{"id":"https://openalex.org/W4405489683","doi":"https://doi.org/10.1109/embc53108.2024.10782737","title":"Counterfactual MRI Generation with Denoising Diffusion Models for Interpretable Alzheimer\u2019s Disease Effect Detection","display_name":"Counterfactual MRI Generation with Denoising Diffusion Models for Interpretable Alzheimer\u2019s Disease Effect Detection","publication_year":2024,"publication_date":"2024-07-15","ids":{"openalex":"https://openalex.org/W4405489683","doi":"https://doi.org/10.1109/embc53108.2024.10782737","pmid":"https://pubmed.ncbi.nlm.nih.gov/40039528"},"language":"en","primary_location":{"id":"doi:10.1109/embc53108.2024.10782737","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782737","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089189717","display_name":"Nikhil J. Dhinagar","orcid":"https://orcid.org/0000-0003-2424-4854"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nikhil J. Dhinagar","raw_affiliation_strings":["University of Southern California,Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine,Los Angeles,CA,USA"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine,Los Angeles,CA,USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017365268","display_name":"Sophia I. Thomopoulos","orcid":"https://orcid.org/0000-0002-0046-4070"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sophia I. Thomopoulos","raw_affiliation_strings":["University of Southern California,Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine,Los Angeles,CA,USA"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine,Los Angeles,CA,USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055654698","display_name":"Emily Laltoo","orcid":null},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily Laltoo","raw_affiliation_strings":["University of Southern California,Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine,Los Angeles,CA,USA"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine,Los Angeles,CA,USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100606557","display_name":"Paul M. Thompson","orcid":"https://orcid.org/0000-0002-4720-8867"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul M. Thompson","raw_affiliation_strings":["University of Southern California,Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine,Los Angeles,CA,USA"],"affiliations":[{"raw_affiliation_string":"University of Southern California,Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine,Los Angeles,CA,USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5089189717"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":null,"apc_paid":null,"fwci":1.6766,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.84715929,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9908000230789185,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9886999726295471,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/counterfactual-thinking","display_name":"Counterfactual thinking","score":0.7897263169288635},{"id":"https://openalex.org/keywords/noise-reduction","display_name":"Noise reduction","score":0.5363702774047852},{"id":"https://openalex.org/keywords/diffusion","display_name":"Diffusion","score":0.5298523902893066},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5286308526992798},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5244522094726562},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.5010809898376465},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.4601147770881653},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3943351209163666},{"id":"https://openalex.org/keywords/econometrics","display_name":"Econometrics","score":0.342589795589447},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.32697391510009766},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2571224570274353},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.24341759085655212},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.23535457253456116},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.21956881880760193},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.114865243434906},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.10281914472579956},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.10052824020385742}],"concepts":[{"id":"https://openalex.org/C108650721","wikidata":"https://www.wikidata.org/wiki/Q1783253","display_name":"Counterfactual thinking","level":2,"score":0.7897263169288635},{"id":"https://openalex.org/C163294075","wikidata":"https://www.wikidata.org/wiki/Q581861","display_name":"Noise reduction","level":2,"score":0.5363702774047852},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.5298523902893066},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5286308526992798},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5244522094726562},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.5010809898376465},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4601147770881653},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3943351209163666},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.342589795589447},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32697391510009766},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2571224570274353},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24341759085655212},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.23535457253456116},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.21956881880760193},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.114865243434906},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10281914472579956},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10052824020385742},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016477","descriptor_name":"Artifacts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016477","descriptor_name":"Artifacts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059629","descriptor_name":"Signal-To-Noise Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc53108.2024.10782737","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782737","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:40039528","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40039528","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.5,"id":"https://metadata.un.org/sdg/2"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320338440","display_name":"HORIZON