26,59,65,80,180],"emulate":[27],"slowly":[31],"rapidly":[33],"adapting":[34],"afferents.":[35],"Herein,":[36],"for":[37,176],"tongue,":[39],"we":[40],"develop":[41],"biophysical":[42],"versions":[43],"models,":[46],"which":[48],"rely":[49],"upon":[50],"functions":[51],"parameters":[53],"with":[54,76,137],"physiological":[55],"relevance,":[56],"opposed":[58],"stimulus":[60],"features,":[61],"are":[63,74,172],"extendable":[64],"a":[66,152,162,173],"broad":[67],"range":[68,153],"interactions.":[71],"The":[72,100],"evaluated":[75],"mechanical":[77],"inputs":[78],"relevant":[79],"oral":[82,167],"processing":[83],"food,":[85],"particular,":[87],"across":[88,140,151],"stress":[89],"ranges":[90],"spanning":[91],"material":[92],"compliances":[93],"periodic":[95,155],"vibrations":[96],"emulating":[97],"surface":[98,191],"sliding.":[99],"results":[101],"indicate":[102],"recapitulate":[105],"human":[110],"innervating":[112],"tongue.":[114],"Moreover,":[115],"predicted":[116],"firing,":[120],"e.g.,":[121,188],"mean":[123],"peak":[125],"frequency,":[127],"first":[128],"latency,":[130],"number":[132,146],"spikes,":[134],"compare":[135],"favorably":[136],"neural":[138],"recordings":[139],"force":[141],"magnitudes,":[142],"do":[144],"spikes":[148],"per":[149],"cycle":[150],"amplitudes":[156],"frequencies.":[158],"For":[159],"extension":[160],"into":[161],"population":[163],"mucosa,":[168],"these":[169],"single-unit":[170],"starting":[174],"point":[175],"further":[178],"efforts":[179],"capture":[181],"encoding":[183],"higher-level":[185],"perceptible":[186],"attributes,":[187],"compliance,":[189],"geometry,":[190],"roughness,":[192],"movement":[194],"velocity.":[195]},"counts_by_year":[],"updated_date":"2026-05-12T08:28:47.272897","created_date":"2025-10-10T00:00:00"}