{"id":"https://openalex.org/W4405491818","doi":"https://doi.org/10.1109/embc53108.2024.10782776","title":"Flexible chip-based wearable sensors enhanced by gold nanoparticles for IFN-\u03b3 detection","display_name":"Flexible chip-based wearable sensors enhanced by gold nanoparticles for IFN-\u03b3 detection","publication_year":2024,"publication_date":"2024-07-15","ids":{"openalex":"https://openalex.org/W4405491818","doi":"https://doi.org/10.1109/embc53108.2024.10782776","pmid":"https://pubmed.ncbi.nlm.nih.gov/40039230"},"language":"en","primary_location":{"id":"doi:10.1109/embc53108.2024.10782776","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782776","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082613331","display_name":"Laicong Qiao","orcid":"https://orcid.org/0000-0001-8572-8495"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laicong Qiao","raw_affiliation_strings":["UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088113248","display_name":"Tianruo Guo","orcid":"https://orcid.org/0000-0001-6348-6771"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tianruo Guo","raw_affiliation_strings":["UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113331720","display_name":"Ruier Xue","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ruier Xue","raw_affiliation_strings":["UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026913646","display_name":"Rui Sang","orcid":"https://orcid.org/0000-0003-2002-7078"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rui Sang","raw_affiliation_strings":["UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028809157","display_name":"Danting Yang","orcid":"https://orcid.org/0000-0002-5635-6474"},"institutions":[{"id":"https://openalex.org/I109935558","display_name":"Ningbo University","ror":"https://ror.org/03et85d35","country_code":"CN","type":"education","lineage":["https://openalex.org/I109935558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Danting Yang","raw_affiliation_strings":["Ningbo University,School of Medicine,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ningbo University,School of Medicine,China","institution_ids":["https://openalex.org/I109935558"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110191677","display_name":"F\u0113i D\u00e8ng","orcid":"https://orcid.org/0000-0002-5385-083X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fei Deng","raw_affiliation_strings":["UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNSW,Graduate School of Biomedical Engineering and Tyree Institute of Health Engineering,Sydney,Australia","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2082,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.81725888,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10338","display_name":"Advanced Sensor and Energy Harvesting Materials","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.9882000088691711,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wearable-computer","display_name":"Wearable computer","score":0.7625327110290527},{"id":"https://openalex.org/keywords/lab-on-a-chip","display_name":"Lab-on-a-chip","score":0.5519737601280212},{"id":"https://openalex.org/keywords/colloidal-gold","display_name":"Colloidal gold","score":0.5502864122390747},{"id":"https://openalex.org/keywords/chip","display_name":"Chip","score":0.5339428782463074},{"id":"https://openalex.org/keywords/wearable-technology","display_name":"Wearable technology","score":0.5169222354888916},{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.5135272145271301},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.5030466914176941},{"id":"https://openalex.org/keywords/system-on-a-chip","display_name":"System on a chip","score":0.4746159613132477},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4170217514038086},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.4149740934371948},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.3491555452346802},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.1843167245388031},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.09539705514907837}],"concepts":[{"id":"https://openalex.org/C150594956","wikidata":"https://www.wikidata.org/wiki/Q1334829","display_name":"Wearable computer","level":2,"score":0.7625327110290527},{"id":"https://openalex.org/C138942068","wikidata":"https://www.wikidata.org/wiki/Q633261","display_name":"Lab-on-a-chip","level":3,"score":0.5519737601280212},{"id":"https://openalex.org/C104819515","wikidata":"https://www.wikidata.org/wiki/Q900961","display_name":"Colloidal gold","level":3,"score":0.5502864122390747},{"id":"https://openalex.org/C165005293","wikidata":"https://www.wikidata.org/wiki/Q1074500","display_name":"Chip","level":2,"score":0.5339428782463074},{"id":"https://openalex.org/C54290928","wikidata":"https://www.wikidata.org/wiki/Q4845080","display_name":"Wearable technology","level":3,"score":0.5169222354888916},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.5135272145271301},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5030466914176941},{"id":"https://openalex.org/C118021083","wikidata":"https://www.wikidata.org/wiki/Q610398","display_name":"System on a