EUROPE Health","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1980390607","https://openalex.org/W2117340355","https://openalex.org/W2522628945","https://openalex.org/W2786672974","https://openalex.org/W2963446712","https://openalex.org/W2979808915","https://openalex.org/W2995808388","https://openalex.org/W4288099666","https://openalex.org/W4297828509","https://openalex.org/W4312613321","https://openalex.org/W4312749295","https://openalex.org/W4312933868","https://openalex.org/W4323309573","https://openalex.org/W4379540358","https://openalex.org/W4386624665","https://openalex.org/W4387226001","https://openalex.org/W4392341509","https://openalex.org/W4394906559","https://openalex.org/W4401841076","https://openalex.org/W6688325169","https://openalex.org/W6748816842","https://openalex.org/W6783713337","https://openalex.org/W6840815571","https://openalex.org/W6853379143","https://openalex.org/W6857499674","https://openalex.org/W6861363789","https://openalex.org/W6864518445"],"related_works":["https://openalex.org/W3201448254","https://openalex.org/W4286970243","https://openalex.org/W2066431708","https://openalex.org/W4384133558","https://openalex.org/W3025615835","https://openalex.org/W173210993","https://openalex.org/W2390660599","https://openalex.org/W3028847759","https://openalex.org/W2393688264","https://openalex.org/W3170174360"],"abstract_inverted_index":{"Generative":[0],"AI":[1],"models":[2,54,60,82,162,183],"have":[3],"recently":[4],"achieved":[5],"mainstream":[6],"attention":[7],"with":[8],"the":[9,39,71,75,99,103,136,140,151,158,181,221,236,251,268],"advent":[10],"of":[11,26,42,130,139,150,160,223,235],"powerful":[12],"approaches":[13],"such":[14],"as":[15,106],"SORA,":[16],"DALL-E":[17],"and":[18,36,56,97,122,148,201,239,275,279,288],"stable":[19],"diffusion.":[20],"The":[21],"underlying":[22,40],"breakthrough":[23],"generative":[24,100],"mechanism":[25],"denoising":[27,57],"diffusion":[28,53,58,81,142,161,182],"modeling":[29],"can":[30,37],"generate":[31,85],"high":[32],"quality":[33,138],"synthetic":[34,86,153,185,277],"images":[35],"learn":[38],"distribution":[41],"complex,":[43],"high-dimensional":[44],"data.":[45],"In":[46,178],"our":[47,179],"paper,":[48],"we":[49,215],"train":[50,190],"conditional":[51],"latent":[52],"(LDM)":[55],"probabilistic":[59],"(DDPM)":[61],"to":[62,113,145,163,175,189,219,228,262],"provide":[63],"insight":[64],"into":[65],"Alzheimer's":[66],"disease":[67,172,258,265],"(AD)":[68],"effects":[69,129,266],"on":[70,91,102,210,267],"brain's":[72],"anatomy":[73],"at":[74],"individual":[76,226],"level.":[77],"We":[78,110,134,155],"first":[79],"created":[80],"that":[83,187],"could":[84],"MRIs,":[87],"by":[88,125,205],"training":[89,117,132],"them":[90],"real":[92,176,197,211],"3D":[93,170],"T1-weighted":[94],"MRI":[95,166,198,212],"scans,":[96],"conditioning":[98,222],"process":[101],"clinical":[104,289],"diagnosis":[105],"a":[107,169,232,256],"context":[108],"variable.":[109],"conducted":[111],"experiments":[112],"overcome":[114],"limitations":[115],"in":[116],"dataset":[118],"size,":[119],"compute":[120],"time":[121],"memory":[123],"resources":[124],"testing":[126],"different":[127],"models,":[128],"pretraining,":[131],"duration.":[133],"tested":[135,209],"sampling":[137],"disease-conditioned":[141],"using":[143,168],"metrics":[144],"assess":[146],"realism":[147],"diversity":[149],"generated":[152,184,261],"MRIs.":[154,177],"also":[156],"evaluated":[157],"ability":[159],"conditionally":[164],"sample":[165],"brains":[167],"CNN-based":[171],"classifier":[173,193],"relative":[174],"experiments,":[180],"data":[186],"helped":[188],"an":[191,224],"AD":[192],"(using":[194],"only":[195],"500":[196],"scans)":[199],"-":[200],"boosted":[202],"its":[203,229],"performance":[204],"over":[206],"3%":[207],"when":[208],"scans.":[213],"Further,":[214],"used":[216],"classifier-free":[217],"guidance":[218],"alter":[220],"encoded":[225],"scan":[227],"counterfactual":[230,248],"(representing":[231],"healthy":[233],"subject":[234],"same":[237,252],"age":[238],"sex)":[240],"while":[241],"preserving":[242],"subject-specific":[243],"image":[244,249],"details.":[245],"From":[246],"this":[247],"(where":[250],"person":[253],"appears":[254],"healthy),":[255],"personalized":[257],"map":[259],"was":[260],"identify":[263],"possible":[264],"brain.":[269],"Our":[270],"approach":[271],"efficiently":[272],"generates":[273],"realistic":[274],"diverse":[276],"data,":[278],"may":[280],"create":[281],"interpretable":[282],"AI-based":[283],"maps":[284],"for":[285],"neuroscience":[286],"research":[287],"diagnostic":[290],"applications.":[291]},"counts_by_year":[{"year":2025,"cited_by_count":7}],"updated_date":"2026-04-15T08:11:43.952461","created_date":"2025-10-10T00:00:00"}