{"id":"https://openalex.org/W4405490363","doi":"https://doi.org/10.1109/embc53108.2024.10782443","title":"Towards the development of a FAIR-compliant biomedical ontology for colorectal cancer","display_name":"Towards the development of a FAIR-compliant biomedical ontology for colorectal cancer","publication_year":2024,"publication_date":"2024-07-15","ids":{"openalex":"https://openalex.org/W4405490363","doi":"https://doi.org/10.1109/embc53108.2024.10782443","pmid":"https://pubmed.ncbi.nlm.nih.gov/40039630"},"language":"en","primary_location":{"id":"doi:10.1109/embc53108.2024.10782443","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782443","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.1109/EMBC53108.2024.10782443","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074234790","display_name":"Vasileios C. Pezoulas","orcid":"https://orcid.org/0000-0002-1872-693X"},"institutions":[{"id":"https://openalex.org/I4210105723","display_name":"FORTH Institute of Molecular Biology and Biotechnology","ror":"https://ror.org/01gzszr18","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Vasileios Pezoulas","raw_affiliation_strings":["Unit of Medical Technology and Intelligent Information Systems,FORTH-IMBB, GR,Dept. of Materials Science and Engineering, and Biomedical Resarch Institute (BRI),Ioannina,Greece,45110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Medical Technology and Intelligent Information Systems,FORTH-IMBB, GR,Dept. of Materials Science and Engineering, and Biomedical Resarch Institute (BRI),Ioannina,Greece,45110","institution_ids":["https://openalex.org/I4210105723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007799423","display_name":"Christos Androutsos","orcid":null},"institutions":[{"id":"https://openalex.org/I4210105723","display_name":"FORTH Institute of Molecular Biology and Biotechnology","ror":"https://ror.org/01gzszr18","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Christos Androutsos","raw_affiliation_strings":["Unit of Medical Technology and Intelligent Information Systems,FORTH-IMBB, GR,Dept. of Materials Science and Engineering, and Biomedical Resarch Institute,Ioannina,Greece,45110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Medical Technology and Intelligent Information Systems,FORTH-IMBB, GR,Dept. of Materials Science and Engineering, and Biomedical Resarch Institute,Ioannina,Greece,45110","institution_ids":["https://openalex.org/I4210105723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057894101","display_name":"Dimitrios I. Fotiadis","orcid":"https://orcid.org/0000-0002-5987-9350"},"institutions":[{"id":"https://openalex.org/I4210105723","display_name":"FORTH Institute of Molecular Biology and Biotechnology","ror":"https://ror.org/01gzszr18","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Dimitrios I. Fotiadis","raw_affiliation_strings":["Unit of Medical Technology and Intelligent Information Systems,FORTH-IMBB, GR,Dept. of Materials Science and Engineering, and Biomedical Resarch Institute (BRI),Ioannina,Greece,45110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Medical Technology and Intelligent Information Systems,FORTH-IMBB, GR,Dept. of Materials Science and Engineering, and Biomedical Resarch Institute (BRI),Ioannina,Greece,45110","institution_ids":["https://openalex.org/I4210105723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210105723"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11937","display_name":"Research Data Management Practices","score":0.9866999983787537,"subfield":{"id":"https://openalex.org/subfields/1710","display_name":"Information Systems"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10215","display_name":"Semantic Web and Ontologies","score":0.9728000164031982,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"Colorectal