{"id":"https://openalex.org/W4405489360","doi":"https://doi.org/10.1109/embc53108.2024.10782615","title":"The longitudinal study of morphometric measurement changes in progressive supranuclear palsy","display_name":"The longitudinal study of morphometric measurement changes in progressive supranuclear palsy","publication_year":2024,"publication_date":"2024-07-15","ids":{"openalex":"https://openalex.org/W4405489360","doi":"https://doi.org/10.1109/embc53108.2024.10782615","pmid":"https://pubmed.ncbi.nlm.nih.gov/40039207"},"language":"en","primary_location":{"id":"doi:10.1109/embc53108.2024.10782615","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782615","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070796737","display_name":"Ronghua Ling","orcid":"https://orcid.org/0009-0006-6768-5691"},"institutions":[{"id":"https://openalex.org/I4210135985","display_name":"Shanghai University of Medicine and Health Sciences","ror":"https://ror.org/03ns6aq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210135985"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ronghua Ling","raw_affiliation_strings":["Shanghai University of Medicine &#x0026; Health Science,School of Medical Imaging,Shanghai,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai University of Medicine &#x0026; Health Science,School of Medical Imaging,Shanghai,China","institution_ids":["https://openalex.org/I4210135985"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yinghui Yang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210154361","display_name":"Shanghai Jian Qiao University","ror":"https://ror.org/04xdqtw10","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210154361"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yinghui Yang","raw_affiliation_strings":["Shanghai Jian Qiao University,College of Health Management,Shanghai,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Jian Qiao University,College of Health Management,Shanghai,China","institution_ids":["https://openalex.org/I4210154361"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061511786","display_name":"Juanjuan Jiang","orcid":"https://orcid.org/0000-0003-1875-4807"},"institutions":[{"id":"https://openalex.org/I70908550","display_name":"Anhui Polytechnic University","ror":"https://ror.org/041sj0284","country_code":"CN","type":"education","lineage":["https://openalex.org/I70908550"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juanjuan Jiang","raw_affiliation_strings":["Anhui Polytechnic University,School of Electrical Engineering,Wuhu,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Polytechnic University,School of Electrical Engineering,Wuhu,China","institution_ids":["https://openalex.org/I70908550"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100340951","display_name":"Min Wang","orcid":"https://orcid.org/0000-0002-9233-7844"},"institutions":[{"id":"https://openalex.org/I113940042","display_name":"Shanghai University","ror":"https://ror.org/006teas31","country_code":"CN","type":"education","lineage":["https://openalex.org/I113940042"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Wang","raw_affiliation_strings":["Shanghai University,School of Life Sciences,Shanghai,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai University,School of Life Sciences,Shanghai,China","institution_ids":["https://openalex.org/I113940042"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5070796737"],"corresponding_institution_ids":["https://openalex.org/I4210135985"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35543552,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/progressive-supranuclear-palsy","display_name":"Progressive supranuclear palsy","score":0.9666754007339478},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2682619094848633},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.15978354215621948},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.06705522537231445}],"concepts":[{"id":"https://openalex.org/C2776477761","wikidata":"https://www.wikidata.org/wiki/Q945930","display_name":"Progressive supranuclear palsy","level":3,"score":0.9666754007339478},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2682619094848633},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.15978354215621948},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.06705522537231445}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008636","descriptor_name":"Mesencephalon","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc53108.2024.10782615","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782615","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:40039207","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40039207","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320325553","display_name":"Shanghai University","ror":"https://ror.org/006teas31"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W2093848908","https://openalex.org/W2096937017","https://openalex.org/W2142406431","https://openalex.org/W2513116854","https://openalex.org/W2608077212","https://openalex.org/W2623663856","https://openalex.org/W2893604114","https://openalex.org/W2973597369","https://openalex.org/W2998942804","https://openalex.org/W3004383120","https://openalex.org/W3007744961","https://openalex.org/W3096824524","https://openalex.org/W3164978586","https://openalex.org/W3193873334","https://openalex.org/W4223424674","https://openalex.org/W4280580630","https://openalex.org/W4286111153","https://openalex.org/W4292686852","https://openalex.org/W4319460770"],"related_works":["https://openalex.org/W2610345351","https://openalex.org/W3005390831","https://openalex.org/W3086086536","https://openalex.org/W4323045437","https://openalex.org/W4319151857","https://openalex.org/W2771646997","https://openalex.org/W4401406859","https://openalex.org/W2346986130","https://openalex.org/W2953052250","https://openalex.org/W4244035777"],"abstract_inverted_index":{"Midbrain":[0],"atrophy":[1],"is":[2],"strongly":[3],"associated":[4,90],"with":[5,62,66,74,91],"progressive":[6],"supranuclear":[7],"palsy":[8],"(PSP)":[9],"disease":[10,63,112],"severity.":[11],"Preclinical":[12],"evidence":[13],"suggests":[14],"that":[15,103],"midbrain-based":[16,104],"Magnetic":[17],"Resonance":[18],"Parkinsonism":[19],"Index":[20],"(MRPI)":[21],"measurements":[22,40,46,82,87,106],"are":[23],"reliable":[24],"and":[25,47,55],"sensitive":[26],"morphometric":[27,45,81],"biomarkers":[28],"for":[29,109],"PSP":[30,42,75,93,111],"diagnosis.":[31],"The":[32],"study":[33,101],"explored":[34],"the":[35,48,60],"longitudinal":[36],"changes":[37,52],"of":[38],"MRPI":[39,105],"in":[41,72,79],"patients.":[43],"Midbrain-based":[44],"corresponding":[49],"annual":[50],"percentage":[51],"were":[53,88],"measured":[54],"further":[56],"used":[57],"to":[58],"evaluate":[59],"associations":[61],"progression.":[64,113],"Compared":[65],"healthy":[67],"controls,":[68],"baseline":[69,92],"quantitative":[70],"analyses":[71],"patients":[73],"revealed":[76],"significant":[77],"differences":[78],"all":[80],"expect":[83],"pons.":[84],"Baseline":[85],"comprehensive":[86],"significantly":[89],"rating":[94],"scale":[95],"score":[96],"(P":[97],"<":[98],"0.05).":[99],"Our":[100],"demonstrates":[102],"holds":[107],"promise":[108],"monitoring":[110]},"counts_by_year":[],"updated_date":"2026-05-08T15:41:06.802602","created_date":"2025-10-10T00:00:00"}