chip","level":2,"score":0.4746159613132477},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4170217514038086},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4149740934371948},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.3491555452346802},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.1843167245388031},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.09539705514907837}],"mesh":[{"descriptor_ui":"D000076251","descriptor_name":"Wearable Electronic Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000076251","descriptor_name":"Wearable Electronic Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000076251","descriptor_name":"Wearable Electronic Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056656","descriptor_name":"Lab-On-A-Chip Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056656","descriptor_name":"Lab-On-A-Chip Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056656","descriptor_name":"Lab-On-A-Chip Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057230","descriptor_name":"Limit of Detection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057230","descriptor_name":"Limit of Detection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc53108.2024.10782776","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782776","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:40039230","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40039230","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7","score":0.46000000834465027}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W2020947315","https://openalex.org/W2072488504","https://openalex.org/W2118742454","https://openalex.org/W2791443927","https://openalex.org/W2795833336","https://openalex.org/W2915511630","https://openalex.org/W3015925584","https://openalex.org/W3037856693","https://openalex.org/W3095125339","https://openalex.org/W3111069707","https://openalex.org/W4206372884","https://openalex.org/W4281783318","https://openalex.org/W4306145810","https://openalex.org/W4390498996"],"related_works":["https://openalex.org/W3090300519","https://openalex.org/W2514492205","https://openalex.org/W4250401876","https://openalex.org/W2943851981","https://openalex.org/W2566526749","https://openalex.org/W3047461507","https://openalex.org/W3126390843","https://openalex.org/W4245880644","https://openalex.org/W4312415459","https://openalex.org/W2528680939"],"abstract_inverted_index":{"Cytokines,":[0],"essential":[1],"regulatory":[2],"proteins":[3],"orchestrating":[4],"various":[5],"physiological":[6],"processes":[7],"and":[8,38,71,91,101,136,150,200,228],"immune":[9],"responses,":[10],"play":[11],"a":[12,55,65,79,110,122,129,137,156,173,217,226,236],"pivotal":[13],"role":[14],"in":[15,220,240],"assessing":[16],"health":[17,167,205,233],"status.":[18],"Conventional":[19],"cytokine":[20,60,182],"detection":[21,61,132,152],"methods,":[22],"such":[23],"as":[24],"enzyme-linked":[25],"immunosorbent":[26],"assays,":[27],"are":[28],"reliable":[29],"but":[30,41],"time-consuming.":[31],"Electrochemical":[32],"aptamer-based":[33],"sensors":[34],"offer":[35],"rapid":[36],"response":[37],"higher":[39],"selectivity,":[40],"fall":[42],"short":[43],"of":[44,131,133,141,153,162,181,203,209],"achieving":[45],"non-invasive":[46,149,178],"detection.":[47],"This":[48,125,144,170,187,223],"study":[49],"addresses":[50,216],"these":[51,106],"limitations":[52],"by":[53,85],"introducing":[54],"novel":[56,174],"approach":[57],"to":[58,69],"improve":[59],"performance.":[62],"We":[63],"employ":[64],"one-step":[66],"electrodeposition":[67],"method":[68],"synthesize":[70],"coat":[72],"structured":[73],"gold":[74],"nanoparticles":[75],"(Au":[76],"NPs)":[77],"onto":[78],"working":[80],"electrode,":[81],"optimizing":[82],"surface":[83],"morphology":[84],"manipulating":[86],"applied":[87],"voltage,":[88],"deposition":[89],"time,":[90],"reactant":[92],"concentrations.":[93],"The":[94,207],"resulting":[95],"nanostructured":[96],"Au":[97,115],"NPs":[98],"exhibit":[99],"diverse":[100],"previously":[102],"unreported":[103],"morphologies.":[104],"Leveraging":[105],"advancements,":[107],"we":[108],"design":[109],"wearable":[111,126,163,175,210],"device":[112],"integrating":[113],"the":[114,148,160,201,241],"NPs-based":[116],"sensor":[117,127,176],"with":[118],"structure-switch":[119],"aptamers":[120],"on":[121],"microfluidic":[123],"chip.":[124],"shows":[128],"limit":[130],"0.3":[134],"pg/mL":[135],"larger":[138],"linear":[139],"range":[140],"0.3-100":[142],"pg/mL.":[143],"innovation":[145,188],"allows":[146],"for":[147,166,177,231],"continuous":[151,179],"cytokines,":[154],"marking":[155,235],"significant":[157,237],"step":[158,238],"towards":[159],"development":[161,224],"electrochemical":[164,211],"biosensors":[165],"monitoring.Clinical":[168],"Relevance-":[169],"research":[171],"provides":[172],"monitoring":[180],"IFN-\u03b3":[183],"from":[184],"human":[185],"sweat.":[186],"holds":[189],"immense":[190],"clinical":[191,221],"relevance,":[192],"offering":[193],"real-time":[194],"insights":[195],"into":[196],"early":[197],"disease":[198],"responses":[199],"onset":[202],"non-communicable":[204],"conditions.":[206],"advancement":[208],"biosensors,":[212],"exhibiting":[213],"enhanced":[214],"performance,":[215],"crucial":[218],"need":[219],"practice.":[222],"offers":[225],"versatile":[227],"efficient":[229],"tool":[230],"patient-friendly":[232],"monitoring,":[234],"forward":[239],"field.":[242]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-08-29T07:29:34.045763","created_date":"2025-10-10T00:00:00"}