cancer","score":0.6663252711296082},{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.6495779752731323},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5624513626098633},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.45387402176856995},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.28006649017333984},{"id":"https://openalex.org/keywords/philosophy","display_name":"Philosophy","score":0.1282104253768921},{"id":"https://openalex.org/keywords/epistemology","display_name":"Epistemology","score":0.10240712761878967},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.10055804252624512}],"concepts":[{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6663252711296082},{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.6495779752731323},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5624513626098633},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.45387402176856995},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28006649017333984},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.1282104253768921},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.10240712761878967},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10055804252624512}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc53108.2024.10782443","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10782443","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:40039630","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40039630","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:zenodo.org:18324830","is_oa":true,"landing_page_url":"https://doi.org/10.1109/EMBC53108.2024.10782443","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferencePaper"}],"best_oa_location":{"id":"pmh:oai:zenodo.org:18324830","is_oa":true,"landing_page_url":"https://doi.org/10.1109/EMBC53108.2024.10782443","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferencePaper"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6100000143051147}],"awards":[],"funders":[{"id":"https://openalex.org/F4320314731","display_name":"UK Research and Innovation","ror":"https://ror.org/001aqnf71"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W2579357550","https://openalex.org/W2766726453","https://openalex.org/W2988998130","https://openalex.org/W2996304603","https://openalex.org/W3110795479","https://openalex.org/W4205824053","https://openalex.org/W4210681325","https://openalex.org/W4244876068","https://openalex.org/W4285021577","https://openalex.org/W4323858836","https://openalex.org/W4377096495","https://openalex.org/W4387341807","https://openalex.org/W4390578581"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Despite":[0],"the":[1,11,22,30,84,146,161,171,188],"widespread":[2],"development":[3],"of":[4,9,13,24,86,150],"ontologies":[5],"in":[6,145,187],"many":[7],"domains":[8],"healthcare,":[10],"field":[12],"colorectal":[14],"cancer":[15],"(CRC)":[16],"presents":[17,114],"a":[18,39,115,181],"notable":[19],"gap":[20],"considering":[21],"lack":[23],"standardized":[25],"data":[26,49,122,158],"models":[27],"tailored":[28],"to":[29,43,59,93,163],"CRC":[31,119,166],"domain.":[32],"To":[33],"address":[34],"this":[35],"gap,":[36],"we":[37],"developed":[38],"structured,":[40],"systematic":[41],"approach":[42],"model":[44,50,159],"CRC-related":[45],"data.":[46],"A":[47],"reference":[48],"(RDM)":[51],"was":[52,69,103],"first":[53],"defined,":[54],"including":[55,76],"250":[56],"terminologies":[57],"related":[58],"sociodemographics,":[60],"clinical":[61],"biology,":[62],"lifestyle,":[63],"symptoms,":[64],"among":[65,81],"others.":[66],"Each":[67],"terminology":[68],"linked":[70],"with":[71],"globally":[72],"recognized":[73],"HL7":[74],"standards,":[75],"SNOMED-CT,":[77],"LOINC,":[78],"and":[79,90,128,143,156,168,179],"ICD-10/11,":[80],"others,":[82],"fulfilling":[83],"principles":[85],"findability,":[87],"accessibility,":[88],"interoperability,":[89],"reusability":[91],"(FAIR)":[92],"facilitate":[94],"its":[95,140],"integration":[96],"into":[97,106],"global":[98,137],"healthcare":[99,126],"systems.":[100],"The":[101,111,131,152],"RDM":[102],"then":[104],"transformed":[105],"an":[107],"ontology":[108,113],"using":[109],"Prot\u00e9g\u00e9.":[110],"resulting":[112],"unified":[116],"framework":[117],"for":[118,173,184],"data,":[120],"enhancing":[121],"consistency":[123],"across":[124],"various":[125],"platforms":[127],"research":[129,167],"studies.":[130],"ontology's":[132],"availability":[133],"on":[134],"GitHub":[135],"invites":[136],"collaboration,":[138],"ensuring":[139],"continual":[141],"evolution":[142],"relevance":[144],"rapidly":[147],"advancing":[148],"landscape":[149],"healthcare.":[151],"proposed":[153],"standardized,":[154],"accessible,":[155],"comprehensive":[157],"has":[160],"potential":[162],"significantly":[164],"impact":[165],"treatment,":[169],"paving":[170],"way":[172],"more":[174],"effective,":[175],"personalized":[176],"patient":[177],"care":[178],"fostering":[180],"collaborative":[182],"environment":[183],"ongoing":[185],"advancements":[186],"field.":[189]},"counts_by_year":[],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}